The Syk inhibitor fostamatinib disodium (R788) inhibits tumor growth in the E - TCL1 transgenic mouse model of CLL by blocking antigen-dependent B-cell receptor signaling
出版年份 2010 全文链接
标题
The Syk inhibitor fostamatinib disodium (R788) inhibits tumor growth in the E - TCL1 transgenic mouse model of CLL by blocking antigen-dependent B-cell receptor signaling
作者
关键词
-
出版物
BLOOD
Volume 116, Issue 23, Pages 4894-4905
出版商
American Society of Hematology
发表日期
2010-08-18
DOI
10.1182/blood-2010-03-275180
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Many chronic lymphocytic leukemia antibodies recognize apoptotic cells with exposed nonmuscle myosin heavy chain IIA: implications for patient outcome and cell of origin
- (2010) C. C. Chu et al. BLOOD
- Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma
- (2010) R. Eric Davis et al. NATURE
- PKC is essential for the development of chronic lymphocytic leukemia in the TCL1 transgenic mouse model: validation of PKC as a therapeutic target in chronic lymphocytic leukemia
- (2009) C. Holler et al. BLOOD
- B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406
- (2009) M. P. Quiroga et al. BLOOD
- The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo
- (2009) David M. Lucas et al. BLOOD
- Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia
- (2009) J. W. Friedberg et al. BLOOD
- Spleen Tyrosine Kinase Is Overexpressed and Represents a Potential Therapeutic Target in Chronic Lymphocytic Leukemia
- (2009) Maike Buchner et al. CANCER RESEARCH
- Chronic inflammatory disease, lymphoid tissue neogenesis and extranodal marginal zone B-cell lymphomas
- (2009) R. J. Bende et al. HAEMATOLOGICA
- Involvement of RhoH GTPase in the development of B-cell chronic lymphocytic leukemia
- (2009) A Sanchez-Aguilera et al. LEUKEMIA
- The tyrosine kinase Syk regulates the survival of chronic lymphocytic leukemia B cells through PKCδ and proteasome-dependent regulation of Mcl-1 expression
- (2009) A D Baudot et al. ONCOGENE
- E -TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction
- (2009) G. Gorgun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Treatment of rheumatoid arthritis with a syk kinase inhibitor: A twelve-week, randomized, placebo-controlled trial
- (2008) Michael E. Weinblatt et al. ARTHRITIS AND RHEUMATISM
- Of mice and men: an open-label pilot study for treatment of immune thrombocytopenic purpura by an inhibitor of Syk
- (2008) A. Podolanczuk et al. BLOOD
- A new perspective: molecular motifs on oxidized LDL, apoptotic cells, and bacteria are targets for chronic lymphocytic leukemia antibodies
- (2008) A. Lanemo Myhrinder et al. BLOOD
- Chronic lymphocytic leukemia antibodies with a common stereotypic rearrangement recognize nonmuscle myosin heavy chain IIA
- (2008) C. C. Chu et al. BLOOD
- Mouse models of non-Hodgkin lymphoma reveal Syk as an important therapeutic target
- (2008) R. M. Young et al. BLOOD
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