NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets

Tissue-specific expression of the NOD-like receptor protein 3 in BALB/c mice

(2014) Zhiqiang Huang et al.   Journal of Veterinary Science

K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5

(2014) Kuzhuvelil B Harikumar et al.   NATURE IMMUNOLOGY

Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet

(2013) Islam N. Mohamed et al.   DIABETOLOGIA

Obesity phenotype is related to NLRP3 inflammasome activity and immunological profile of visceral adipose tissue

(2013) Nathalie Esser et al.   DIABETOLOGIA

TLR9 Deficiency Promotes CD73 Expression in T Cells and Diabetes Protection in Nonobese Diabetic Mice

(2013) N. Tai et al.   JOURNAL OF IMMUNOLOGY

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

(2013) Tony Jourdan et al.   NATURE MEDICINE

Toll-Like Receptor 4 Deficiency Accelerates the Development of Insulin-Deficient Diabetes in Non-Obese Diabetic Mice

(2013) Elke Gülden et al.   PLoS One

Polimorphisms in Inflammasome Genes Are Involved in the Predisposition to Systemic Lupus Erythematosus

(2012) Alessandra Pontillo et al.   AUTOIMMUNITY

NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis

(2012) M. Inoue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synergistic Reversal of Type 1 Diabetes in NOD Mice With Anti-CD3 and Interleukin-1 Blockade: Evidence of Improved Immune Regulation

(2011) V. Ablamunits et al.   DIABETES

Expression and Regulation of Chemokines in Murine and Human Type 1 Diabetes

(2011) S. A. Sarkar et al.   DIABETES

In vivo diabetogenic action of CD4+ T lymphocytes requires Fas expression and is independent of IL-1 and IL-18

(2011) Li Wen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TLR2 signaling improves immunoregulation to prevent type 1 diabetes

(2011) Christophe M. Filippi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-18 is required for self-reactive T cell expansion in NOD mice

(2011) Annette M. Marleau et al.   JOURNAL OF AUTOIMMUNITY

Differential Expression of NLRP3 among Hematopoietic Cells

(2011) G. Guarda et al.   JOURNAL OF IMMUNOLOGY

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

(2011) Bolormaa Vandanmagsar et al.   NATURE MEDICINE

Two SNPs inNLRP3gene are involved in the predisposition to type-1 diabetes and celiac disease in a pediatric population from northeast Brazil

(2010) A. Pontillo et al.   AUTOIMMUNITY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

NLRP3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th1 and Th17 Responses

(2010) D. Gris et al.   JOURNAL OF IMMUNOLOGY

The Role of Toll-Like Receptors 3 and 9 in the Development of Autoimmune Diabetes in NOD Mice

(2009) F. Susan Wong et al.   Annals of the New York Academy of Sciences

Inflammatory Role of ASC in Antigen-Induced Arthritis Is Independent of Caspase-1, NALP-3, and IPAF

(2009) L. Kolly et al.   JOURNAL OF IMMUNOLOGY

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

(2009) Mark D. Pescovitz et al.   NEW ENGLAND JOURNAL OF MEDICINE

A coding polymorphism in NALP1 confers risk for autoimmune Addison's disease and type 1 diabetes

(2008) N F Magitta et al.   GENES AND IMMUNITY

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

(2008) Li Wen et al.   NATURE