标题
Glutamate metabolism and HIV-associated neurocognitive disorders
作者
关键词
HIV, Neuropathogenesis, HAND, Glutamate, Astrocytes
出版物
JOURNAL OF NEUROVIROLOGY
Volume 20, Issue 4, Pages 315-331
出版商
Springer Nature
发表日期
2014-05-27
DOI
10.1007/s13365-014-0258-2
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Lipoic acid increases glutamate uptake, glutamine synthetase activity and glutathione content in C6 astrocyte cell line
- (2013) Juliana Kleinkauf-Rocha et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- Cerebrospinal Fluid and Neuroimaging Biomarker Abnormalities Suggest Early Neurological Injury in a Subset of Individuals During Primary HIV Infection
- (2013) M. J. Peluso et al. JOURNAL OF INFECTIOUS DISEASES
- IL-1β and TNF-α induce neurotoxicity through glutamate production: a potential role for neuronal glutaminase
- (2013) Ling Ye et al. JOURNAL OF NEUROCHEMISTRY
- Targeting the Glutamatergic System for the Treatment of HIV-Associated Neurocognitive Disorders
- (2013) Michelle C. Potter et al. Journal of Neuroimmune Pharmacology
- Age-dependent molecular alterations in the autophagy pathway in HIVE patients and in a gp120 tg mouse model: reversal with beclin-1 gene transfer
- (2013) Jerel Fields et al. JOURNAL OF NEUROVIROLOGY
- Progressive cerebral injury in the setting of chronic HIV infection and antiretroviral therapy
- (2013) Assawin Gongvatana et al. JOURNAL OF NEUROVIROLOGY
- Regulation of astrocyte glutamine synthetase in epilepsy
- (2013) Tore Eid et al. NEUROCHEMISTRY INTERNATIONAL
- Chronic ceftriaxone treatment rescues hippocampal memory deficit in AQP4 knockout mice via activation of GLT-1
- (2013) Jun Yang et al. NEUROPHARMACOLOGY
- Activity and metabolism-related Ca2+ and mitochondrial dynamics in co-cultured human fetal cortical neurons and astrocytes
- (2013) W. Fu et al. NEUROSCIENCE
- BDNF Regulates the Expression and Distribution of Vesicular Glutamate Transporters in Cultured Hippocampal Neurons
- (2013) Carlos V. Melo et al. PLoS One
- Curcumin Protects Microglia and Primary Rat Cortical Neurons against HIV-1 gp120-Mediated Inflammation and Apoptosis
- (2013) Luyan Guo et al. PLoS One
- Curcumin is an inhibitor of calcium/calmodulin dependent protein kinase II
- (2012) M. Mayadevi et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Neurocognitive Impairment in HIV-Infected Naïve Patients with Advanced Disease: The Role of Virus and Intrathecal Immune Activation
- (2012) Monica Airoldi et al. Clinical & Developmental Immunology
- Gene expression of glutamate metabolizing enzymes in the hippocampal formation in human temporal lobe epilepsy
- (2012) Tore Eid et al. EPILEPSIA
- Tianeptine modulates amygdalar glutamate neurochemistry and synaptic proteins in rats subjected to repeated stress
- (2012) Gerardo G. Piroli et al. EXPERIMENTAL NEUROLOGY
- Neuronal toxicity in HIV CNS disease
- (2012) Jane Kovalevich et al. Future Virology
- Central Nervous System Viral Invasion and Inflammation During Acute HIV Infection
- (2012) Victor Valcour et al. JOURNAL OF INFECTIOUS DISEASES
- The chemokine, macrophage inflammatory protein-2γ, reduces the expression of glutamate transporter-1 on astrocytes and increases neuronal sensitivity to glutamate excitotoxicity
- (2012) Jie Fang et al. Journal of Neuroinflammation
- L-glutamate released from activated microglia downregulates astrocytic L-glutamate transporter expression in neuroinflammation: the ‘collusion’ hypothesis for increased extracellular L-glutamate concentration in neuroinflammation
- (2012) Junpei Takaki et al. Journal of Neuroinflammation
