Review
Chemistry, Multidisciplinary
Alemayehu Nana Koya, Xiangchao Zhu, Nareg Ohannesian, A. Ali Yanik, Alessandro Alabastri, Remo Proietti Zaccaria, Roman Krahne, Wei-Chuan Shih, Denis Garoli
Summary: This paper reviews the properties and potential applications of nanoporous metals as plasmonic materials, but lacks a detailed discussion on their connection with surface plasmons, enhanced spectroscopies, and photocatalysis.
Review
Biotechnology & Applied Microbiology
Jialin Wu, Hui Fang, Jun Zhang, Sheng Yan
Summary: The advancement of microfluidics has led to significant discoveries and technologies in life sciences. However, the lack of industry standards and configurability has made the design and fabrication of microfluidic devices challenging. Modular microfluidics, which integrates standardized microfluidic modules into a complex platform, offers portability, on-site deployability, and high customization. In this review, we discuss the working mechanisms of basic microfluidic modules, their feasibility as modular components, connection approaches, advantages over integrated microfluidics, and future perspectives.
JOURNAL OF NANOBIOTECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Wen-Jeng Ho, Jheng-Jie Liu, Jhih-Ciang Chen
Summary: This study investigated the plasmonic effects of silver nanoparticles, the luminescent down-shifting of Eu-doped phosphor particles, and metal-enhanced fluorescence. By combining these processes, the conversion efficiency of silicon solar cells was significantly enhanced.
Article
Chemistry, Analytical
Jia-Sheng Lin, Petar M. Radjenovic, Huaizhou Jin, Jian-Feng Li
Summary: Plasmonic core-shell nanoparticle enhanced spectroscopies are promising tools for qualitatively and quantitatively analyzing surface trace species. Four different working modalities are designed to meet various needs, including in situ surface species detection, catalytic process monitoring, labeled sensing, and dual mode analysis. These newly developed plasmonic spectroscopies show great potential in both fundamental research and practical applications.
ANALYTICAL CHEMISTRY
(2021)
Review
Biology
Abhaya Bhardwaj, Shristi Kishore, Dhananjay K. Pandey
Summary: Artificial intelligence has the potential to improve various fields of biology, such as medicine, agriculture, and bio-based industry, by providing more precise diagnosis, cost-effective treatment, increased output, and decreased waste.
Review
Plant Sciences
Shakeel Ahmed, Jiandong Hu, Syed M. Z. A. Naqvi, Yanyan Zhang, Li Linze, Abdulraheem M. Iderawumi
Summary: In the future, plant molecular biology and bacterial behavior research could utilize genetically engineered bacteria as sensors, hormonal/disease detectors, and target gene expressors, and establish a bioluminescence feedback communication system. Understanding plant signal transduction pathways and using molecular communication can provide valuable insights into plant behavior and have important applications in various fields.
Review
Chemistry, Physical
Jinghua Li, Yiming Zhang, Yalong Huang, Bing Luo, Li Jing, Dengwei Jing
Summary: Plasmonic nanomaterial catalysis is a frontier research area in photocatalysis, offering a solution to the limitations of wide bandgap semiconductors. This paper reviews the principles, classification, and recent applications of noble-metal free plasmonic nanomaterials in photocatalytic reactions, including hydrogen generation, carbon dioxide reduction, and pollutant degradation. It also discusses the challenges and future opportunities for the development of noble-metal free plasmonic nanomaterials in energy conversion and storage.
Article
Chemistry, Multidisciplinary
Priyash Barya, Yanyu Xiong, Skye Shepherd, Rohit Gupta, Lucas D. Akin, Joseph Tibbs, Hankeun Lee, Srikanth Singamaneni, Brian T. Cunningham
Summary: Assays using fluorophores are common in life science research and diagnostics. However, weak emission intensity limits the detection limits, requiring a large number of labeled target molecules to improve signal-to-noise ratio. This study demonstrates that the synergistic coupling of plasmonic and photonic modes can significantly enhance the emission from fluorophores, resulting in a 52-fold improvement in signal intensity. The method is successfully applied to a sandwich immunoassay for human interleukin-6, achieving a detection limit three orders of magnitude lower than standard immunoassays.
