Article
Psychology, Clinical
Chittaranjan Andrade
Summary: Sevoflurane may shorten EEG seizure duration in ECT anesthesia compared to IV anesthetics, but has different effects on heart rate and mean arterial pressure and no significant difference in adverse events. However, its use requires additional anesthesia instruments and increases the complexity of the ECT procedure.
JOURNAL OF CLINICAL PSYCHIATRY
(2021)
Article
Environmental Sciences
Sergio Parra, Manuel Geronimo-Pardo, Maria Luisa Gonzalez-Moral
Summary: This study assessed the hemolytic potential of three anesthetics, isoflurane, desflurane, and sevoflurane, at two different concentrations in vitro. The results showed that sevoflurane had negligible hemolytic potential compared to isoflurane and desflurane. However, the use of preloaded sevoflurane syringes may still be problematic due to the increased risk of inadvertent intravenous administration.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2022)
Article
Critical Care Medicine
Adrian-Iustin Georgevici, Theodoros Kyprianou, Jennifer Herzog-Niescery, Livia Procopiuc, Sivakkanan Loganathan, Thomas Peter Weber, Martin Bellgardt
Summary: This study aimed to compare the effects of different volatile anesthetics on sedation depth in ICU patients. Results show that despite constant MAC, the EEG-derived Narcotrend-Index may drift downward over sedation time. Therefore, patients may require frequent clinical assessments or continuous EEG monitoring.
Article
Chemistry, Physical
Mads P. Sulbaek Andersen, Aleksandra Volkova, Sofie A. Hass, Jonathan W. Lengkong, Dvien Hovanessian, Theis Solling, Timothy J. Wallington, Ole J. Nielsen
Summary: This study investigates the kinetics and mechanisms of the oxidation of (Z)- and (E)-1,2-dichloroethene under atmospheric conditions. Smog chambers interfaced with in situ FT-IR detection were used to measure the rate constants of different reactions and study the formation of products. The results show that chlorine atom elimination and photochemical ozone creation potential play important roles in the atmospheric chemistry of these compounds.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Article
Multidisciplinary Sciences
Jeayoun Kim, Doyeon Kim, Inho Kim, Ji Seon Jeong
Summary: This study compared the changes in BIS and PSI values caused by the use of sugammadex for neuromuscular blockade reversal. The results showed that there were no significant differences in the changes of BIS and PSI values compared to baseline after sugammadex administration. However, the maximum BIS and PSI values were significantly higher than baseline. Weak positive correlations were found between BIS and BIS-EMG, as well as PSI and PSI-EMG, indicating that both BIS and PSI were affected by EMG artifacts.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Physical
Tomasz Gierczak, Francois Bernard, Dimitrios K. Papanastasiou, James B. Burkholder
Summary: c-C5HF7 and c-C5F8 are potent greenhouse gases used in Si etching, with atmospheric lifetimes estimated to be 252 and 236 days, and global warming potential values of 46.7 and 46.2, respectively. Their reaction with the OH radical results in specific end-products, with a C5-dicarbonyl end-product observed for both compounds. The rate coefficients for their reactions with the OH radical were found to be pressure-independent over a range of conditions.
JOURNAL OF PHYSICAL CHEMISTRY A
(2021)
Article
Chemistry, Physical
Sergio Blazquez, Sara Espinosa, Maria Antinolo, Jose Albaladejo, Elena Jimenez
Summary: Hydrofluoroethers (HFEs) have been proposed as third-generation replacements for perfluorocarbons (PFCs) and hydrofluorocarbons (HFCs) due to their environmental benefits. This study focuses on the temperature and pressure dependencies of the reaction rate coefficients of three HFEs. The results show that there is no pressure dependence observed within the range studied, and the reaction rates can be described by mathematical models. Additionally, the impact of these HFEs on climate change is found to be negligible.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Article
Chemistry, Physical
Abolfazl Shiroudi, Jacek Czub, Mohammednoor Altarawneh
Summary: The degradation of Trichlorofluoroethene (TCFE) initiated by OH center dot radicals was studied using theoretical models. The results showed that OH-addition is the dominant pathway, leading to the formation of C(OH)Cl-2-(CClF)-C-center dot and (CCl2)-C-center dot-C(OH)ClF species. Pathway 1 exhibited greater exothermicity and exergonicity compared to pathway 2. The atmospheric lifetime of TCFE was estimated to be 8.49 days, with low ozone depletion potential and high photochemical ozone creation potential.
Article
Anesthesiology
Xiang Bingbing, Jiao Shulan, Zhang Yulong, Wang Lu, Yao Yuting, Yuan Feng, Chen Rui, Zhou Qijun
Summary: Studies have shown that both desflurane and sevoflurane have a dose-dependent inhibitory effect on SEPs and MEPs during neurosurgery, with desflurane appearing to have a stronger inhibitory effect at the same MAC concentration compared to sevoflurane.