- Effects of fluoxetine, tianeptine and olanzapine on unpredictable chronic mild stress-induced depression-like behavior in mice
- (2012) Oguz Mutlu et al. LIFE SCIENCES
- siRNA knock down of glutamate dehydrogenase in astrocytes affects glutamate metabolism leading to extensive accumulation of the neuroactive amino acids glutamate and aspartate
- (2012) Dorte M. Skytt et al. NEUROCHEMISTRY INTERNATIONAL
- The complex regulation of human glud1 and glud2 glutamate dehydrogenases and its implications in nerve tissue biology
- (2012) Cleanthe Spanaki et al. NEUROCHEMISTRY INTERNATIONAL
- Neurotoxins released from interferon-gamma-stimulated human astrocytes
- (2012) M. Lee et al. NEUROSCIENCE
- Interferon-α Regulates Glutaminase 1 Promoter through STAT1 Phosphorylation: Relevance to HIV-1 Associated Neurocognitive Disorders
- (2012) Lixia Zhao et al. PLoS One
- The National NeuroAIDS Tissue Consortium Brain Gene Array: Two Types of HIV-Associated Neurocognitive Impairment
- (2012) Benjamin B. Gelman et al. PLoS One
- Change in Brain Magnetic Resonance Spectroscopy after Treatment during Acute HIV Infection
- (2012) Napapon Sailasuta et al. PLoS One
- Glutathione synthesis and its role in redox signaling
- (2012) Hongqiao Zhang et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Persistence of HIV-associated cognitive impairment, inflammation, and neuronal injury in era of highly active antiretroviral treatment
- (2011) Jarek Harezlak et al. AIDS
- IFN- Mediates Enhancement of HIV Replication in Astrocytes by Inducing an Antagonist of the -Catenin Pathway (DKK1) in a STAT 3-Dependent Manner
- (2011) W. Li et al. JOURNAL OF IMMUNOLOGY
- Reversible dementia in a patient with central nervous system escape of human immunodeficiency virus
- (2011) Isaac I. Bogoch et al. JOURNAL OF INFECTION
- Central Nervous System Immune Activation Characterizes Primary Human Immunodeficiency Virus 1 Infection Even in Participants With Minimal Cerebrospinal Fluid Viral Burden
- (2011) Serena Spudich et al. JOURNAL OF INFECTIOUS DISEASES
- HIV-1 and IL-1β regulate astrocytic CD38 through mitogen-activated protein kinases and nuclear factor-κB signaling mechanisms
- (2011) Manmeet K Mamik et al. Journal of Neuroinflammation
- Glutaminase Dysregulation in HIV-1-Infected Human Microglia Mediates Neurotoxicity: Relevant to HIV-1-Associated Neurocognitive Disorders
- (2011) Y. Huang et al. JOURNAL OF NEUROSCIENCE
- Human Immunodeficiency Virus Infection of Human Astrocytes Disrupts Blood-Brain Barrier Integrity by a Gap Junction-Dependent Mechanism
- (2011) E. A. Eugenin et al. JOURNAL OF NEUROSCIENCE
- Cerebral metabolite abnormalities in human immunodeficiency virus are associated with cortical and subcortical volumes
- (2011) Ronald A Cohen et al. JOURNAL OF NEUROVIROLOGY
- Protein changes in CSF of HIV-infected patients: evidence for loss of neuroprotection
- (2011) Rick B. Meeker et al. JOURNAL OF NEUROVIROLOGY
- HIV-associated dementia in the era of highly active antiretroviral therapy (HAART)
- (2011) Chenglai Xia et al. MICROBES AND INFECTION
- Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons
- (2011) Sherry Dadsetan et al. NEUROCHEMISTRY INTERNATIONAL
- HIV-1 gp120 induces antioxidant response element-mediated expression in primary astrocytes: Role in HIV associated neurocognitive disorder
- (2011) Pichili Vijaya Bhaskar Reddy et al. NEUROCHEMISTRY INTERNATIONAL
- Microglia activation triggers astrocyte-mediated modulation of excitatory neurotransmission
- (2011) O. Pascual et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HIV-1 Replication in the Central Nervous System Occurs in Two Distinct Cell Types
