Scintillation proximity assay (SPA) as a new approach to determine a ligand’s kinetic profile. A case in point for the adenosine A1 receptor
出版年份 2015 全文链接
标题
Scintillation proximity assay (SPA) as a new approach to determine a ligand’s kinetic profile. A case in point for the adenosine A1 receptor
作者
关键词
G protein-coupled receptors, Scintillation proximity assay, Binding kinetics, Adenosine A<sub>1</sub> receptor, Residence time
出版物
Purinergic Signalling
Volume 12, Issue 1, Pages 115-126
出版商
Springer Nature
发表日期
2015-12-09
DOI
10.1007/s11302-015-9485-0
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Real-time monitoring of binding events on a thermostabilized human A2A receptor embedded in a lipid bilayer by surface plasmon resonance
- (2015) Nicolas Bocquet et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Affinity and kinetics study of anthranilic acids as HCA2 receptor agonists
- (2015) Jacobus P.D. van Veldhoven et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Biosensor-based affinities and binding kinetics of small molecule antagonists to the adenosine A2Areceptor reconstituted in HDL like particles
- (2015) Elena Segala et al. FEBS LETTERS
- A study of the molecular mechanism of binding kinetics and long residence times of human CCR5 receptor small molecule allosteric ligands
- (2014) David C Swinney et al. BRITISH JOURNAL OF PHARMACOLOGY
- Binding Kinetics of ZM241385 Derivatives at the Human Adenosine A2AReceptor
- (2014) Dong Guo et al. ChemMedChem
- Drug-Target Residence Time-A Case for G Protein-Coupled Receptors
- (2014) Dong Guo et al. MEDICINAL RESEARCH REVIEWS
- Structure–Kinetic Relationships—An Overlooked Parameter in Hit-to-Lead Optimization: A Case of Cyclopentylamines as Chemokine Receptor 2 Antagonists
- (2013) Maris Vilums et al. JOURNAL OF MEDICINAL CHEMISTRY
- Functional efficacy of adenosine A2A receptor agonists is positively correlated to their receptor residence time
- (2012) Dong Guo et al. BRITISH JOURNAL OF PHARMACOLOGY
- Measuring substrate binding and affinity of purified membrane transport proteins using the scintillation proximity assay
- (2012) Daniel Harder et al. Nature Protocols
- Fused tricyclic pyrrolizinones that exhibit pseudo-irreversible blockade of the NK1 receptor
- (2010) Gregori J. Morriello et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Exploring the Mechanism of Agonist Efficacy: A Relationship between Efficacy and Agonist Dissociation Rate at the Muscarinic M3 Receptor
- (2009) D. A. Sykes et al. MOLECULAR PHARMACOLOGY
- Scintillation Proximity Assays in High-Throughput Screening
- (2008) J. Fraser Glickman et al. ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
- Residence Time of Receptor−Ligand Complexes and Its Effect on Biological Function
- (2008) Peter J. Tummino et al. BIOCHEMISTRY
- 5-Amino-6-chloro-N-[(1-isobutylpiperidin-4-yl)methyl]-2-methylimidazo[1,2- ]pyridine-8-carboxamide (CJ-033,466), a Novel and Selective 5-Hydroxytryptamine4 Receptor Partial Agonist: Pharmacological Profile in Vitro and Gastroprokinetic Effect in Conscious Dogs
- (2008) T. Mikami et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started