Rad51 recombinase prevents Mre11 nuclease-dependent degradation and excessive PrimPol-mediated elongation of nascent DNA after UV irradiation

FANCD2, FANCJ and BRCA2 cooperate to promote replication fork recovery independently of the Fanconi Anemia core complex

(2015) Maya Raghunandan et al.   CELL CYCLE

Roles of mutagenic translesion synthesis in mammalian genome stability, health and disease

(2015) Jacob G. Jansen et al.   DNA REPAIR

Alternative solutions and new scenarios for translesion DNA synthesis by human PrimPol

(2015) María I. Martínez-Jiménez et al.   DNA REPAIR

DNA2 drives processing and restart of reversed replication forks in human cells

(2015) Saravanabhavan Thangavel et al.   JOURNAL OF CELL BIOLOGY

Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells

(2015) Ralph Zellweger et al.   JOURNAL OF CELL BIOLOGY

Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repair

(2015) Julien Lafrance-Vanasse et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Gap-filling and bypass at the replication fork are both active mechanisms for tolerance of low-dose ultraviolet-induced DNA damage in the human genome

(2014) Annabel Quinet et al.   DNA REPAIR

CtIP mediates replication fork recovery in a FANCD2-regulated manner

(2014) Jung Eun Yeo et al.   HUMAN MOLECULAR GENETICS

DNA2 Cooperates with the WRN and BLM RecQ Helicases to Mediate Long-range DNA End Resection in Human Cells

(2014) Andreas Sturzenegger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FANCD2-Controlled Chromatin Access of the Fanconi-Associated Nuclease FAN1 Is Crucial for the Recovery of Stalled Replication Forks

(2014) I. Chaudhury et al.   MOLECULAR AND CELLULAR BIOLOGY

BRCA2 and RAD51 Promote Double-Strand Break Formation and Cell Death in Response to Gemcitabine

(2014) R. M. Jones et al.   MOLECULAR CANCER THERAPEUTICS

Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components

(2014) Constance Alabert et al.   NATURE CELL BIOLOGY

Rad51 Regulates Cell Cycle Progression by Preserving G2/M Transition in Mouse Embryonic Stem Cells

(2014) Sang-Wook Yoon et al.   STEM CELLS AND DEVELOPMENT

BRCA1 haploinsufficiency for replication stress suppression in primary cells

(2014) Shailja Pathania et al.   Nature Communications

Nonenzymatic Role for WRN in Preserving Nascent DNA Strands after Replication Stress

(2014) Fengtao Su et al.   Cell Reports

DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation

(2013) Rémy Bétous et al.   EMBO JOURNAL

Rad51 replication fork recruitment is required for DNA damage tolerance

(2013) Román González-Prieto et al.   EMBO JOURNAL

Oncogenes induce genotoxic stress by mitotic processing of unusual replication intermediates

(2013) Kai J. Neelsen et al.   JOURNAL OF CELL BIOLOGY

PrimPol Bypasses UV Photoproducts during Eukaryotic Chromosomal DNA Replication

(2013) Julie Bianchi et al.   MOLECULAR CELL

PrimPol, an Archaic Primase/Polymerase Operating in Human Cells

(2013) Sara García-Gómez et al.   MOLECULAR CELL

DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities

(2013) Atsushi Shibata et al.   MOLECULAR CELL

Repriming of DNA synthesis at stalled replication forks by human PrimPol

(2013) Silvana Mourón et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery

(2013) Indrajit Chaudhury et al.   NUCLEIC ACIDS RESEARCH

UV-triggered p21 degradation facilitates damaged-DNA replication and preserves genomic stability

(2013) S. F. Mansilla et al.   NUCLEIC ACIDS RESEARCH

MRX protects fork integrity at protein–DNA barriers, and its absence causes checkpoint activation dependent on chromatin context

(2013) Iben B. Bentsen et al.   NUCLEIC ACIDS RESEARCH

Spontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells

(2013) T. Wilhelm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repair of Strand Breaks by Homologous Recombination

(2013) M. Jasin et al.   Cold Spring Harbor Perspectives in Biology

A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2

(2012) Katharina Schlacher et al.   CANCER CELL

Abstract 2814: Potent and selective small molecule inhibitors of polo-like kinase 1: Biological characterization

(2012) Sheelagh Frame et al.   CANCER RESEARCH

Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA

(2012) J. Speroni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11

(2011) Katharina Schlacher et al.   CELL

The response of mammalian cells to UV-light reveals Rad54-dependent and independent pathways of homologous recombination

(2011) Berina Eppink et al.   DNA REPAIR

Brca2, Rad51 and Mre11: Performing balancing acts on replication forks

(2011) Vincenzo Costanzo   DNA REPAIR

Dysregulation of DNA polymerase κ recruitment to replication forks results in genomic instability

(2011) Mathew JK Jones et al.   EMBO JOURNAL

RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks

(2011) Yoshitami Hashimoto et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

UV stalled replication forks restart by re-priming in human fibroblasts

(2011) Ingegerd Elvers et al.   NUCLEIC ACIDS RESEARCH

Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair

(2010) Eva Petermann et al.   MOLECULAR CELL

Rad51 protects nascent DNA from Mre11-dependent degradation and promotes continuous DNA synthesis

(2010) Yoshitami Hashimoto et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination

(2009) Helen E Bryant et al.   EMBO JOURNAL

The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart

(2009) A. Ciccia et al.   GENES & DEVELOPMENT

FANCI Binds Branched DNA and Is Monoubiquitinated by UBE2T-FANCL

(2009) Simonne Longerich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Roles for DNA Polymerases Eta, Zeta, and REV1 in Lesion Bypass of Intrastrand versus Interstrand DNA Cross-Links

(2009) J. K. Hicks et al.   MOLECULAR AND CELLULAR BIOLOGY

Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells

(2009) Emilie Rass et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Repair of gaps opposite lesions by homologous recombination in mammalian cells

(2009) S. Adar et al.   NUCLEIC ACIDS RESEARCH

The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences In Vivo

(2009) Cyril Ribeyre et al.   PLoS Genetics

Reduced efficiency and increased mutagenicity of translesion DNA synthesis across a TT cyclobutane pyrimidine dimer, but not a TT 6-4 photoproduct, in human cells lacking DNA polymerase η

(2008) A HENDEL et al.   DNA REPAIR

Role of DNA polymerases η, ι and ζ in UV resistance and UV-induced mutagenesis in a human cell line

(2008) Quentin Gueranger et al.   DNA REPAIR

PCNA Ubiquitination and REV1 Define Temporally Distinct Mechanisms for Controlling Translesion Synthesis in the Avian Cell Line DT40

(2008) Charlotte E. Edmunds et al.   MOLECULAR CELL

Replication fork movement sets chromatin loop size and origin choice in mammalian cells

(2008) Sylvain Courbet et al.   NATURE

A homologous recombination defect affects replication-fork progression in mammalian cells

(2007) F. Daboussi et al.   JOURNAL OF CELL SCIENCE