Neurogenin 3 Expressing Cells in the Human Exocrine Pancreas Have the Capacity for Endocrine Cell Fate

Pancreatic β Cell Dedifferentiation in Diabetes and Redifferentiation following Insulin Therapy

(2014) Zhiyu Wang et al.   Cell Metabolism

Loss of Fbw7 Reprograms Adult Pancreatic Ductal Cells into α, δ, and β Cells

(2014) Rocio Sancho et al.   Cell Stem Cell

CD133 might be a pan marker of epithelial cells with dedifferentiation capacity

(2014) D. Corbeil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch-mediated post-translational control of Ngn3 protein stability regulates pancreatic patterning and cell fate commitment

(2013) Xiaoling Qu et al.   DEVELOPMENTAL BIOLOGY

Gene Regulatory Networks Governing Pancreas Development

(2013) H. Efsun Arda et al.   DEVELOPMENTAL CELL

Development of the Human Pancreas From Foregut to Endocrine Commitment

(2013) R. E. Jennings et al.   DIABETES

Neurogenin3 Activation Is Not Sufficient to Direct Duct-to-Beta Cell Transdifferentiation in the Adult Pancreas

(2013) Xiangwei Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

No evidence for β cell neogenesis in murine adult pancreas

(2013) Xiangwei Xiao et al.   JOURNAL OF CLINICAL INVESTIGATION

Activin A, exendin-4, and glucose stimulate differentiation of human pancreatic ductal cells

(2013) Hyo-Sup Kim et al.   JOURNAL OF ENDOCRINOLOGY

Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice

(2013) Luc Baeyens et al.   NATURE BIOTECHNOLOGY

Neurogenin 3+ cells contribute to β-cell neogenesis and proliferation in injured adult mouse pancreas

(2013) M Van de Casteele et al.   Cell Death & Disease

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

(2012) Chutima Talchai et al.   CELL

Notch-mediated patterning and cell fate allocation of pancreatic progenitor cells

(2012) S. Afelik et al.   DEVELOPMENT

Local In Vivo GSK3β Knockdown Promotes Pancreatic β Cell and Acinar Cell Regeneration in 90% Pancreatectomized Rat

(2012) Florence Figeac et al.   MOLECULAR THERAPY

Differential analysis of gene regulation at transcript resolution with RNA-seq

(2012) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Analysis of Beta-Cell Gene Expression Reveals Inflammatory Signaling and Evidence of Dedifferentiation following Human Islet Isolation and Culture

(2012) Sarita Negi et al.   PLoS One

Plasticity of Adult Human Pancreatic Duct Cells by Neurogenin3-Mediated Reprogramming

(2012) Nathalie Swales et al.   PLoS One

Lineage Tracing Evidence for Transdifferentiation of Acinar to Duct Cells and Plasticity of Human Pancreas

(2011) Isabelle Houbracken et al.   GASTROENTEROLOGY

CD133 ProteinN-Glycosylation Processing Contributes to Cell Surface Recognition of the Primitive Cell Marker AC133 Epitope

(2011) Anthony B. Mak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pancreatic ductal cells in development, regeneration, and neoplasia

(2011) Maximilian Reichert et al.   JOURNAL OF CLINICAL INVESTIGATION

Chemical screen identifies FDA-approved drugs and target pathways that induce precocious pancreatic endocrine differentiation

(2011) M. Rovira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pancreatic Mesenchyme Regulates Epithelial Organogenesis throughout Development

(2011) Limor Landsman et al.   PLOS BIOLOGY

Nkx6 Transcription Factors and Ptf1a Function as Antagonistic Lineage Determinants in Multipotent Pancreatic Progenitors

(2010) Ashleigh E. Schaffer et al.   DEVELOPMENTAL CELL

MafA and MafB Regulate Genes Critical to  -Cells in a Unique Temporal Manner

(2010) I. Artner et al.   DIABETES

Significant Human β-Cell Turnover Is Limited to the First Three Decades of Life as Determined byin VivoThymidine Analog Incorporation and Radiocarbon Dating

(2010) S. Perl et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

(2010) Fabrizio Thorel et al.   NATURE

The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation

(2009) M. Cnop et al.   DIABETOLOGIA

Cooperative Transcriptional Regulation of the Essential Pancreatic Islet GeneNeuroD1(Beta2) by Nkx2.2 and Neurogenin 3

(2009) Keith R. Anderson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of parenchymal injury and signaling pathways in ectatic ducts of chronic pancreatitis: implications for pancreatic carcinogenesis

(2009) Umesh K Bhanot et al.   LABORATORY INVESTIGATION

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function

(2009) S. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas

(2009) M. Rovira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β Cells Can Be Generated from Endogenous Progenitors in Injured Adult Mouse Pancreas

(2008) Xiaobo Xu et al.   CELL

Transcription factor expression in the developing human fetal endocrine pancreas

(2008) B. M. Lyttle et al.   DIABETOLOGIA

In vivo reprogramming of adult pancreatic exocrine cells to β-cells

(2008) Qiao Zhou et al.   NATURE

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

(2008) Eleftheria Zeggini et al.   NATURE GENETICS

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Differentiation of CD133-Positive Pancreatic Cells Into Insulin-Producing Islet-Like Cell Clusters

(2008) T. Koblas et al.   TRANSPLANTATION PROCEEDINGS

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

(2003) H. F. Dovey et al.   JOURNAL OF NEUROCHEMISTRY