Article
Biochemistry & Molecular Biology
Qinge Ma, Yang Guan, Zhipei Sang, Jianghong Dong, Rongrui Wei
Summary: This study isolated several compounds with hepatoprotective and hypolipidemic properties from the fruits of Hippophae rhamnoides L. using a bioassay-guided approach. The structures and activities of these compounds were extensively analyzed and discussed.
Article
Plant Sciences
Yajing Gu, Xinxin Wang, Fang Liu, Jin Zhang, Xiufang Zhang, Jiping Liu, Sijia Li, Decheng Wang, Hongquan Guan, Diandong Hou
Summary: The present study investigated the effects of total flavonoids of Hippophae rhamnoides (TFH) on MC903-induced atopic dermatitis (AD)-like lesions in mice. TFH showed anti-inflammatory and immunomodulatory effects by regulating Th1/Th2 balance, inhibiting mast cell infiltration, and promoting the expression of filaggrin (FLG). TFH also reduced the expressions of cytokines and signaling proteins related to inflammation and repaired the skin barrier. These findings suggest that TFH may have potential as an external treatment for AD.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Chemistry, Applied
Zhihua Geng, Jun Wang, Lichun Zhu, Xianlong Yu, Qian Zhang, Mengqing Li, Bin Hu, Xuhai Yang
Summary: This study used ultra-performance liquid chromatography and metabolomics to analyze the effects of hot air drying and infrared drying on flavonoid compounds and antioxidant capacity in sea buckthorn berries. The results showed that isorhamnetin and quercetin contents increased in response to drying, while (-)-epigallocatechin and (-)-gallocatechin contents decreased. The metabolism of flavonoid compounds mainly occurred in flavonoid biosynthesis and secondary metabolite biosynthesis pathways. This study elucidated the effect of drying on nutritional components of sea buckthorn berries and may guide the improvement of quality during food processing.
Article
Nutrition & Dietetics
Zheng Wang, Wenqian Wang, Changlong Zhu, Xiangdong Gao, Weihua Chu
Summary: The total flavonoids from sea buckthorn (Hippophae rhamnoides L.) have been found to possess antioxidative and neuroprotective activities, which can extend lifespan and potentially treat neurodegenerative diseases.
FRONTIERS IN NUTRITION
(2022)
Article
Veterinary Sciences
Rudolf Dupak, Jana Hrnkova, Nikoleta Simonova, Jan Kovac, Eva Ivanisova, Anna Kalafova, Monika Schneidgenova, Marta Soltesova Prnova, Jan Brindza, Katarina Tokarova, Marcela Capcarova
Summary: Sea buckthorn, known for its antioxidant effects, can effectively suppress hyperglycemia, reduce water intake, and lower sorbitol levels in the lens of the eyes in diabetic rats.
RESEARCH IN VETERINARY SCIENCE
(2022)
Review
Plant Sciences
Swati Pundir, Prakrati Garg, Ananya Dviwedi, Aaliya Ali, V. K. Kapoor, Deepak Kapoor, Saurabh Kulshrestha, Uma Ranjan Lal, Poonam Negi
Summary: Sea buckthorn is a flowering shrub native to cold temperate regions of Eurasia, primarily found in China. It is widely used in folk medicine for various skin-related issues, with phytochemical studies revealing the presence of a wide variety of bioactive compounds. Pharmacological studies have demonstrated its antibacterial, anti-sebum, antifungal, anti-psoriasis, anti-atopic dermatitis and wound healing activities, making it a valuable ingredient in cosmeceuticals.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Zili Guo, Jingya Cheng, Lei Zheng, Wenhao Xu, Yuanyuan Xie
Summary: The study explored a mechanochemical-assisted extraction method to extract flavonoids from sea buckthorn pomaces, resulting in a significant increase in extraction yield. The extracted flavonoids were found to have significant hepatoprotective activity, indicating a potential for the development of functional foods and comprehensive utilization of nature's resources.
