On-chip bioorthogonal chemistry enables immobilization of in situ modified nanoparticles and small molecules for label-free monitoring of protein binding and reaction kinetics

Dextran-Coated Iron Oxide Nanoparticles: A Versatile Platform for Targeted Molecular Imaging, Molecular Diagnostics, and Therapy

(2011) Carlos Tassa et al.   ACCOUNTS OF CHEMICAL RESEARCH

Bioconjugation with Strained Alkenes and Alkynes

(2011) Marjoke F. Debets et al.   ACCOUNTS OF CHEMICAL RESEARCH

Introducing Bioorthogonal Functionalities into Proteins in Living Cells

(2011) Ziyang Hao et al.   ACCOUNTS OF CHEMICAL RESEARCH

Biomedical Applications of Tetrazine Cycloadditions

(2011) Neal K. Devaraj et al.   ACCOUNTS OF CHEMICAL RESEARCH

The Evolution of the Protein Corona around Nanoparticles: A Test Study

(2011) Martin Lundqvist et al.   ACS Nano

Probing Intracellular Biomarkers and Mediators of Cell Activation Using Nanosensors and Bioorthogonal Chemistry

(2011) Jered B. Haun et al.   ACS Nano

Multiplexed Magnetic Labeling Amplification Using Oligonucleotide Hybridization

(2011) Monty Liong et al.   ADVANCED MATERIALS

Bioorthogonal Probes for Polo-like Kinase 1 Imaging and Quantification

(2011) Ghyslain Budin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dendrimer-Mediated Multivalent Binding for the Enhanced Capture of Tumor Cells

(2011) Ja Hye Myung et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Supramolecular Host-Guest Interaction for Labeling and Detection of Cellular Biomarkers

(2011) Sarit S. Agasti et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Specific Pathogen Detection Using Bioorthogonal Chemistry and Diagnostic Magnetic Resonance

(2011) Monty Liong et al.   BIOCONJUGATE CHEMISTRY

Synthesis and Evaluation of a Series of 1,2,4,5-Tetrazines for Bioorthogonal Conjugation

(2011) Mark R. Karver et al.   BIOCONJUGATE CHEMISTRY

High-Yielding, Two-Step18F Labeling Strategy for18F-PARP1 Inhibitors

(2011) Edmund J. Keliher et al.   ChemMedChem

A Bioorthogonal Quadricyclane Ligation

(2011) Ellen M. Sletten et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design and Synthesis of Highly Reactive Dienophiles for the Tetrazine–trans-Cyclooctene Ligation

(2011) Michael T. Taylor et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanoparticles versus the placenta

(2011) Jeffrey A. Keelan   Nature Nanotechnology

Comparative Study of Random and Oriented Antibody Immobilization Techniques on the Binding Capacity of Immunosensor

(2010) A. Kausaite-Minkstimiene et al.   ANALYTICAL CHEMISTRY

Readily Accessible Bicyclononynes for Bioorthogonal Labeling and Three-Dimensional Imaging of Living Cells

(2010) Jan Dommerholt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrokinetic label-free screening chip: a marriage of multiplexing and high throughput analysis using surface plasmon resonance imaging

(2010) Ganeshram Krishnamoorthy et al.   LAB ON A CHIP

Bioorthogonal chemistry amplifies nanoparticle binding and enhances the sensitivity of cell detection

(2010) Jered B. Haun et al.   Nature Nanotechnology

Hybrid PET-optical imaging using targeted probes

(2010) Matthias Nahrendorf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small Molecule Immunosensing Using Surface Plasmon Resonance

(2010) John Mitchell   SENSORS

Fast and Sensitive Pretargeted Labeling of Cancer Cells through a Tetrazine/trans-Cyclooctene Cycloaddition

(2009) Neal K. Devaraj et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Click Chemistry beyond Metal-Catalyzed Cycloaddition

(2009) C. Remzi Becer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

18F Labeled Nanoparticles forin VivoPET-CT Imaging

(2009) Neal K. Devaraj et al.   BIOCONJUGATE CHEMISTRY

Binding Affinity and Kinetic Analysis of Targeted Small Molecule-Modified Nanoparticles

(2009) Carlos Tassa et al.   BIOCONJUGATE CHEMISTRY

Specific or Nonspecific Protein-Polyphenol Interactions? Discrimination in Real Time by Surface Plasmon Resonance

(2009) Céline Douat-Casassus et al.   CHEMBIOCHEM

Unbiased discovery of in vivo imaging probes through in vitro profiling of nanoparticle libraries

(2009) Kimberly A. Kelly et al.   Integrative Biology

Identifying the proteins to which small-molecule probes and drugs bind in cells

(2009) S.-E. Ong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Surface Plasmon Resonance Assay for Chloramphenicol

(2008) Jing Yuan et al.   ANALYTICAL CHEMISTRY

Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging

(2008) Neal K. Devaraj et al.   BIOCONJUGATE CHEMISTRY

Surface Plasmon Resonance Based Assay for the Detection and Characterization of Promiscuous Inhibitors

(2008) Anthony M. Giannetti et al.   JOURNAL OF MEDICINAL CHEMISTRY

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

(2008) Melissa L. Blackman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

(2008) M. Lundqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vivo Imaging of Membrane-Associated Glycans in Developing Zebrafish

(2008) S. T. Laughlin et al.   SCIENCE