Efficient Generation of Myostatin Knock-Out Sheep Using CRISPR/Cas9 Technology and Microinjection into Zygotes

Single-step generation of rabbits carrying a targeted allele of the tyrosinase gene using CRISPR/Cas9

(2015) Arata HONDA et al.   EXPERIMENTAL ANIMALS

Molecular scissors and their application in genetically modified farm animals

(2015) Bjoern Petersen et al.   TRANSGENIC RESEARCH

Use of the CRISPR/Cas9 System to Produce Genetically Engineered Pigs from In Vitro-Derived Oocytes and Embryos1

(2014) Kristin M. Whitworth et al.   BIOLOGY OF REPRODUCTION

Highly efficient targeted chromosome deletions using CRISPR/Cas9

(2014) Zuyong He et al.   BIOTECHNOLOGY AND BIOENGINEERING

Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos

(2014) Yuyu Niu et al.   CELL

One-step generation of knockout pigs by zygote injection of CRISPR/Cas system

(2014) Tang Hai et al.   CELL RESEARCH

Generation of CRISPR/Cas9-mediated gene-targeted pigs via somatic cell nuclear transfer

(2014) Xiaoqing Zhou et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases

(2014) Séverine Remy et al.   GENOME RESEARCH

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

(2014) Yanfang Fu et al.   NATURE BIOTECHNOLOGY

Efficient Gene Knockout in Goats Using CRISPR/Cas9 System

(2014) Wei Ni et al.   PLoS One

Characterization of Dystrophin Deficient Rats: A New Model for Duchenne Muscular Dystrophy

(2014) Thibaut Larcher et al.   PLoS One

Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA

(2014) C. Long et al.   SCIENCE

Embryo development, fetal growth and postnatal phenotype of eGFP lambs generated by lentiviral transgenesis

(2014) M. Crispo et al.   TRANSGENIC RESEARCH

Genome edited sheep and cattle

(2014) Chris Proudfoot et al.   TRANSGENIC RESEARCH

Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

(2013) F. Ann Ran et al.   CELL

Targeted disruption of the sheep MSTN gene by engineered zinc-finger nucleases

(2013) Cunfang Zhang et al.   MOLECULAR BIOLOGY REPORTS

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

(2013) Yanfang Fu et al.   NATURE BIOTECHNOLOGY

Efficient nonmeiotic allele introgression in livestock using custom endonucleases

(2013) W. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Generation of Rag1-knockout immunodeficient rats and mice using engineered meganucleases

(2012) Séverine Ménoret et al.   FASEB JOURNAL

Lack of association between allelic status and myostatin content in lambs with the myostatin g+6723G > A allele1

(2012) F. E. M. Haynes et al.   JOURNAL OF ANIMAL SCIENCE

Double Muscling in Cattle: Genes, Husbandry, Carcasses and Meat

(2012) Leo O. Fiems   Animals

Polymorphisms of myostatin gene (MSTN) in four goat breeds and their effects on Boer goat growth performance

(2011) Chunyan Zhang et al.   MOLECULAR BIOLOGY REPORTS

TALEs of genome targeting

(2011) Jens Boch   NATURE BIOTECHNOLOGY

Advances in farm animal transgenesis

(2011) Wilfried A. Kues et al.   PREVENTIVE VETERINARY MEDICINE

CRISPR/Cas, the Immune System of Bacteria and Archaea

(2010) P. Horvath et al.   SCIENCE

Myostatin Inhibition Enhances the Effects of Exercise on Performance and Metabolic Outcomes in Aged Mice

(2009) N. K. LeBrasseur et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The effects of a mutation in the myostatin gene on meat and carcass quality

(2009) P. Wiener et al.   MEAT SCIENCE

Zinc-finger nucleases: a powerful tool for genetic engineering of animals

(2009) Séverine Rémy et al.   TRANSGENIC RESEARCH

Epigenetic reprogramming in embryonic and foetal development upon somatic cell nuclear transfer cloning

(2008) Heiner Niemann et al.   REPRODUCTION

Production of Transgenic Farm Animals by Viral Vector-Mediated Gene Transfer

(2008) CBA Whitelaw et al.   REPRODUCTION IN DOMESTIC ANIMALS

Aberrant DNA methylation imprints in aborted bovine clones

(2007) Jing-He Liu et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT