Exogenous Hsp70 delays senescence and improves cognitive function in aging mice

Gene expression changes in response to aging compared to heat stress, oxidative stress and ionizing radiation in Drosophila melanogaster

(2016) Gary Landis et al.   Aging-US

The age related markers lipofuscin and apoptosis show different genetic architecture by QTL mapping in short-lived Nothobranchius fish

(2016) Enoch Ng'oma et al.   Aging-US

Lifespan of mice and primates correlates with immunoproteasome expression

(2015) Andrew M. Pickering et al.   JOURNAL OF CLINICAL INVESTIGATION

The Fate of Exogenous Human HSP70 Introduced into Animal Cells by Different Means

(2015) Marina Yurinskaya et al.   Current Drug Delivery

A neuronal aging pattern unique to humans and common chimpanzees

(2014) Emmanuel P. Gilissen et al.   Brain Structure & Function

Developmental Sculpting of Intracortical Circuits by MHC Class I H2-Db and H2-Kb

(2014) Jaimie D. Adelson et al.   CEREBRAL CORTEX

Accumulation of modified proteins and aggregate formation in aging

(2014) Kerstin Nowotny et al.   EXPERIMENTAL GERONTOLOGY

Proteostasis and the Aging Proteome in Health and Disease

(2014) R. I. Morimoto et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Relationship between heat shock protein 70 expression and life span in Daphnia

(2014) Charles Schumpert et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Heat shock proteins in neurodegenerative disorders and aging

(2014) Rehana K. Leak   Journal of Cell Communication and Signaling

Molecular Chaperone Functions in Protein Folding and Proteostasis

(2013) Yujin E. Kim et al.   Annual Review of Biochemistry

Proteasomes in the brain of β2-microglobulin knockout mice

(2013) Yu. V. Lyupina et al.   BIOCHEMISTRY-MOSCOW

XBP-1 Is a Cell-Nonautonomous Regulator of Stress Resistance and Longevity

(2013) Rebecca C. Taylor et al.   CELL

Regulation of Organismal Proteostasis by Transcellular Chaperone Signaling

(2013) Patricija van Oosten-Hawle et al.   CELL

The long-term effects of a life-prolonging heat treatment on the Drosophila melanogaster transcriptome suggest that heat shock proteins extend lifespan

(2013) P. Sarup et al.   EXPERIMENTAL GERONTOLOGY

Stress proteins in aging and life span

(2013) Ayesha Murshid et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Mixed Proteasomes Function To Increase Viral Peptide Diversity and Broaden Antiviral CD8+ T Cell Responses

(2013) D. Zanker et al.   JOURNAL OF IMMUNOLOGY

Hsp72, inflammation, and aging: causes, consequences, and perspectives

(2012) Eduardo Ortega et al.   Annals of the New York Academy of Sciences

Hydra, the everlasting embryo, confronts aging

(2012) Daniel E. Martínez et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Recombinant human Hsp70 protects against lipoteichoic acid-induced inflammation manifestations at the cellular and organismal levels

(2011) Maxim Vinokurov et al.   CELL STRESS & CHAPERONES

Regulation of survival gene hsp70

(2011) Jordan Thomas Silver et al.   CELL STRESS & CHAPERONES

Antioxidant protection: A promising therapeutic intervention in neurodegenerative disease

(2011) Nilanjan Ghosh et al.   FREE RADICAL RESEARCH

Higher levels of heat shock proteins in longer-lived mammals and birds

(2011) Kurtis D. Salway et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Neuronal circuitry regulates the response of Caenorhabditis elegans to misfolded proteins

(2011) V. Prahlad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-related decreases in SYN levels associated with increases in MAP-2, apoE, and GFAP levels in the rhesus macaque prefrontal cortex and hippocampus

(2010) Gwendolen E. Haley et al.   AGE

Exogenous mammalian extracellular HSP70 reduces endotoxin manifestations at the cellular and organism levels

(2010) Elena Rozhkova et al.   Annals of the New York Academy of Sciences

Inhibition of Respiration Extends C. elegans Life Span via Reactive Oxygen Species that Increase HIF-1 Activity

(2010) Seung-Jae Lee et al.   CURRENT BIOLOGY

Exogenous protein Hsp70/Hsc70 can penetrate into brain structures and attenuate the severity of chemically-induced seizures

(2010) Irina V. Ekimova et al.   JOURNAL OF NEUROCHEMISTRY

Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathology

(2010) Thomas Kirkegaard et al.   NATURE

Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules

(2010) B. Guillaume et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Shock of Aging: Molecular Chaperones and the Heat Shock Response in Longevity and Aging – A Mini-Review

(2009) Stuart K. Calderwood et al.   GERONTOLOGY

Chaperokine Function of Recombinant Hsp72 Produced in Insect Cells Using a Baculovirus Expression System Is Retained

(2009) Hongying Zheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MHC Class I: An Unexpected Role in Neuronal Plasticity

(2009) Carla J. Shatz   NEURON

Interactive association of heat shock protein 70 genes variants with natural longevity in Xinjiang Hetian Uygur ethnicity

(2009) Jinxin Li et al.   Translational Research

Integrating the stress response: lessons for neurodegenerative diseases from C. elegans

(2008) Veena Prahlad et al.   TRENDS IN CELL BIOLOGY