Article
Chemistry, Analytical
Nurzad Zakirov, Shaodi Zhu, Aurelien Bruyant, Gilles Lerondel, Renaud Bachelot, Shuwen Zeng
Summary: In this study, structures based on copper nanosubstrate with graphene and two-dimensional transition metal dichalcogenides (TMDC) were designed to achieve an ultrasensitive surface plasmon resonance biosensor. Theoretical calculations showed an enhanced sensitivity with a detection limit of 10^(-9) refractive index unit (RIU) by optimizing the parameters of the SPR sensing substrate.
Article
Chemistry, Physical
Ahmad Aziz Darweesh, Desalegn Tadesse Debu, Stephen Joseph Bauman, Joseph Bruce Herzog
Summary: In this study, we designed and simulated asymmetric bimetallic nanodimers and found that changing particle size significantly affects the optical properties of the nanostructures. We observed different plasmonic resonant modes and spectral changes in the heterodimers, and the peak values of the far-field enhancement spectra showed red-shifts.
Review
Biology
Mohga E. Hamza, Muhammad A. Othman, Mohamed A. Swillam
Summary: Plasmonic biosensors have great potential for wide applications due to their high specificity and sensitivity. Choosing the appropriate materials, structures, and functionality is crucial for developing plasmonic biosensors for specific applications. This review discusses the working mechanism of plasmonic biosensors, methods of controlling efficiency, and their different designs in various applications.
Review
Chemistry, Analytical
Yanting Liu, Xuming Zhang
Summary: This review summarizes the recent advances in plasmonic biosensors integrated with microfluidic chips for biomedical detection applications, showcasing enhanced performance through continuous advancements in plasmon resonance techniques. Microfluidic integration enables multiplexing opportunities for simultaneous detection of multiple analytes with high sensitivity, label-free, and real-time performance, benefiting a wide range of biomedical studies, chemical analyses, and point-of-care diagnostics.
Article
Chemistry, Analytical
Andreas Dahlin
Summary: The research field of nanoplasmonic sensors, particularly focused on affinity-based detection using refractive index changes, is scrutinized in this review. Nanostructured plasmonic sensors offer unique advantages compared to traditional surface plasmon resonance techniques, but their usefulness is limited to specific situations. The main challenges in the field are related to limited receptor affinity and nonspecific binding.
ANNUAL REVIEW OF ANALYTICAL CHEMISTRY, VOL 14, 2021
(2021)
Article
Chemistry, Analytical
Vivek Semwal, Oliver Rishoj Jensen, Ole Bang, Jakob Janting
Summary: This paper presents numerical and experimental results on the effects of spherical gold nanoparticles (AuNPs) size on Localized Surface Plasmon Resonance (LSPR) refractive index (RI) sensitivity, Figure of Merit (FoM), and penetration depth (dp). The study also investigates the influence of AuNP dimer interparticle distance (ds) on these parameters. The results show that a diameter of 60 nm AuNPs provides the best FoM. Furthermore, the interparticle distance between d = 20 nm and 60 nm AuNPs significantly affects the RI sensitivity. The importance of penetration depth information for biosensing using aptamers is discussed in relation to aptamer size.
Review
Chemistry, Multidisciplinary
Devi Taufiq Nurrohman, Nan-Fu Chiu
Summary: The surface plasmon resonance (SPR) biosensor is a powerful analytical tool for investigating biomolecular interactions, and graphene has been widely studied as a material to increase the sensor's sensitivity through various excitation methods. Current development of graphene-based SPR biosensor includes discussion on graphene properties, its application in biosensors, simulation, and experimental results of different excitation methods. Additionally, a review on graphene-based Surface-Enhanced Raman Scattering (SERS) biosensor expands the discussion on SPR biosensors, providing an overview of future material development in biosensors.
Article
Chemistry, Multidisciplinary
Jean-Francois Bryche, Marlo Vega, Agnes Tempez, Thibault Brule, Thomas Carlier, Julien Moreau, Marc Chaigneau, Paul G. Charette, Michael Canva
Summary: This work demonstrates the enhancement in plasmonic sensing efficacy by spatially-localized functionalization on nanostructured surfaces, where probe molecules are concentrated in areas of high field concentration. SERS measurements on nanostructured surfaces with homogeneous and spatially-localized functionalization with thiophenol show that the Raman signal mainly originates from high field concentration areas. TERS measurements with 10 nm spatial resolution confirm the predicted field distribution profiles.
Article
Chemistry, Analytical
Prerit Mathur, Anna Fomitcheva Khartchenko, Stavros Stavrakis, Govind V. Kaigala, Andrew J. deMello
Summary: We developed a method for monitoring localized antigen-antibody binding on cell and tissue sections using fluorescence lifetime imaging. By measuring the difference in fluorescence decay times of tagged antibodies in free solution and in the bound state, we can track the binding fraction over time and determine the binding kinetics. This method allows us to measure binding constants and observe biomarker expression effects on kinetics.
ANALYTICAL CHEMISTRY
(2022)
Article
Biophysics
Tianping Xu, Zhaoxin Geng
Summary: Due to the lower sensitivity of LSPR biosensors compared to other sensors, researchers have explored various methods to improve performance, including structural, material, and interface modifications. These efforts are expected to expand the applications of LSPR biosensing technology.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Multidisciplinary
Aline dos Santos Almeida, Dario A. Bahamon, Nuno M. R. Peres, Christiano J. S. de Matos
Summary: The use of graphene in surface plasmon resonance sensors has advantages such as protecting the film and increasing sensitivity. However, the role of single and few layers of graphene in sensitivity enhancement was critically examined, and it was found that only the isotropic layer model provides significant sensitivity increases.
Article
Chemistry, Multidisciplinary
Xi Yang, Dong Su, Xie Yu, Pei Zeng, Huageng Liang, Guangzu Zhang, Boxiang Song, Shenglin Jiang
Summary: The controllable nanogap structures enable strong and adjustable localized surface plasmon resonance (LSPR). A novel hierarchical plasmonic nanostructure (HPN) is created using colloidal lithography with a rotating coordinate system. The HPN increases the density of hot spots and enhances LSPR tunability and field enhancement. The hot spot engineering strategy of HPNs is demonstrated in surface-enhanced Raman spectroscopy (SERS) applications and allows single-molecule level detection and long-range mapping, providing a platform and guidance for various LSPR applications.
Article
Engineering, Electrical & Electronic
Ajay Kumar Agrawal, Akanksha Ninawe, Anuj Dhawan
Summary: This paper reports a significantly improved sensing response of a plasmonic sensor based on a nanopillar array separated from a thin film, operated using the Kretschmann configuration. The sensor shows high sensitivity and figure of merit for both localized and bulk sensing responses. It can be easily fabricated and has great potential for biosensing applications.
IEEE SENSORS JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Chun-Yuan Wang, Yungang Sang, Xinyue Yang, Soniya S. Raja, Chang-Wei Cheng, Haozhi Li, Yufeng Ding, Shuoyan Sun, Hyeyoung Ahn, Chih-Kang Shih, Shangjr Gwo, Jinwei Shi
Summary: This study demonstrates a strong coupling system achieved by coupling localized surface plasmon modes. Under specific conditions, a root N scaling of Rabi splitting energy is observed, along with a confirmed giant Rabi splitting in the visible spectral range. Additionally, the coupling strength reaches the ultrastrong coupling regime in some cases, representing about 10% of the mode energy.
Article
Chemistry, Analytical
Maryam Sharifi, Balal Khalilzadeh, Farzaneh Bayat, Ibrahim Isildak, Habib Tajalli
Summary: Due to the poor prognosis of pancreatic cancer, early detection tests are essential. This study developed a biosensor based on localized surface plasmon resonance (LSPR) for early-stage detection of CA-19-9, a biomarker for pancreatic cancer. The biosensor showed high sensitivity and accuracy in detecting CA-19-9.
