Oral simvastatin administration delays castration-resistant progression and reduces intratumoral steroidogenesis of LNCaP prostate cancer xenografts

A low carbohydrate, high protein diet suppresses intratumoral androgen synthesis and slows castration-resistant prostate tumor growth in mice

(2015) H. Bobby Fokidis et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Statin Use at the Time of Initiation of Androgen Deprivation Therapy and Time to Progression in Patients With Hormone-Sensitive Prostate Cancer

(2015) Lauren C. Harshman et al.   JAMA Oncology

New targets for resistant prostate cancer

(2015) Timothy C. Thompson et al.   Oncotarget

Cholesteryl Ester Accumulation Induced by PTEN Loss and PI3K/AKT Activation Underlies Human Prostate Cancer Aggressiveness

(2014) Shuhua Yue et al.   Cell Metabolism

Glioblastoma Multiforme Metastasis Outside the CNS: Three Case Reports and Possible Mechanisms of Escape

(2014) Jackson D. Hamilton et al.   JOURNAL OF CLINICAL ONCOLOGY

Effect of simvastatin on castration-resistant prostate cancer cells

(2014) Jenny Kim et al.   Lipids in Health and Disease

Anticancer Activity of a Novel Selective CYP17A1 Inhibitor in Preclinical Models of Castrate-Resistant Prostate Cancer

(2014) P. J. Toren et al.   MOLECULAR CANCER THERAPEUTICS

Evolution of androgen receptor targeted therapy for advanced prostate cancer

(2014) Yien Ning Sophia Wong et al.   Nature Reviews Clinical Oncology

Current Approaches, Challenges and Future Directions for Monitoring Treatment Response in Prostate Cancer

(2014) T.J. Wallace et al.   Journal of Cancer

TAK-441, a novel investigational smoothened antagonist, delays castration-resistant progression in prostate cancer by disrupting paracrine hedgehog signaling

(2013) Naokazu Ibuki et al.   INTERNATIONAL JOURNAL OF CANCER

Statin Use in Relation to Prostate Cancer Outcomes in a Population-based Patient Cohort Study

(2013) Milan S. Geybels et al.   PROSTATE

Impact of Circulating Cholesterol Levels on Growth and Intratumoral Androgen Concentration of Prostate Tumors

(2012) Elahe A. Mostaghel et al.   PLoS One

Statin Use and Risk of Prostate Cancer: A Meta-Analysis of Observational Studies

(2012) Dipika Bansal et al.   PLoS One

Statin use and fatal prostate cancer

(2011) Stephen W. Marcella et al.   CANCER

Statins and prostate cancer: Molecular and clinical aspects

(2011) Georgios Papadopoulos et al.   EUROPEAN JOURNAL OF CANCER

Clinical and Biochemical Consequences of CYP17A1 Inhibition with Abiraterone Given with and without Exogenous Glucocorticoids in Castrate Men with Advanced Prostate Cancer

(2011) Gerhardt Attard et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Statins and Prostate Cancer Diagnosis and Grade in a Veterans Population

(2011) W. R. Farwell et al.   JNCI-Journal of the National Cancer Institute

Atorvastatin and Celecoxib in Combination Inhibits the Progression of Androgen-Dependent LNCaP Xenograft Prostate Tumors to Androgen Independence

(2010) X. Zheng et al.   Cancer Prevention Research

Metabolomic Characterization of Human Prostate Cancer Bone Metastases Reveals Increased Levels of Cholesterol

(2010) Elin Thysell et al.   PLoS One

Androgen Levels Increase by Intratumoral De novo Steroidogenesis during Progression of Castration-Resistant Prostate Cancer

(2008) J. A. Locke et al.   CANCER RESEARCH

Maintenance of Intratumoral Androgens in Metastatic Prostate Cancer: A Mechanism for Castration-Resistant Tumor Growth

(2008) R. B. Montgomery et al.   CANCER RESEARCH

Statin use and the risk of prostate cancer: A metaanalysis of 6 randomized clinical trials and 13 observational studies

(2008) Stefanos Bonovas et al.   INTERNATIONAL JOURNAL OF CANCER

Do the cholesterol-lowering properties of statins affect cancer risk?

(2008) Keith R. Solomon et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM