标题
Role of spleen tyrosine kinase in the pathogenesis of chronic lymphocytic leukemia
作者
关键词
-
出版物
LEUKEMIA & LYMPHOMA
Volume 55, Issue 12, Pages 2699-2705
出版商
Informa UK Limited
发表日期
2014-02-19
DOI
10.3109/10428194.2014.891026
参考文献
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- (2013) M. Binder et al. BLOOD
- A mutated B cell chronic lymphocytic leukemia subset that recognizes and responds to fungi
- (2013) Robbert Hoogeboom et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies
- (2012) A. Agathangelidis et al. BLOOD
- Chronic lymphocytic leukemia: A tale of one or two signals?
- (2012) Nicholas Chiorazzi et al. CELL RESEARCH
- Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration
- (2012) J Hoellenriegel et al. LEUKEMIA
- Expression levels of Lyn, Syk, PLCγ2 and ERK in patients with chronic lymphocytic leukemia, and higher levels of Lyn are associated with a shorter treatment-free survival
- (2012) Yin-Hua Wang et al. LEUKEMIA & LYMPHOMA
- Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling
- (2012) Marcus Dühren-von Minden et al. NATURE
- B-cell receptor signaling in chronic lymphocytic leukemia
- (2011) F. K. Stevenson et al. BLOOD
- Phase II Study of Dasatinib in Relapsed or Refractory Chronic Lymphocytic Leukemia
- (2011) P. C. Amrein et al. CLINICAL CANCER RESEARCH
- The lymph node microenvironment promotes B-cell receptor signaling, NF- B activation, and tumor proliferation in chronic lymphocytic leukemia
- (2010) Y. Herishanu et al. BLOOD
- The Syk inhibitor fostamatinib disodium (R788) inhibits tumor growth in the E - TCL1 transgenic mouse model of CLL by blocking antigen-dependent B-cell receptor signaling
- (2010) M. Suljagic et al. BLOOD
- MALT lymphoma-derived rheumatoid factors are nonpolyreactive high-affinity antibodies
- (2010) R. Hoogeboom et al. BLOOD
- PRT-060318, a novel Syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model
- (2010) M. P. Reilly et al. BLOOD
- Spleen tyrosine kinase inhibition prevents chemokine- and integrin-mediated stromal protective effects in chronic lymphocytic leukemia
- (2010) M. Buchner et al. BLOOD
- SYK carries no activating point mutations in patients with chronic lymphocytic leukaemia (CLL)
- (2010) Angela Philippen et al. BRITISH JOURNAL OF HAEMATOLOGY
- Current and Emerging Treatments for Chronic Lymphocytic Leukaemia
- (2010) Tadeusz Robak et al. DRUGS
- B-cell receptor signaling and CD40 ligand-independent T cell help cooperate in Helicobacter-induced MALT lymphomagenesis
- (2010) V J Craig et al. LEUKEMIA
- An Oral Spleen Tyrosine Kinase (Syk) Inhibitor for Rheumatoid Arthritis
- (2010) Michael E. Weinblatt et al. NEW ENGLAND JOURNAL OF MEDICINE
- ZAP-70: An Essential Kinase in T-cell Signaling
- (2010) H. Wang et al. Cold Spring Harbor Perspectives in Biology
- Syk and pTyr'd: Signaling through the B cell antigen receptor
- (2009) Robert L. Geahlen BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406
- (2009) M. P. Quiroga et al. BLOOD
- Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia
- (2009) J. W. Friedberg et al. BLOOD
- Spleen Tyrosine Kinase Is Overexpressed and Represents a Potential Therapeutic Target in Chronic Lymphocytic Leukemia
- (2009) Maike Buchner et al. CANCER RESEARCH
- PI3 Kinase Signals BCR-Dependent Mature B Cell Survival
- (2009) Lakshmi Srinivasan et al. CELL
- Phosphorylation of the activation loop tyrosines is required for sustained Syk signaling and growth factor-independent B-cell proliferation
- (2009) Laura Carsetti et al. CELLULAR SIGNALLING
- Correlation of flow cytometrically determined expression of ZAP-70 using the SBZAP antibody with IgVH mutation status and cytogenetics in 1,229 patients with chronic lymphocytic leukemia
- (2009) Wolfgang Kern et al. CYTOMETRY PART B-CLINICAL CYTOMETRY
- Protein Tyrosine Kinase, Syk: A Key Player in Phagocytic Cells
- (2009) Y. Tohyama et al. JOURNAL OF BIOCHEMISTRY
- Essential function for the GTPase TC21 in homeostatic antigen receptor signaling
- (2009) Pilar Delgado et al. NATURE IMMUNOLOGY
- The tyrosine kinase Syk regulates the survival of chronic lymphocytic leukemia B cells through PKCδ and proteasome-dependent regulation of Mcl-1 expression
- (2009) A D Baudot et al. ONCOGENE
- Treatment of rheumatoid arthritis with a syk kinase inhibitor: A twelve-week, randomized, placebo-controlled trial
- (2008) Michael E. Weinblatt et al. ARTHRITIS AND RHEUMATISM
- High-level expression of the T-cell chemokines CCL3 and CCL4 by chronic lymphocytic leukemia B cells in nurselike cell cocultures and after BCR stimulation
- (2008) J. A. Burger et al. BLOOD
- Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia
- (2008) L. Z. Rassenti et al. BLOOD
- Mouse models of non-Hodgkin lymphoma reveal Syk as an important therapeutic target
- (2008) R. M. Young et al. BLOOD
- Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
- (2008) M. Hallek et al. BLOOD
- ZAP-70 and CD38 expression are independent prognostic factors in patients with B-cell chronic lymphocytic leukaemia and combined analysis improves their predictive value.
- (2008) Iwona Hus et al. FOLIA HISTOCHEMICA ET CYTOBIOLOGICA
- Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells
- (2008) S Gobessi et al. LEUKEMIA
- Combinations of ZAP-70, CD38 and IGHV mutational status as predictors of time to first treatment in CLL
- (2008) Alison Morilla et al. LEUKEMIA & LYMPHOMA
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