MICROCHEMICAL JOURNAL
(2023)
Editorial Material
Optics
Gregory Barbillon
Article
Physics, Applied
Andrey K. Sarychev, Andrey Ivanov, Andrey N. Lagarkov, Ilya Ryzhikov, Konstantin Afanasev, Igor Bykov, Gregory Barbillon, Nikita Bakholdin, Mikhail Mikhailov, Alexander Smyk, Alexander Shurygin, Alexander Shalygin
Summary: This study presents the design and fabrication of metal-dielectric metasurfaces, as well as their application in the excitation of plasmons and surface-enhanced Raman scattering. By utilizing the periodic arrangement of metal nanogratings on a dielectric substrate, an open plasmon resonator is formed, leading to the enhancement of the local electromagnetic field at optical frequencies.
PHYSICAL REVIEW APPLIED
(2022)
Article
Physics, Applied
Jeremy Bonhomme, Mourad Oudich, Mohamed Lamine Faycal Bellaredj, Jean-Francois Bryche, Pedro Alberto Segura Chavez, Denis Beyssen, Paul G. Charette, Frederic Sarry
Summary: The interaction of Love waves with micropillars on the guiding layer surface produces sharp attenuation dips in the transmission spectrum, utilizing the local resonances of the micropillars. These dips are associated with the excitations of flexural and torsional resonance modes of the pillars, enabling higher detection sensitivity for temperature variations and mass loading.
PHYSICAL REVIEW APPLIED
(2022)
Article
Optics
Gregory Barbillon
Summary: This study presents a research on the sensing of chemical molecules using Au nanoparticles coated ZnO film by employing the photo-induced enhanced Raman scattering (PIERS) coupled to the surface-enhanced Raman scattering (SERS). The aim of coupling the PIERS to classical SERS is to achieve high sensitivity of detection. The detection of thiophenol showed a limit concentration of 100 pM, an adsorption capacity (K-Ads) of 3.2 x 10(6) M-1 and an analytical enhancement factor of 1.9 x 10(10).
Article
Biophysics
Zhor Khadir, Victor Schmidt, Kevin Chabot, Jean-Francois Bryche, Ulrike Froehlich, Julien Moreau, Michael Canva, Paul Charette, Michel Grandbois
Summary: This study utilizes surface micropatterning techniques to control the adhesion of endothelial cells and establish a well-controlled cell layer phenotype on SPR sensor surfaces. The formation of cell-cell junctions can be controlled by tuning the inter-cellular spacing. The functionality of the proposed model has been confirmed through fluorescence microscopy and SPRI.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Chemistry, Multidisciplinary
Jean-Francois Bryche, Marlo Vega, Agnes Tempez, Thibault Brule, Thomas Carlier, Julien Moreau, Marc Chaigneau, Paul G. Charette, Michael Canva
Summary: This work demonstrates the enhancement in plasmonic sensing efficacy by spatially-localized functionalization on nanostructured surfaces, where probe molecules are concentrated in areas of high field concentration. SERS measurements on nanostructured surfaces with homogeneous and spatially-localized functionalization with thiophenol show that the Raman signal mainly originates from high field concentration areas. TERS measurements with 10 nm spatial resolution confirm the predicted field distribution profiles.