- (2011) Gretja Schnell et al. PLoS Pathogens
- The protective effect of tianeptine on Gp120-induced apoptosis in astroglial cells: role of GS and NOS, and NF-κB suppression
- (2010) Elzbieta Janda et al. BRITISH JOURNAL OF PHARMACOLOGY
- Astrocytic glutamate transporter-dependent neuroprotection against glutamate toxicity: An in vitro study of maslinic acid
- (2010) Yisong Qian et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Depletion of GSH in glial cells induces neurotoxicity: relevance to aging and degenerative neurological diseases
- (2010) Moonhee Lee et al. FASEB JOURNAL
- Memantine for AIDS Dementia Complex: Open-Label Report of ACTG 301
- (2010) Yu Zhao et al. HIV CLINICAL TRIALS
- HIV-1 phylogenetic analysis shows HIV-1 transits through the meninges to brain and peripheral tissues
- (2010) Susanna L. Lamers et al. INFECTION GENETICS AND EVOLUTION
- Brain Glutamine Synthesis Requires Neuronal Aspartate: A Commentary
- (2010) Leif Hertz JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Brain Glutamine Synthesis Requires Neuronal-Born Aspartate as Amino Donor for Glial Glutamate Formation
- (2010) Beatriz Pardo et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Lower brain glutamate is associated with cognitive deficits in HIV patients: A new mechanism for HIV-associated neurocognitive disorder
- (2010) Thomas Ernst et al. JOURNAL OF MAGNETIC RESONANCE IMAGING
- Neurometabolite Abnormalities in Simian Immunodeficiency Virus-Infected Macaques with Chronic Morphine Administration
- (2010) Christine C. Cloak et al. Journal of Neuroimmune Pharmacology
- Cliniconeuropathologic correlates of human immunodeficiency virus in the era of antiretroviral therapy
- (2010) I Everall et al. JOURNAL OF NEUROVIROLOGY
- Neurocognitive functioning in acute or early HIV infection
- (2010) David J. Moore et al. JOURNAL OF NEUROVIROLOGY
- HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors
- (2010) Robert K. Heaton et al. JOURNAL OF NEUROVIROLOGY
- STAT3 inhibitors attenuate interferon-γ-induced neurotoxicity and inflammatory molecule production by human astrocytes
- (2010) Sadayuki Hashioka et al. NEUROBIOLOGY OF DISEASE
- Glutamine synthetase down-regulation reduces astrocyte protection against glutamate excitotoxicity to neurons
- (2010) Jian Zou et al. NEUROCHEMISTRY INTERNATIONAL
- Neurologic disease burden in treated HIV/AIDS predicts survival: A population-based study
- (2010) P. Vivithanaporn et al. NEUROLOGY
- Metabolic Control of Vesicular Glutamate Transport and Release
- (2010) Narinobu Juge et al. NEURON
- Characterisation of the Expression of NMDA Receptors in Human Astrocytes
- (2010) Ming-Chak Lee et al. PLoS One
- IL-6 stimulates system A amino acid transporter activity in trophoblast cells through STAT3 and increased expression of SNAT2
- (2009) H. N. Jones et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia
- (2009) Melissa J. Churchill et al. ANNALS OF NEUROLOGY
- In vivo proton magnetic resonance spectroscopy reveals region specific metabolic responses to SIV infection in the macaque brain
- (2009) Eva-Maria Ratai et al. BMC NEUROSCIENCE
- High extracellular glutamate modulates expression of glutamate transporters and glutamine synthetase in cultured astrocytes
- (2009) Claudia Lehmann et al. BRAIN RESEARCH
- Tumor necrosis factor-α modulates glutamate transport in the CNS and is a critical determinant of outcome from viral encephalomyelitis
- (2009) Jessica Carmen et al. BRAIN RESEARCH
- HIV-1 associated dementia: update on pathological mechanisms and therapeutic approaches
