Andrographolide Analogue Induces Apoptosis and Autophagy Mediated Cell Death in U937 Cells by Inhibition of PI3K/Akt/mTOR Pathway

Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells

(2014) Ugur Akar et al.   Autophagy

Nelfinavir, a new anti-cancer drug with pleiotropic effects and many paths to autophagy

(2014) Joell J. Gills et al.   Autophagy

Novel monofunctional platinum (II) complex Mono-Pt induces apoptosis-independent autophagic cell death in human ovarian carcinoma cells, distinct from cisplatin

(2013) Wen-Jie Guo et al.   Autophagy

Apoptotic and Autophagic Effects of Sesbania grandiflora Flowers in Human Leukemic Cells

(2013) Rajneeta Roy et al.   PLoS One

Andrographolide sensitizes cisplatin-induced apoptosis via suppression of autophagosome-lysosome fusion in human cancer cells

(2012) Jing Zhou et al.   Autophagy

Inhibiting autophagy potentiates the anticancer activity of IFN1@/IFNα in chronic myeloid leukemia cells

(2012) Shan Zhu et al.   Autophagy

IFNB1/interferon-β-induced autophagy in MCF-7 breast cancer cells counteracts its proapoptotic function

(2012) Malene Ambjørn et al.   Autophagy

Andrographolide induces autophagic cell death in human liver cancer cells through cyclophilin D-mediated mitochondrial permeability transition pore

(2012) Wei Chen et al.   CARCINOGENESIS

Acute promyelocytic leukemia, arsenic, and PML bodies

(2012) Hugues de Thé et al.   JOURNAL OF CELL BIOLOGY

Malabaricone-A Induces A Redox Imbalance That Mediates Apoptosis in U937 Cell Line

(2012) Alak Manna et al.   PLoS One

Minocycline inhibits the growth of glioma by inducing autophagy

(2011) Wei-Ting Liu et al.   Autophagy

Quercetin induces protective autophagy in gastric cancer cells: Involvement of Akt-mTOR- and hypoxia-induced factor 1α-mediated signaling

(2011) Kui Wang et al.   Autophagy

Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition

(2011) Shinji Saiki et al.   Autophagy

Apoptotic and autophagic responses to photodynamic therapy in 1c1c7 murine hepatoma cells

(2011) Michelle Andrzejak et al.   Autophagy

Defective Hypothalamic Autophagy Directs the Central Pathogenesis of Obesity via the IκB Kinase β (IKKβ)/NF-κB Pathway

(2011) Qingyuan Meng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy

(2011) L S Steelman et al.   LEUKEMIA

Bnip3-mediated mitochondrial autophagy is independent of the mitochondrial permeability transition pore

(2010) Melissa N. Quinsay et al.   Autophagy

ROS-mediated mechanisms of autophagy stimulation and their relevance in cancer therapy

(2010) Michael Dewaele et al.   Autophagy

Combination treatment with arsenic trioxide and irradiation enhances cell-killing effects in human fibrosarcoma cells in vitro and in vivo through induction of both autophagy and apoptosis

(2010) Hui-Wen Chiu et al.   Autophagy

Autophagy potentiates the anti-cancer effects of the histone deacetylase inhibitors in hepatocellular carcinoma

(2010) Yuan-Ling Liu et al.   Autophagy

Areca nut extract induced oxidative stress and upregulated hypoxia inducing factor leading to autophagy in oral cancer cells

(2010) Hsuan-Hsuan Lu et al.   Autophagy

Synthesis, cytotoxicity, and structure–activity relationship (SAR) studies of andrographolide analogues as anti-cancer agent

(2010) Bimolendu Das et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells

(2010) Y. Suh et al.   CARCINOGENESIS

Discovery and Development of Natural Product-Derived Chemotherapeutic Agents Based on a Medicinal Chemistry Approach⊥†

(2010) Kuo-Hsiung Lee   JOURNAL OF NATURAL PRODUCTS

Observations on the synaptic ribbon morphology in retinas of two human subjects at autopsy

(2009) Tapas C. Nag et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Platonin induces autophagy-associated cell death in human leukemia cells

(2009) Yu-Jen Chen et al.   Autophagy

Combination treatment with arsenic trioxide and irradiation enhances autophagic effects in U118-MG cells through increased mitotic arrest and regulation of PI3K/Akt and ERK1/2 signaling pathways

(2009) Hui-Wen Chiu et al.   Autophagy

Cathepsin L mediates resveratrol-induced autophagy and apoptotic cell death in cervical cancer cells

(2009) Keng-Fu Hsu et al.   Autophagy

Apoptotic effects of mahanine on human leukemic cells are mediated through crosstalk between Apo-1/Fas signaling and the Bid protein and via mitochondrial pathways

(2009) Kaushik Bhattacharya et al.   BIOCHEMICAL PHARMACOLOGY

Life and death partners: apoptosis, autophagy and the cross-talk between them

(2009) A Eisenberg-Lerner et al.   CELL DEATH AND DIFFERENTIATION

Flow cytometric determination of intracellular non-protein thiols in Leishmania promastigotes using 5-chloromethyl fluorescein diacetate

(2009) Avijit Sarkar et al.   EXPERIMENTAL PARASITOLOGY

Regulation of Autophagy by Reactive Oxygen Species (ROS): Implications for Cancer Progression and Treatment

(2008) Meghan B. Azad et al.   ANTIOXIDANTS & REDOX SIGNALING

Withaferin A induces apoptosis by activating p38 mitogen-activated protein kinase signaling cascade in leukemic cells of lymphoid and myeloid origin through mitochondrial death cascade

(2008) Chandan Mandal et al.   APOPTOSIS

Targeting the PI3K/Akt/mTOR pathway: Effective combinations and clinical considerations

(2008) J LOPICCOLO et al.   DRUG RESISTANCE UPDATES

Caspases in apoptosis and beyond

(2008) J Li et al.   ONCOGENE