Article
Engineering, Electrical & Electronic
P. Girault, L. Oyhenart, T. Rouanet, S. Joly, G. Beaudin, M. Canva, L. Bechou, P. G. Charette
Summary: This work presents a detailed modeling-based analysis of integrated micro-ring resonators used for absorption spectroscopy. Typically, sensors based on micro-ring resonators detect changes in the real part of the refractive index of the sensing medium at critical coupling. However, in absorption spectroscopy, micro-ring resonators are used to measure changes in the imaginary part of the index and are most sensitive away from critical coupling, with separate maxima in the under- and over-coupled regimes. The analysis in this work focuses on the under-coupled regime, exploring the relationships between sensitivity, mode confinement, and losses.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2023)
Article
Nanoscience & Nanotechnology
Jean-Francois Bryche, Marlo Vega, Julien Moreau, Paul-Ludovic Karsenti, Paul Bresson, Mondher Besbes, Philippe Gogol, Denis Morris, Paul G. Charette, Michael Canva
Summary: Thermoplasmonics has gained increasing attention for generating nanoscale heat sources using photothermal effects in plasmonic nanoparticles. By exciting gold nanoparticles with ultrashort light pulses, high-speed light management and nanoscale heat-sensitive chemical reaction control can be achieved. This study investigates the non-uniform thermal energy distribution in cross-shaped nanostructures using femtosecond transient spectroscopy and a thermooptical numerical model. The results show that the polarization of the excitation light can control heat distribution in the nanostructures, and nonthermal electron ballistic displacement is crucial in fast transient heat dynamics models.
Article
Chemistry, Analytical
M. Vega, J. -F. Bryche, P. -L. Karsenti, P. Gogol, M. Canva, P. G. Charette
Summary: This paper proposes a 2D method for removing coherent artifacts from femtosecond time-resolved spectroscopy data, which is simple, intuitive, and light on computation resources. The effectiveness of the method is demonstrated with experimental data, and it is expected to be applicable to other types of time and wavelength-resolved spectroscopy data.
ANALYTICA CHIMICA ACTA
(2023)
Review
Physics, Applied
Alemayehu Nana Koya, Marco Romanelli, Joel Kuttruff, Nils Henriksson, Andrei Stefancu, Gustavo Grinblat, Aitor De Andres, Fritz Schnur, Mirko Vanzan, Margherita Marsili, Mahfujur Rahaman, Alba Viejo Rodriguez, Tlek Tapani, Haifeng Lin, Bereket Dalga Dana, Jingquan Lin, Gregory Barbillon, Remo Proietti Zaccaria, Daniele Brida, Deep Jariwala, Laszlo Veisz, Emiliano Cortes, Stefano Corni, Denis Garoli, Nicolo Maccaferri
Summary: In the past twenty years, significant progress has been made in understanding light-driven phenomena in nanoscale systems, while exploring the temporal dynamics of excited states remains a challenge. Ultrafast plasmonics, which focuses on tailoring and controlling optical and electronic processes at the nanoscale, offers great potential for applications such as optical switching and photochemical reactions. This review provides an overview of the field, discussing methodologies for monitoring and controlling nanoscale phenomena with plasmons, and highlighting recent advances in plasmon-driven chemistry and multifunctional plasmonics.
APPLIED PHYSICS REVIEWS
(2023)
Article
Chemistry, Physical
Gregory Barbillon
Summary: This study investigates the Fermi level shifts of gold nanospheres on zinc oxide (ZnO) film upon UV irradiation. The shifts are obtained by recording the extinction spectra of gold nanospheres and are attributed to the additional electrons stored in the nanospheres from ZnO film. The blueshift of plasmon resonance of the Au nanospheres indicates the transfer of electrons from ZnO film to Au nanospheres upon UV irradiation. The Fermi level shifts vary with UV irradiation time and can be estimated by a model based on the electronic structure of a semiconductor.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Article
Chemistry, Multidisciplinary
Andrey K. Sarychev, Gregory Barbillon, Andrey Ivanov
Summary: This study presents generic, analytical equations for the localized plasmons in a narrow gap between a metal/dielectric cylinder and a metal surface. The electric field distribution in the nanogap is obtained using the quasi-static approximation. The maximum electric field is achieved when the incident light is in resonance with the plasmon mode in the gap, and can be significantly enhanced. The analytical model results are in good agreement with a known theoretical model and experimental results of surface-enhanced Raman scattering (SERS). The narrow gap resonator appears to be a powerful and flexible tool for various spectroscopies such as SERS and infrared absorption.
APPLIED SCIENCES-BASEL
(2023)