BMC ANESTHESIOLOGY
(2021)
Article
Environmental Sciences
Maria Asensio, Maria Antinolo, Sergio Blazquez, Jose Albaladejo, Elena Jimenez
Summary: This study reports the rate coefficients for the gas-phase reactions of 2MB with OH and Cl, as well as the photolysis rate coefficient in the ultraviolet solar actinic region. Experimental identification and quantification of the reaction products and photodissociation products were performed, and the formation and size distribution of secondary organic aerosols were monitored. The study also discusses the importance of the first step in the daytime atmospheric degradation of 2MB and its impact on marine atmospheres.
ATMOSPHERIC CHEMISTRY AND PHYSICS
(2022)
Article
Environmental Sciences
Mads Peter Sulbaek Andersen, Ole John Nielsen, Jodi D. Sherman
Summary: There is growing concern in the healthcare community about the impact of care delivery on environmental degradation, prompting research on reducing pollution from clinical practice. Inhaled anaesthetics are of particular interest due to their potential as greenhouse gases and the possibility of substituting them with lower-emission alternatives. This review examines the current literature on the environmental impact and estimation of climate forcing of common inhaled anaesthetic drugs.
LANCET PLANETARY HEALTH
(2023)
Article
Anesthesiology
Coralie Chambrin, Sander de Souza, Claire Gariel, Dominique Chassard, Lionel Bouvet
Summary: The implementation of sustainable anesthesia groups and an information campaign in Lyon, France, was associated with a significant reduction in the carbon footprint related to inhaled halogenated anesthetics.
ANESTHESIA AND ANALGESIA
(2023)
Article
Chemistry, Physical
Xiaoxiao Lin, Rongrong Hu, Ziji Ma, Hao Yue, Zuoying Wen, Cuihong Zhang, Christa Fittschen, Weijun Zhang, Xiaofeng Tang
Summary: The Cl-initiated oxidation of methacrolein under NOx-free conditions was investigated using experimental and theoretical methods. The photoionization mass spectra confirmed the presence of key species involved in the reaction. The reaction mechanism and kinetics were studied to provide insights into the oxidation process.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Review
Anesthesiology
Shane Varughese, Raza Ahmed
Summary: Inhaled anesthetics such as N2O and sevoflurane are potent greenhouse gases and ozone-depleting agents, posing risks to personnel through occupational exposure. Specific measures to reduce occupational exposure and environmental impact, such as efficient ventilation systems and regular monitoring of waste gas concentrations, should be implemented to mitigate these risks.
ANESTHESIA AND ANALGESIA
(2021)
Article
Anesthesiology
Linda L. Liu, Merlin D. Larson
Summary: Anesthesiology has made significant progress in improving patient safety through advancements in drug development, technical innovations, and application of human factors and systems' research strategies. Anesthesia & Analgesia and the International Anesthesia Research Society continue to contribute to patient safety by disseminating practice standards, fostering innovation, and supporting research advancements. This review highlights topics published in Anesthesia & Analgesia that demonstrate the steady changes towards safer practices and discusses important activities by the IARS in advocating and elevating patient safety in the field.
ANESTHESIA AND ANALGESIA
(2022)
Editorial Material
Biochemistry & Molecular Biology
P. W. Barnes, T. M. Robson, P. J. Neale, C. E. Williamson, R. G. Zepp, S. Madronich, S. R. Wilson, A. L. Andrady, A. M. Heikkila, G. H. Bernhard, A. F. Bais, R. E. Neale, J. F. Bornman, M. A. K. Jansen, A. R. Klekociuk, J. Martinez-Abaigar, S. A. Robinson, Q-W Wang, A. T. Banaszak, D-P Haeder, S. Hylander, K. C. Rose, S-A Wangberg, B. Foereid, W-C Hou, R. Ossola, N. D. Paul, J. E. Ukpebor, M. P. S. Andersen, J. Longstreth, T. Schikowski, K. R. Solomon, B. Sulzberger, L. S. Bruckman, K. K. Pandey, C. C. White, L. Zhu, M. Zhu, P. J. Aucamp, J. B. Liley, R. L. McKenzie, M. Berwick, S. N. Byrne, L. M. Hollestein, R. M. Lucas, C. M. Olsen, L. E. Rhodes, S. Yazar, A. R. Young
Summary: The Environmental Effects Assessment Panel under the Montreal Protocol evaluates the environmental and health impacts of changes in the stratospheric ozone layer and UV radiation. The panel also discusses the interlinking effects between climate change and ozone depletion, and how they affect air quality, ecosystems, human health, and materials. The assessment highlights the potential impacts of extreme climate events on the biosphere and emphasizes the benefits of controlling the production of substances contributing to ozone depletion and climate change.
