The role of TLR8 signaling in acute myeloid leukemia differentiation

Identification of RNA Sequence Motifs Stimulating Sequence-Specific TLR8-Dependent Immune Responses

(2014) A. Forsbach et al.   JOURNAL OF IMMUNOLOGY

p70S6 kinase is a target of the novel proteasome inhibitor 3,3′-diamino-4′-methoxyflavone during apoptosis in human myeloid tumor cells

(2013) Marion Piedfer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Pivotal role for ROS activation of p38 MAPK in the control of differentiation and tumor-initiating capacity of glioma-initiating cells

(2013) Atsushi Sato et al.   Stem Cell Research

GSK3 is a regulator of RAR-mediated differentiation

(2012) K Gupta et al.   LEUKEMIA

VTX-2337 Is a Novel TLR8 Agonist That Activates NK Cells and Augments ADCC

(2011) H. Lu et al.   CLINICAL CANCER RESEARCH

Regulation of T cell activation by TLR ligands

(2011) Hans-Heinrich Oberg et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Targeting Toll-like receptors: emerging therapeutics?

(2010) Elizabeth J. Hennessy et al.   NATURE REVIEWS DRUG DISCOVERY

Toll-like Receptors (TLRs) are expressed by myeloid leukaemia cell lines, but fail to trigger differentiation in response to the respective TLR ligands

(2009) Masashi Okamoto et al.   BRITISH JOURNAL OF HAEMATOLOGY

p38α blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1α- to FoxO-dependent transcription

(2009) F Chiacchiera et al.   CELL DEATH AND DIFFERENTIATION

TLR7 and TLR8 agonists trigger different signaling pathways for human dendritic cell maturation

(2009) A. Larange et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology

(2008) S. Baenziger et al.   BLOOD

Identification of 6-Benzylthioinosine as a Myeloid Leukemia Differentiation-Inducing Compound

(2008) D. N. Wald et al.   CANCER RESEARCH

Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy

(2008) Zhong Wang et al.   NATURE

Bacterial targeted tumour therapy-dawn of a new era

(2007) Ming Q Wei et al.   CANCER LETTERS