Central but not systemic administration of XPro1595 is therapeutic following moderate spinal cord injury in mice

Knockdown of Interleukin-1 Receptor Type-1 on Endothelial Cells Attenuated Stress-Induced Neuroinflammation and Prevented Anxiety-Like Behavior

(2014) E. S. Wohleb et al.   JOURNAL OF NEUROSCIENCE

Symptoms of Depression Over Time in Adults With Pediatric-Onset Spinal Cord Injury

(2013) Alicia M. January et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

Analysis of cognition, motor performance and anxiety in young and aged tumor necrosis factor alpha receptor 1 and 2 deficient mice

(2013) Petrus J.W. Naude et al.   BEHAVIOURAL BRAIN RESEARCH

Astrocyte-specific activation of TNFR2 promotes oligodendrocyte maturation by secretion of leukemia inhibitory factor

(2013) Roman Fischer et al.   GLIA

Astrocytes play a key role in EAE pathophysiology by orchestrating in the CNS the inflammatory response of resident and peripheral immune cells and by suppressing remyelination

(2013) Roberta Brambilla et al.   GLIA

Inhibition of astroglial NF-kappaB enhances oligodendrogenesis following spinal cord injury

(2013) Valerie Bracchi-Ricard et al.   Journal of Neuroinflammation

Inhibition of NADPH Oxidase Activation in Oligodendrocytes Reduces Cytotoxicity Following Trauma

(2013) Joshua T. Johnstone et al.   PLoS One

Inflammatory Cytokines in Experimental and Human Stroke

(2012) Kate Lykke Lambertsen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Chronic dim light at night provokes reversible depression-like phenotype: possible role for TNF

(2012) T A Bedrosian et al.   MOLECULAR PSYCHIATRY

Genetic KCa3.1-Deficiency Produces Locomotor Hyperactivity and Alterations in Cerebral Monoamine Levels

(2012) Kate Lykke Lambertsen et al.   PLoS One

Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination

(2011) Roberta Brambilla et al.   BRAIN

Transmembrane tumour necrosis factor is neuroprotective and regulates experimental autoimmune encephalomyelitis via neuronal nuclear factor-κB

(2011) Era Taoufik et al.   BRAIN

Inflammation and axon regeneration

(2011) Larry I. Benowitz et al.   CURRENT OPINION IN NEUROLOGY

Tumor necrosis factor alpha (TNF-α), anti-TNF-α and demyelination revisited: An ongoing story

(2011) Ana Caminero et al.   JOURNAL OF NEUROIMMUNOLOGY

A TNF Receptor 2 Selective Agonist Rescues Human Neurons from Oxidative Stress-Induced Cell Death

(2011) Roman Fischer et al.   PLoS One

Infliximab, a TNF-alpha antagonist treatment in patients with ankylosing spondylitis: the impact on depression, anxiety and quality of life level

(2010) I. Ertenli et al.   RHEUMATOLOGY INTERNATIONAL

Iron is essential for oligodendrocyte genesis following intraspinal macrophage activation

(2009) David L. Schonberg et al.   EXPERIMENTAL NEUROLOGY

Microglia Protect Neurons against Ischemia by Synthesis of Tumor Necrosis Factor

(2009) K. L. Lambertsen et al.   JOURNAL OF NEUROSCIENCE

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Damage control in the nervous system: beware the immune system in spinal cord injury

(2009) Phillip Popovich et al.   NATURE MEDICINE

Anti-TNF biologic agents: still the therapy of choice for rheumatoid arthritis

(2009) Peter C. Taylor et al.   Nature Reviews Rheumatology

Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology

(2009) Fiona E. McAlpine et al.   NEUROBIOLOGY OF DISEASE

Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice

(2008) Bettina H Clausen et al.   Journal of Neuroinflammation

TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease

(2008) Melissa K McCoy et al.   Journal of Neuroinflammation

Cell Death after Spinal Cord Injury Is Exacerbated by Rapid TNF -Induced Trafficking of GluR2-Lacking AMPARs to the Plasma Membrane

(2008) A. R. Ferguson et al.   JOURNAL OF NEUROSCIENCE

Intranigral Lentiviral Delivery of Dominant-negative TNF Attenuates Neurodegeneration and Behavioral Deficits in Hemiparkinsonian rats

(2008) Melissa K McCoy et al.   MOLECULAR THERAPY

Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury

(2007) Dustin J. Donnelly et al.   EXPERIMENTAL NEUROLOGY