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
(2022)
Article
Chemistry, Physical
Mads Peter Sulbaek Andersen, Joanna Ohide, Theis Solling, Ole John Nielsen
Summary: In this study, FTIR-smog chamber techniques were used to investigate the reactions of CF3CN under various gas diluents. It was found that the atmospheric lifetime of CF3CN is determined by its reaction with OH, producing COF2 as a major product. The global warming potential of CF3CN was estimated to be 1030 for a 100 year time horizon.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Article
Environmental Sciences
Mads Peter Sulbaek Andersen, Ole John Nielsen
Summary: In this study, the photolysis products of CF3CHO were found to be mainly COF2, and no formation of HFC-23 was observed.
ATMOSPHERIC ENVIRONMENT
(2022)
Review
Anesthesiology
Jan F. A. Hendrickx, Ole John Nielsen, Stefan De Hert, Andre M. De Wolf
Summary: The EU has proposed to restrict or ban the use of desflurane without prior consultation with major stakeholders, which will impact daily anaesthesia practice. It is important to not overlook methods to reduce wasted potent inhaled anaesthetics despite restrictions or bans on one anaesthetic agent.
EUROPEAN JOURNAL OF ANAESTHESIOLOGY
(2022)
Article
Chemistry, Physical
Mads P. Sulbaek Andersen, Morten Frausig, Ole John Nielsen
Summary: The atmospheric chemistry of CCl2FCH2CF3 (HFCF-234fb) was studied using FT-IR/relative-rate methods. The rate coefficients of CCl2FCH2CF3 reacting with OH and Cl were determined, and the atmospheric lifetime of CCl2FCH2CF3 was estimated to be approximately 21 years.
INTERNATIONAL JOURNAL OF CHEMICAL KINETICS
(2023)
Letter
Multidisciplinary Sciences
Ole John Nielsen
Editorial Material
Chemistry, Physical
Indranil Dutta, Rajesh Kumar Parsapur, Sudipta Chatterjee, Amol M. Hengne, Davin Tan, Karthik Peramaiah, Theis I. Solling, Ole John Nielsen, Kuo-Wei Huang
ACS ENERGY LETTERS
(2023)
Article
Biochemistry & Molecular Biology
S. Madronich, B. Sulzberger, J. D. Longstreth, T. Schikowski, M. P. Sulbaek Andersen, K. R. Solomon, S. R. Wilson
Summary: Ultraviolet (UV) radiation drives the production of ozone and particulate matter, which are harmful to human health and the environment. The Montreal Protocol has successfully prevented major increases in UV radiation and air pollution. However, future scenarios of ozone recovery may have mixed effects on ground-level ozone and climate change can influence the transport of ozone into the troposphere. UV radiation also controls the amounts of chemicals in the atmosphere, including greenhouse gases and ozone-depleting substances, and their replacements may have unintended environmental impacts.
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
(2023)
Correction
Chemistry, Physical
Mads Peter Sulbaek Andersen, Joanna Ohide, Theis I. Solling, Ole John Nielsen
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Correction
Chemistry, Physical
Mads P. Sulbaek P. Andersen, Aleksandra Volkova, Sofie A. Hass, Jonathan W. Lengkong, Dvien Hovanessian, Theis I. Solling, Timothy J. Wallington, Ole J. Nielsen
Summary: Correction for 'Atmospheric chemistry of (Z)- and (E)-1,2-dichloroethene: kinetics and mechanisms of the reactions with Cl atoms, OH radicals, and O-3' by Mads P. Sulbaek Andersen et al., Phys. Chem. Chem. Phys., 2022, 24, 7356-7373, https://doi.org/10.1039/D1CP04877E.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Article
Environmental Sciences
Mads Peter Sulbaek Andersen, Sasha Madronich, Joanna May Ohide, Morten Frausig, Ole John Nielsen
Summary: In this study, the photolysis of CF3CHO and the quantum yields of various products were investigated. The results suggest that the photolytic production of CF3H may occur at stratospheric altitudes and is related to the source of CF3CHO.
ATMOSPHERIC ENVIRONMENT
(2023)
Article
Chemistry, Physical
Mads P. Sulbaek Andersen, Aleksandra Volkova, Sofie A. Hass, Jonathan W. Lengkong, Dvien Hovanessian, Theis Solling, Timothy J. Wallington, Ole J. Nielsen
Summary: This study investigates the kinetics and mechanisms of the oxidation of (Z)- and (E)-1,2-dichloroethene under atmospheric conditions. Smog chambers interfaced with in situ FT-IR detection were used to measure the rate constants of different reactions and study the formation of products. The results show that chlorine atom elimination and photochemical ozone creation potential play important roles in the atmospheric chemistry of these compounds.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)