Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse

Postrelapse survival in childhood acute lymphoblastic leukemia is independent of initial treatment intensity: a report from the Children's Oncology Group

(2010) D. R. Freyer et al.   BLOOD

Genome-wide expression analysis of paired diagnosis–relapse samples in ALL indicates involvement of pathways related to DNA replication, cell cycle and DNA repair, independent of immune phenotype

(2010) F J T Staal et al.   LEUKEMIA

Genetic variegation of clonal architecture and propagating cells in leukaemia

(2010) Kristina Anderson et al.   NATURE

Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271

(2010) Alexander D. Boiko et al.   NATURE

Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia

(2010) Maria Kleppe et al.   NATURE GENETICS

WT1 mutations in T-ALL

(2009) V. Tosello et al.   BLOOD

High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia

(2009) A. Gutierrez et al.   BLOOD

Heterogeneity in Cancer: Cancer Stem Cells versus Clonal Evolution

(2009) Mark Shackleton et al.   CELL

Optimized gene transfer into human primary leukemic T cell with NOD-SCID/leukemia-initiating cell activity

(2009) B Gerby et al.   LEUKEMIA

Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia

(2008) J. J. Yang et al.   BLOOD

Stem cell concepts renew cancer research

(2008) J. E. Dick   BLOOD

NOTCH is a key regulator of human T-cell acute leukemia initiating cell activity

(2008) F. Armstrong et al.   BLOOD

Molecular-genetic insights in paediatric T-cell acute lymphoblastic leukaemia

(2008) Pieter Van Vlierberghe et al.   BRITISH JOURNAL OF HAEMATOLOGY

Acute lymphoblastic leukaemia

(2008) Ching-Hon Pui et al.   LANCET

Bone-marrow relapse in paediatric acute lymphoblastic leukaemia

(2008) L Charles Bailey et al.   LANCET ONCOLOGY

γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

(2008) Pedro J Real et al.   NATURE MEDICINE

Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic Leukemia

(2008) C. G. Mullighan et al.   SCIENCE