Article
Chemistry, Multidisciplinary
Ji-Yang Zhou, Qiang Li, Zhi-He Hao, Wu-Xi Lin, Zhen-Xuan He, Rui-Jian Liang, Liping Guo, Hao Li, Lixing You, Jian-Shun Tang, Jin-Shi Xu, Chuan-Feng Li, Guang-Can Guo
Summary: Optically addressable spin defects in silicon carbide (SiC) have been enhanced in brightness and spin-control strength using surface plasmons generated by gold film coplanar waveguides. The mechanism of the plasmonic-enhanced effect has been studied by tuning the distance between defects and the gold film surface. A three-energy-level model is used to determine the corresponding transition rates and lifetime measurements verify the coupling between defects and surface plasmons. This low-cost scheme can be applied to other spin defects in different materials, promoting the development of spin-defect-based quantum applications in SiC materials.
Article
Nanoscience & Nanotechnology
Seemesh Bhaskar, Venkatesh Srinivasan, Sai Sathish Ramamurthy
Summary: The green synthesis of nanomaterials with multifaceted applications in photonics and biomedical fields is a difficult challenge. This study demonstrates a 1-minute, user-friendly, and eco-friendly green synthesis of Nd2O3-Ag nanohybrids with synergistic surface functionalities. The nanohybrids possess excellent bactericidal, fungicidal, antioxidant, and anticancer properties, and can be used for food hazard sensing. The proposed methodology has the potential for transdisciplinary nanophotonics and biomedical sensing applications.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Yue-Jiao Zhang, Petar M. Radjenovic, Xiao-Shun Zhou, Hua Zhang, Jian-Lin Yao, Jian-Feng Li
Summary: Plasmonic core-shell nanostructures have highly tunable optical properties, and when excited by an incident laser, generate strong and highly localized electromagnetic fields that significantly enhance excitation and/or radiation processes to amplify signals and improve spectroscopic sensitivity.
ADVANCED MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Min Liu, Lan Yu, Yanru Li, Ying Ma, Sha An, Juanjuan Zheng, Lixin Liu, Ke Lin, Peng Gao
Summary: This study presents a new configuration of metal-enhanced fluorescence (MEF) using a bionic nanorod array illuminated by a radially polarized vector beam (RVB), which significantly improves the fluorescence intensity. Results show that, with RVB excitation, the fluorescence intensity of the nanoimprinted substrate is more than 10 times stronger than that of glass, and the bionic nanoarray substrate has a fluorescence intensity approximately 2 times stronger with RVB compared to linearly polarized beam.
Article
Engineering, Biomedical
Wenzhen Pan, Zheng Li, Shang Qiu, Chengbai Dai, Shengyue Wu, Xin Zheng, Ming Guan, Fenglei Gao
Summary: A novel H-2 nanogenerator based on MOF loaded with polydopamine and Perovskite quantum dots was constructed, exhibiting potential in treating rheumatoid arthritis by overcoming the limitations of current therapies and showing anti-inflammatory effects.
MATERIALS TODAY BIO
(2022)
Review
Chemistry, Multidisciplinary
Dong Liu, Can Xue
Summary: Plasmonic photocatalysis is a promising approach for solar energy transformation, which can enhance photocatalytic efficiency by optimizing the composition, spacing, and orientation of metal nanostructures. Integrating metal nanostructures with semiconductor photocatalysts can accelerate exciton generation and separation, thus improving photocatalytic efficiency.
ADVANCED MATERIALS
(2021)
Article
Biochemical Research Methods
Wrenit Gem Pearl, Elena V. Perevedentseva, Artashes V. Karmenyan, Vitaly A. Khanadeev, Sheng-Yun Wu, Yuan-Ron Ma, Nikolai G. Khlebtsov, Chia-Liang Cheng
Summary: The study demonstrates the potential applications of gold nanostars in photothermal therapy and imaging by adjusting their plasmonic properties. Experimental results show that gold nanostars have low cytotoxicity on lung cancer cells, as well as high efficiency in temperature increase and irradiation-induced photothermal effect.
