Human Coagulation Factor X-Adenovirus Type 5 Complexes Poorly Stimulate an Innate Immune Response in Human Mononuclear Phagocytes

Genomic responses in mouse models greatly mimic human inflammatory diseases

(2014) Keizo Takao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Comparative Review of Toll-Like Receptor 4 Expression and Functionality in Different Animal Species

(2014) Céline Vaure et al.   Frontiers in Immunology

Serum Amyloid A3 Binds MD-2 To Activate p38 and NF- B Pathways in a MyD88-Dependent Manner

(2013) A. Deguchi et al.   JOURNAL OF IMMUNOLOGY

Corrective GUSB Transfer to the Canine Mucopolysaccharidosis VII Brain

(2013) Aurelie Cubizolle et al.   MOLECULAR THERAPY

Coagulation factor X shields adenovirus type 5 from attack by natural antibodies and complement

(2013) Zhili Xu et al.   NATURE MEDICINE

Conservation and divergence in the transcriptional programs of the human and mouse immune systems

(2013) T. Shay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate immune response after adenoviral gene delivery into skin is mediated by AIM2, NALP3, DAI and mda5

(2013) Matthias Schulte et al.   SpringerPlus

Interaction between Mouse Adenovirus Type 1 and Cell Surface Heparan Sulfate Proteoglycans

(2012) Liesbeth Lenaerts et al.   PLoS One

Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2

(2012) U. Ohto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages

(2012) K. Schroder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coagulation Factor X Activates Innate Immunity to Human Species C Adenovirus

(2012) K. Doronin et al.   SCIENCE

Respiratory Syncytial Virus Fusion Protein-Induced Toll-Like Receptor 4 (TLR4) Signaling Is Inhibited by the TLR4 Antagonists Rhodobacter sphaeroides Lipopolysaccharide and Eritoran (E5564) and Requires Direct Interaction with MD-2

(2012) P. Rallabhandi et al.   mBio

CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

(2011) Ivan Zanoni et al.   CELL

Differential Effects of Murine and Human Factor X on Adenovirus Transduction via Cell-surface Heparan Sulfate

(2011) Anne K. Zaiss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA Expression Profiles of Human Blood Monocyte-derived Dendritic Cells and Macrophages Reveal miR-511 as Putative Positive Regulator of Toll-like Receptor 4

(2011) Liina Tserel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysosomal localization and mechanism of membrane penetration influence nonenveloped virus activation of the NLRP3 inflammasome

(2011) A.U. Barlan et al.   VIROLOGY

An ex vivo loop system models the toxicity and efficacy of PEGylated and unmodified adenovirus serotype 5 in whole human blood

(2010) A Danielsson et al.   GENE THERAPY

Adenovirus Membrane Penetration Activates the NLRP3 Inflammasome

(2010) A. U. Barlan et al.   JOURNAL OF VIROLOGY

Novel Roles of Lysines 122, 125, and 58 in Functional Differences between Human and Murine MD-2

(2009) J. Vasl et al.   JOURNAL OF IMMUNOLOGY

Lipopolysaccharide Stimulates Platelet Secretion and Potentiates Platelet Aggregation via TLR4/MyD88 and the cGMP-Dependent Protein Kinase Pathway

(2009) G. Zhang et al.   JOURNAL OF IMMUNOLOGY

The Cell Adhesion Molecule “CAR” and Sialic Acid on Human Erythrocytes Influence Adenovirus In Vivo Biodistribution

(2009) Elena Seiradake et al.   PLoS Pathogens

Adenovirus Serotype 5 Hexon Mediates Liver Gene Transfer

(2008) Simon N. Waddington et al.   CELL

Differential Activation of Human and Mouse Toll-Like Receptor 4 by the Adjuvant Candidate LpxL1 of Neisseria meningitidis

(2008) L. Steeghs et al.   INFECTION AND IMMUNITY

Activation of a dendritic cell–T cell axis by Ad5 immune complexes creates an improved environment for replication of HIV in T cells

(2008) Matthieu Perreau et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mouse adenovirus type 1 and human adenovirus type 5 differ in endothelial cell tropism and liver targeting

(2008) Liesbeth Lenaerts et al.   JOURNAL OF GENE MEDICINE

The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase

(2008) Sachie Hiratsuka et al.   NATURE CELL BIOLOGY

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

(2008) Jonathan C Kagan et al.   NATURE IMMUNOLOGY

Expression and function of Toll-like receptors on dendritic cells and other antigen presenting cells from non-human primates

(2008) Chutitorn Ketloy et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY