TAK-441, a novel investigational smoothened antagonist, delays castration-resistant progression in prostate cancer by disrupting paracrine hedgehog signaling
出版年份 2013 全文链接
标题
TAK-441, a novel investigational smoothened antagonist, delays castration-resistant progression in prostate cancer by disrupting paracrine hedgehog signaling
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF CANCER
Volume 133, Issue 8, Pages 1955-1966
出版商
Wiley
发表日期
2013-04-06
DOI
10.1002/ijc.28193
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Repurposing Itraconazole as a Treatment for Advanced Prostate Cancer: A Noncomparative Randomized Phase II Trial in Men With Metastatic Castration-Resistant Prostate Cancer
- (2013) E. S. Antonarakis et al. ONCOLOGIST
- Small molecule inhibitors of the hedgehog signaling pathway for the treatment of cancer
- (2012) Jeong In Yun et al. ARCHIVES OF PHARMACAL RESEARCH
- Hedgehog signaling in myofibroblasts directly promotes prostate tumor cell growth
- (2012) Maribella Domenech et al. Integrative Biology
- Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma
- (2012) Chad M. McKee et al. JOURNAL OF CLINICAL INVESTIGATION
- Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study
- (2012) Karim Fizazi et al. LANCET ONCOLOGY
- Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy
- (2012) Howard I. Scher et al. NEW ENGLAND JOURNAL OF MEDICINE
- Hedgehog Signaling Inhibition Blocks Growth of Resistant Tumors through Effects on Tumor Microenvironment
- (2011) E. Heller et al. CANCER RESEARCH
- Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells
- (2011) Mengqian Chen et al. CELL CYCLE
- Expression of hedgehog pathway components in prostate carcinoma microenvironment: shifting the balance towards autocrine signalling
- (2011) Vassiliki Tzelepi et al. HISTOPATHOLOGY
- Androgens regulate Hedgehog signalling and proliferation in androgen-dependent prostate cells
- (2011) Nanor Sirab et al. INTERNATIONAL JOURNAL OF CANCER
- Canonical hedgehog signaling augments tumor angiogenesis by induction of VEGF-A in stromal perivascular cells
- (2011) W. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Active sonic hedgehog signaling between androgen independent human prostate cancer cells and normal/benign but not cancer-associated prostate stromal cells
- (2011) Katsumi Shigemura et al. PROSTATE
- Common Botanical Compounds Inhibit the Hedgehog Signaling Pathway in Prostate Cancer
- (2010) A. Slusarz et al. CANCER RESEARCH
- Review: Targeting the Hedgehog pathway in cancer
- (2010) Sachin Gupta et al. Therapeutic Advances in Medical Oncology
- Recent patents for Hedgehog pathway inhibitors for the treatment of malignancy
- (2009) Martin R Tremblay et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449
- (2009) Charles M. Rudin et al. NEW ENGLAND JOURNAL OF MEDICINE
- Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma
- (2009) Daniel D. Von Hoff et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Sonic Hedgehog pathway stimulates prostate tumor growth by paracrine signaling and recapitulates embryonic gene expression in tumor myofibroblasts
- (2009) A Shaw et al. ONCOGENE
- Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis
- (2009) H. Tian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanisms of Hedgehog pathway activation in cancer and implications for therapy
- (2009) Suzie J. Scales et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo)
- (2008) Xiaomei Zhang et al. BREAST CANCER RESEARCH AND TREATMENT
- Inhibition of androgen-independent prostate cancer cell growth is enhanced by combination therapy targeting Hedgehog and ErbB signalling
- (2008) Greg Shaw et al. Cancer Cell International
- GLI2 Knockdown Using an Antisense Oligonucleotide Induces Apoptosis and Chemosensitizes Cells to Paclitaxel in Androgen-Independent Prostate Cancer
- (2008) S. Narita et al. CLINICAL CANCER RESEARCH
- Comparative expression of Hedgehog ligands at different stages of prostate carcinoma progression
- (2008) S Azoulay et al. JOURNAL OF PATHOLOGY
- A paracrine requirement for hedgehog signalling in cancer
- (2008) Robert L. Yauch et al. NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now