Article
Multidisciplinary Sciences
Malgorzata Kubczak, Ainur B. Khassenova, Bartosz Skalski, Sylwia Michlewska, Marzena Wielanek, Maria Sklodowska, Araylim N. Aralbayeva, Zhanar S. Nabiyeva, Maira K. Murzakhmetova, Maria Zamaraeva, Maria Bryszewska, Maksim Ionov
Summary: Ethanol extracts from the leaves and twigs of Hippophae rhamnoides L. were found to be rich in bioactive compounds with potent antioxidant properties. These extracts showed low toxicity on human cells and may serve as an important source for the food, pharmaceutical and cosmetic industries.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Applied
Xingang Lyu, Xiao Wang, Qilei Wang, Xueying Ma, Suolian Chen, Jianbo Xiao
Summary: Encapsulation of sea buckthorn leaf extracts using electrohydrodynamic technology protected polyphenols and flavonoids, enhancing their bioaccessibility in the intestine and preserving their antioxidant activity and inhibition of metabolic syndrome-related enzymes. This innovative method may promote the use of sea buckthorn as a nutritional supplement and expand its commercial applications.
Article
Plant Sciences
Anita Zapalowska, Natalia Matlok, Milosz Zardzewialy, Tomasz Piechowiak, Maciej Balawejder
Summary: The ozone treatment significantly affected the quality of sea buckthorn berries, particularly in terms of volatile compounds and mechanical properties, extending the plant's storage life.
Article
Chemistry, Applied
Juan Wei, Sha Li, Tingting Su, Jinmei Zhao, Yumei Jiang, Yury A. Zubarev, Yang Bi
Summary: The phenolic ingredients of Hippophae tibetana and H. rhamnoides ssp. sinensis berries from the Qinghai-Tibet Plateau were identified. The results showed that both berries had high levels of total phenolic and flavonoid compounds, with Rha berries having higher contents. Additionally, Rha berries had higher levels of flavonols, while Tib berries had higher levels of flavanols. The phenolic extracts of both berries exhibited strong antioxidant properties, with Rha berries showing stronger effects due to their higher levels of phenolic and flavonoid profiles.
Article
Biochemistry & Molecular Biology
Wenna Zhou, Jian Ouyang, Na Hu, Honglun Wang
Summary: This study investigated the protective effect of three flavonoids against Dox-induced cardiomyocyte apoptosis. The results showed that these flavonoids could significantly alleviate Dox-induced cardiac injury and inhibit cardiomyocyte apoptosis by regulating mitochondrial structure and function, reducing intracellular ROS production, suppressing JNK and caspase-3 phosphorylation, increasing ATP content, and enhancing the expression of mitochondrial fusion proteins. These findings suggest that flavonoids from Hippophae rhamnoides Linn. can reduce Dox-induced H9c2 cell apoptosis through the 'JNK-Sab-Ros' signal pathway.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Applied
Chen Shen, Teng Wang, Feng Guo, Kunlai Sun, Bin Wang, Jie Wang, Zefeng Zhang, Xing Zhang, Yuqin Zhao, Yin Chen
Summary: A novel heteropolysaccharide fraction (SP0.1-1) was isolated from Sea buckthorn berries, with a specific composition and structure. Supplementing with SP0.1-1 extended fruit flies' lifespan, enhanced antioxidant enzyme activities, and reduced oxidative damage, showing potential for sea buckthorn polysaccharide products development.
CARBOHYDRATE POLYMERS
(2021)
Article
Biochemistry & Molecular Biology
Yu Han, Chen Yuan, Xiaowei Zhou, Yingjie Han, Yanhao He, Jian Ouyang, Wenna Zhou, Zhenhua Wang, Honglun Wang, Gang Li
Summary: OA, AA, and MA exhibit significant anti-inflammatory effects in vitro, with OA and AA exerting their effects through MAPKs, NF-kappa B, and Nrf2 signaling pathways.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Forestry
Guoyun Zhang, Songfeng Diao, Yating Song, Caiyun He, Jianguo Zhang
Summary: This study observed the distribution patterns of DNA 6mA methylation in the sea buckthorn genome and found that it plays an important role in the fruit ripening process.