JOURNAL OF BIOPHOTONICS
(2022)
Article
Geriatrics & Gerontology
Jared M. Campbell, Saabah Mahbub, Abbas Habibalahi, Sharon Paton, Stan Gronthos, Ewa Goldys
Summary: The study used non-destructive multispectral assessment to investigate the metabolic mechanisms of in vitro mesenchymal stem cell (MSC) ageing. By analyzing spectral signals for different fluorophores in MSCs over serial passages, the researchers were able to develop a reliable model for categorizing the age of culture-expanded MSCs accurately.
Review
Biochemistry & Molecular Biology
Biyao Yang, Bo-Ping Song, Shaina Shankar, Anna Guller, Wei Deng
Summary: Liposomes, among various nanoparticle-based delivery platforms, have shown particular success in clinical applications, especially in cancer therapy like breast cancer. This review discusses liposome design with targeting and triggering functions, as well as recent advancements in liposome-based therapeutics for breast cancer since 2014. Challenges in the future clinical translation of liposome technology are also identified.
CELLULAR AND MOLECULAR LIFE SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Sandhya Clement, Anna Guller, Saabah B. Mahbub, Ewa M. Goldys
Summary: Radiodynamic therapy (RDT) is a promising non-invasive anti-cancer treatment that generates reactive oxygen species (ROS) through X-ray and a photosensitizer drug. A novel nanoparticle drug formulation for RDT, consisting of poly (lactic-co-glycolic acid) (PLGA) nanoparticles co-loaded with a photosensitizer drug verteporfin (VP) and an oxygen-carrying molecule, perfluorooctylbromide (PFOB), showed significant increase in ROS production under both normoxic and hypoxic conditions. RDT with these nanoparticles effectively killed pancreatic cancer cells and suppressed tumor cell outgrowth, demonstrating potential for treating deep-seated hypoxic tumors.
Article
Biochemistry & Molecular Biology
Sandhya Clement, Ayad G. Anwer, Layla Pires, Jared Campbell, Brian C. Wilson, Ewa M. Goldys
Summary: Radiodynamic therapy (RDT) is a therapy that uses high-energy X-rays instead of traditional photodynamic therapy, which can effectively treat deep-seated tumors. Studies have shown that incorporating a photosensitizer into polymer nanoparticles and targeting cell-penetrating peptides can enhance the effectiveness of RDT treatment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Engineering, Environmental
Yi Li, Fei Deng, Tim Hall, Graham Vesey, Ewa M. Goldys
Summary: This study introduces an ultrasensitive CRISPR/Cas12a-powered method for microbial detection, demonstrating the potential for water quality assessment and whole pathogen detection. The approach combines antibody-based recognition with CRISPR/Cas12a-based fluorescent signal amplification, enabling the detection of single Cryptosporidium parvum oocysts and showing promise for application in various complex sample matrices.
Correction
Multidisciplinary Sciences
Saabah B. Mahbub, Long T. Nguyen, Abbas Habibalahi, Jared M. Campbell, Ayad G. Anwer, Uzair M. Qadri, Anthony Gill, Angela Chou, Muh Geot Wong, Martin E. Gosnell, Carol A. Pollock, Sonia Saad, Ewa M. Goldys
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Saabah B. Mahbub, Long T. Nguyen, Abbas Habibalahi, Jared M. Campbell, Ayad G. Anwer, Uzair M. Qadri, Anthony Gill, Angela Chou, Muh Geot Wong, Martin E. Gosnell, Carol A. Pollock, Sonia Saad, Ewa M. Goldys
Summary: This study demonstrates the potential of multispectral assessment of cell autofluorescence in urinary exfoliated proximal tubule kidney cells as a sensitive, non-invasive diagnostic method for distinguishing healthy and diseased patients with CKD, showing significant differences in autofluorescence signals.