- (2009) Marcus Kaul CURRENT OPINION IN NEUROLOGY
- Gain-of-function variant in GLUD2 glutamate dehydrogenase modifies Parkinson's disease onset
- (2009) Andreas Plaitakis et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- In vitroglutaminase regulation and mechanisms of glutamate generation in HIV-1-infected macrophage
- (2009) Nathan Erdmann et al. JOURNAL OF NEUROCHEMISTRY
- Reduced Expression of Excitatory Amino Acid Transporter 2 and Diffuse Microglial Activation in the Cerebral Cortex in AIDS Cases With or Without HIV Encephalitis
- (2009) Hui Qin Xing et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Interferon- Causes Neuronal Dysfunction in Encephalitis
- (2009) A. R. Sas et al. JOURNAL OF NEUROSCIENCE
- CD38 regulation in activated astrocytes: Implications for neuroinflammation and HIV-1 brain infection
- (2009) Wei Kou et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Curcumin improves spatial memory impairment induced by human immunodeficiency virus type 1 glycoprotein 120 V3 loop peptide in rats
- (2009) Hongmei Tang et al. LIFE SCIENCES
- Selective up-regulation of GLT-1 in cultured astrocytes exposed to soluble mediators released by activated microglia
- (2009) Sébastien Tilleux et al. NEUROCHEMISTRY INTERNATIONAL
- Responses of astrocyte to simultaneous glutamate and arachidonic acid treatment
- (2009) Zhen Yu Xu et al. NEUROCHEMISTRY INTERNATIONAL
- Changes in MRS neuronal markers and T cell phenotypes observed during early HIV infection
- (2009) M. R. Lentz et al. NEUROLOGY
- Dynamics of cognitive change in impaired HIV-positive patients initiating antiretroviral therapy
- (2009) L. A. Cysique et al. NEUROLOGY
- Neuroprotective and Antiinflammatory Properties of a Novel Demethylated Curcuminoid
- (2008) Savita Khanna et al. ANTIOXIDANTS & REDOX SIGNALING
- Curcumin protects against glutamate excitotoxicity in rat cerebral cortical neurons by increasing brain-derived neurotrophic factor level and activating TrkB
- (2008) Rui Wang et al. BRAIN RESEARCH
- Proinflammatory cytokines and HIV-1 synergistically enhance CXCL10 expression in human astrocytes
- (2008) Rachel Williams et al. GLIA
- Mechanism of Ceftriaxone Induction of Excitatory Amino Acid Transporter-2 Expression and Glutamate Uptake in Primary Human Astrocytes
- (2008) Seok-Geun Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Down-regulation of astrocytic GLAST by microglia-related inflammation is abrogated in dibutyryl cAMP-differentiated cultures
- (2008) Sébastien Tilleux et al. JOURNAL OF NEUROCHEMISTRY
- HIV-infected macrophages mediate neuronal apoptosis through mitochondrial glutaminase
- (2008) Changhai Tian et al. JOURNAL OF NEUROCHEMISTRY
- Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway
- (2008) Teresa F Pais et al. Journal of Neuroinflammation
- Factor analysis reveals differences in brain metabolism in macaques with SIV/AIDS and those with SIV-induced encephalitis
- (2008) Margaret R. Lentz et al. NMR IN BIOMEDICINE
- Evidence of reduced glutamate in the frontal lobe of HIV-seropositive patients
- (2008) Napapon Sailasuta et al. NMR IN BIOMEDICINE
- HIV's double strike at the brain: neuronal toxicity and compromised neurogenesis
- (2007) Marcus Kaul Frontiers in Bioscience-Landmark
- Proposed cycles for functional glutamate trafficking in synaptic neurotransmission
- (2007) Paul K. Maciejewski et al. NEUROCHEMISTRY INTERNATIONAL
- Mechanisms of glutamate release from astrocytes
- (2007) Erik B. Malarkey et al. NEUROCHEMISTRY INTERNATIONAL
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