HIV-1 Tat Protein Induces PD-L1 (B7-H1) Expression on Dendritic Cells through Tumor Necrosis Factor Alpha- and Toll-Like Receptor 4-Mediated Mechanisms

Early Resolution of Acute Immune Activation and Induction of PD-1 in SIV-Infected Sooty Mangabeys Distinguishes Nonpathogenic from Pathogenic Infection in Rhesus Macaques

(2014) J. D. Estes et al.   JOURNAL OF IMMUNOLOGY

Dendritic cell dysregulation during HIV-1 infection

(2013) Elizabeth Miller et al.   IMMUNOLOGICAL REVIEWS

Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

(2013) Omid Hamid et al.   NEW ENGLAND JOURNAL OF MEDICINE

HIV-1 Tat Protein Induces the Production of IDO in Human Monocyte Derived-Dendritic Cells through a Direct Mechanism: Effect on T Cells Proliferation

(2013) Rémi Planès et al.   PLoS One

HIV-1 Tat protein binds to TLR4-MD2 and signals to induce TNF-α and IL-10

(2013) Nawal Ben Haij et al.   Retrovirology

Molecular signatures of T-cell inhibition in HIV-1 infection

(2013) Marie Larsson et al.   Retrovirology

Monitoring cellular immune markers in HIV infection

(2013) Delphine Sauce et al.   Current Opinion in HIV and AIDS

HIV-1 Pathogenesis: The Virus

(2013) R. Swanstrom et al.   Cold Spring Harbor Perspectives in Medicine

Kinetics of Myeloid Dendritic Cell Trafficking and Activation: Impact on Progressive, Nonprogressive and Controlled SIV Infections

(2013) Viskam Wijewardana et al.   PLoS Pathogens

Innate Immune Sensing of HIV-1 by Dendritic Cells

(2012) Jeremy Luban   Cell Host & Microbe

The paradox of the immune response in HIV infection: When inflammation becomes harmful

(2012) Hayley Ipp et al.   CLINICA CHIMICA ACTA

Soluble mediators of inflammation in HIV and their implications for therapeutics and vaccine development

(2012) Sheila M. Keating et al.   CYTOKINE & GROWTH FACTOR REVIEWS

PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques

(2012) Ravi Dyavar Shetty et al.   JOURNAL OF CLINICAL INVESTIGATION

In Vivo Blockade of the PD-1 Receptor Suppresses HIV-1 Viral Loads and Improves CD4+ T Cell Levels in Humanized Mice

(2012) B. E. Palmer et al.   JOURNAL OF IMMUNOLOGY

Blocking of PDL-1 Interaction Enhances Primary and Secondary CD8 T Cell Response to Herpes Simplex Virus-1 Infection

(2012) Rudragouda Channappanavar et al.   PLoS One

The Herpes Simplex Virus Type 1 Latency-Associated Transcript Inhibits Phenotypic and Functional Maturation of Dendritic Cells

(2012) Aziz Alami Chentoufi et al.   VIRAL IMMUNOLOGY

Tits and bits of HIV Tat protein

(2011) Manish K Johri et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo

(2011) Melissa Swiecki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Herpes Simplex Virus 1 Latency-Associated Transcript Promotes Functional Exhaustion of Virus-Specific CD8+ T Cells in Latently Infected Trigeminal Ganglia: a Novel Immune Evasion Mechanism

(2011) A. A. Chentoufi et al.   JOURNAL OF VIROLOGY

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(2011) Esaki Shankar et al.   MOLECULAR MEDICINE

The Cytokine Network of Acute HIV Infection: A Promising Target for Vaccines and Therapy to Reduce Viral Set-Point?

(2011) Peter D. Katsikis et al.   PLoS Pathogens

Increased B7-H1 Expression on Dendritic Cells Correlates with Programmed Death 1 Expression on T Cells in Simian Immunodeficiency Virus-Infected Macaques and May Contribute to T Cell Dysfunction and Disease Progression

(2010) H. Xu et al.   JOURNAL OF IMMUNOLOGY

Increased PD-L1 expression and PD-L1/CD86 ratio on dendritic cells were associated with impaired dendritic cells function in HCV infection

(2010) Tao Shen et al.   JOURNAL OF MEDICAL VIROLOGY

Human immunodeficiency virus type 1 clade B and C Tat differentially induce indoleamine 2,3-dioxygenase and serotonin in immature dendritic cells: Implications for neuroAIDS

(2010) Thangavel Samikkannu et al.   JOURNAL OF NEUROVIROLOGY

A look behind closed doors: interaction of persistent viruses with dendritic cells

(2010) Mélanie Lambotin et al.   NATURE REVIEWS MICROBIOLOGY

Tryptophan Catabolism by Indoleamine 2,3-Dioxygenase 1 Alters the Balance of TH17 to Regulatory T Cells in HIV Disease

(2010) D. Favre et al.   Science Translational Medicine

Early Myeloid Dendritic Cell Dysregulation is Predictive of Disease Progression in Simian Immunodeficiency Virus Infection

(2010) Viskam Wijewardana et al.   PLoS Pathogens

Revisiting Immune Exhaustion During HIV Infection

(2010) Alka Khaitan et al.   Current HIV/AIDS Reports

Differential Regulation of Indoleamine-2,3-Dioxygenase (IDO) by HIV Type 1 Clade B and C Tat Protein

(2009) Thangavel Samikkannu et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Differential Effects of HIV Type 1 Clade B and Clade C Tat Protein on Expression of Proinflammatory and Antiinflammatory Cytokines by Primary Monocytes

(2009) Nimisha Gandhi et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells

(2009) M. A. Brockman et al.   BLOOD

HIV-1 Clade B Tat, but Not Clade C Tat, Increases X4 HIV-1 Entry into Resting but Not Activated CD4+T Cells

(2009) Grant R. Campbell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1 Tat Addresses Dendritic Cells to Induce a Predominant Th1-Type Adaptive Immune Response That Appears Prevalent in the Asymptomatic Stage of Infection

(2009) E. Fanales-Belasio et al.   JOURNAL OF IMMUNOLOGY

PD-1 and Its Ligands in Tolerance and Immunity

(2008) Mary E. Keir et al.   Annual Review of Immunology

HIV-1 Tat protein induces IL-10 production by an alternative TNF-α-independent pathway in monocytes: Role of PKC-δ and p38 MAP kinase

(2008) Kaoutar Leghmari et al.   CELLULAR IMMUNOLOGY

HIV-1 Tat protein induces IL-10 production in monocytes by classical and alternative NF-κB pathways

(2008) K LEGHMARI et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

B7-H1 up-regulation impairs myeloid DC and correlates with disease progression in chronic HIV-1 infection

(2008) Xicheng Wang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Modulation of dendritic cell function by persistent viruses

(2008) B. Liu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Enhancing SIV-specific immunity in vivo by PD-1 blockade

(2008) Vijayakumar Velu et al.   NATURE

Structures of PD-1 with its ligands: Sideways and dancing cheek to cheek

(2008) G. J. Freeman   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immune activation and inflammation in HIV-1 infection: causes and consequences

(2007) V Appay et al.   JOURNAL OF PATHOLOGY