SCIENTIFIC REPORTS
(2021)
Article
Biochemical Research Methods
Vlada S. Rozova, Ayad G. Anwer, Anna E. Guller, Hamidreza Aboulkheyr Es, Zahra Khabir, Anastasiya Sokolova, Maxim U. Gavrilov, Ewa M. Goldys, Majid Ebrahimi Warkiani, Jean Paul Thiery, Andrei Zvyagin
Summary: The study used machine learning and image analysis to examine how individual breast cancer cells respond to substrates of varying stiffness, revealing significant changes in cell morphology and molecular expression. The results suggest that the stiffest microenvironment can induce MET, providing new insights into the process of metastasis.
PLOS COMPUTATIONAL BIOLOGY
(2021)
Article
Microbiology
Hari Kumar Peguda, Saabah B. Mahbub, Tashi Doma Sherpa, Dinesh Subedi, Abbas Habibalahi, Ayad G. Anwer, Zi Gu, Mark D. P. Willcox, Ewa M. Goldys, Nicole A. Carnt
Summary: This study investigated the effect of antibiotics and anesthetic drugs on the autofluorescence patterns of Acanthamoeba and bacteria that cause keratitis. Fluorescence spectroscopy was found to differentiate Acanthamoeba from bacteria in vitro, highlighting the potential for diagnostic use. Further research is needed to assess the fluorescence patterns of different strains and the effects of anti-amoebic drugs before in vivo testing.
Article
Obstetrics & Gynecology
Tiffany C. Y. Tan, Saabah B. Mahbub, Jared M. Campbell, Abbas Habibalahi, Carl A. Campugan, Ryan D. Rose, Darren J. X. Chow, Sanam Mustafa, Ewa M. Goldys, Kylie R. Dunning
Summary: The study successfully differentiated between euploid and aneuploid ICM cells in mouse blastocysts using hyperspectral autofluorescence microscopy. Further validation in human embryos is needed to confirm the approach's effectiveness.
HUMAN REPRODUCTION
(2022)
Article
Neurosciences
Martin E. Gosnell, Vasiliki Staikopoulos, Ayad G. Anwer, Saabah B. Mahbub, Mark R. Hutchinson, Sanam Mustafa, Ewa M. Goldys
Summary: This study successfully validated the feasibility of using hyperspectral autofluorescence imaging and deep learning techniques as a tool to differentiate tissues from nerve injured vs non-injured mice, providing important research and clinical applications prospects.
NEUROBIOLOGY OF DISEASE
(2021)
Article
Geriatrics & Gerontology
Jared M. Campbell, Saabah B. Mahbub, Michael J. Bertoldo, Abbas Habibalahi, Dale M. Goss, William L. Ledger, Robert B. Gilchrist, Lindsay E. Wu, Ewa M. Goldys
Summary: Increasing age has a negative impact on female fertility due to deteriorating quality of oocytes. The use of nicotinamide mononucleotide (NMN) has been shown to restore oocyte quality and fertility in aged animals. Identifying the multispectral profile of oocyte autofluorescence during aging could serve as a non-invasive and sensitive measure of oocyte quality.
Article
Oncology
Abbas Habibalahi, Alexandra Allende, Jesse Michael, Ayad G. Anwer, Jared Campbell, Saabah B. Mahbub, Chandra Bala, Minas T. Coroneo, Ewa M. Goldys
Summary: This study introduces an imaging-based method for screening ocular surface squamous neoplasia, which will reduce pressure on health resources and potentially eliminate the need for eye biopsy in suspected cases.
Meeting Abstract
Oncology
Anna Guller, Sandhya Clement, Benjamin Heng, Paul Sowman, Gilles Guillemin, Ewa Goldys
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY
(2021)
Meeting Abstract
Obstetrics & Gynecology
C. Y. Tan, S. B. Mahbub, C. A. Campugan, J. Campbell, A. Habibalahi, D. J. X. Chow, S. Mustafa, E. M. Goldys, K. R. Dunning
HUMAN REPRODUCTION
(2021)