Early developability screen of therapeutic antibody candidates using Taylor dispersion analysis and UV area imaging detection

High-throughput viscosity measurement using capillary electrophoresis instrumentation and its application to protein formulation

(2014) Andrea Allmendinger et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Conformational Change of Bovine Serum Albumin Molecules at Neutral pH in Ultra-Diluted Aqueous Solutions

(2014) Shulian He et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Dipole-Dipole Interaction in Antibody Solutions: Correlation with Viscosity Behavior at High Concentration

(2014) Shubhadra N. Singh et al.   PHARMACEUTICAL RESEARCH

Concentration Dependent Viscosity of Monoclonal Antibody Solutions: Explaining Experimental Behavior in Terms of Molecular Properties

(2014) Li Li et al.   PHARMACEUTICAL RESEARCH

Evaluating the inter and intra batch variability of protein aggregation behaviour using Taylor dispersion analysis and dynamic light scattering

(2013) Wendy L. Hulse et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Antibodies to watch in 2014

(2013) Janice M Reichert   mAbs

Developability studies before initiation of process development

(2013) Xiaoyu Yang et al.   mAbs

High-throughput screening for developability during early-stage antibody discovery using self-interaction nanoparticle spectroscopy

(2013) Yuqi Liu et al.   mAbs

High throughput detection of antibody self-interaction by bio-layer interferometry

(2013) Tingwan Sun et al.   mAbs

Rapid Analysis of Antibody Self-Association in Complex Mixtures Using Immunogold Conjugates

(2013) Shantanu V. Sule et al.   MOLECULAR PHARMACEUTICS

Weak Interactions Govern the Viscosity of Concentrated Antibody Solutions: High-Throughput Analysis Using the Diffusion Interaction Parameter

(2012) Brian D. Connolly et al.   BIOPHYSICAL JOURNAL

Quality attributes of recombinant therapeutic proteins: An assessment of impact on safety and efficacy as part of a quality by design development approach

(2012) Alex Eon-Duval et al.   BIOTECHNOLOGY PROGRESS

The impact of glycosylation on monoclonal antibody conformation and stability

(2012) Kai Zheng et al.   mAbs

The Influence of Charge Distribution on Self-Association and Viscosity Behavior of Monoclonal Antibody Solutions

(2012) Sandeep Yadav et al.   MOLECULAR PHARMACEUTICS

High-Throughput Analysis of Concentration-Dependent Antibody Self-Association

(2011) Shantanu V. Sule et al.   BIOPHYSICAL JOURNAL

A nanolitre method to determine the hydrodynamic radius of proteins and small molecules by Taylor dispersion analysis

(2011) Wendy L. Hulse et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A Taylor dispersion analysis method for the sizing of therapeutic proteins and their aggregates using nanolitre sample quantities

(2011) Wendy Hulse et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

High‐Throughput Assessment of Thermal and Colloidal Stability Parameters for Monoclonal Antibody Formulations

(2011) Feng He et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

High Affinity, Developability and Functional Size: The Holy Grail of Combinatorial Antibody Library Generation

(2011) Dirk Ponsel et al.   MOLECULES

Taylor Dispersion Analysis Compared to Dynamic Light Scattering for the Size Analysis of Therapeutic Peptides and Proteins and Their Aggregates

(2011) Andrea Hawe et al.   PHARMACEUTICAL RESEARCH

Hydrophobic salts markedly diminish viscosity of concentrated protein solutions

(2010) Wei Du et al.   BIOTECHNOLOGY AND BIOENGINEERING

Rheological and syringeability properties of highly concentrated human polyclonal immunoglobulin solutions

(2010) V. Burckbuchler et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

High-throughput dynamic light scattering method for measuring viscosity of concentrated protein solutions

(2009) Feng He et al.   ANALYTICAL BIOCHEMISTRY

Nature and consequences of protein–protein interactions in high protein concentration solutions

(2008) Atul Saluja et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Reversible Self-Association of a Concentrated Monoclonal Antibody Solution Mediated by Fab–Fab Interaction That Impacts Solution Viscosity

(2008) Sonoko Kanai et al.   JOURNAL OF PHARMACEUTICAL SCIENCES