Delineating HIV-Associated Neurocognitive Disorders Using Transgenic Models: The Neuropathogenic Actions of Vpr

NeuroAIDS: An Evolving Epidemic

(2014) Christopher Power et al.   CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES

Immune reconstitution inflammatory syndrome and the central nervous system

(2011) Tory Johnson et al.   CURRENT OPINION IN NEUROLOGY

Vpr-Host Interactions During HIV-1 Viral Life Cycle

(2011) Richard Y. Zhao et al.   Journal of Neuroimmune Pharmacology

Hepatitis D revival

(2011) Heiner Wedemeyer   LIVER INTERNATIONAL

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

(2011) Nadine Laguette et al.   NATURE

Modulation of HIV-1-host interaction: role of the Vpu accessory protein

(2011) Mathieu Dubé et al.   Retrovirology

Interactions between human immunodeficiency virus (HIV)-1 Vpr expression and innate immunity influence neurovirulence

(2011) Hong Na et al.   Retrovirology

Innate immunity and chronic immune activation in HCV/HIV-1 co-infection

(2010) Veronica D. Gonzalez et al.   CLINICAL IMMUNOLOGY

HIV-1 viral protein R causes peripheral nervous system injury associated with in vivo neuropathic pain

(2010) Shaona Acharjee et al.   FASEB JOURNAL

MicroRNA profiling reveals new aspects of HIV neurodegeneration: caspase-6 regulates astrocyte survival

(2010) Farshid Noorbakhsh et al.   FASEB JOURNAL

Activation of brain macrophages/microglia cells in hepatitis C infection

(2010) J. Wilkinson et al.   GUT

HIV-1 Vpr Loads Uracil DNA Glycosylase-2 onto DCAF1, a Substrate Recognition Subunit of a Cullin 4A-RING E3 Ubiquitin Ligase for Proteasome-dependent Degradation

(2010) Jinwoo Ahn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1 Vpu targets cell surface markers CD4 and BST-2 through distinct mechanisms

(2010) Amy Andrew et al.   MOLECULAR ASPECTS OF MEDICINE

Hepatitis C Virus Core Protein Induces Neuroimmune Activation and Potentiates Human Immunodeficiency Virus-1 Neurotoxicity

(2010) Pornpun Vivithanaporn et al.   PLoS One

Molecular mechanisms of neuroinvasion by monocytes-macrophages in HIV-1 infection

(2010) Gabriel Gras et al.   Retrovirology

BST-2/tetherin: a new component of the innate immune response to enveloped viruses

(2010) David T. Evans et al.   TRENDS IN MICROBIOLOGY

Human immunodeficiency virus type 1 Vpr: oligomerization is an essential feature for its incorporation into virus particles

(2010) Narasimhan J Venkatachari et al.   Virology Journal

Formation of Mobile Chromatin-Associated Nuclear Foci Containing HIV-1 Vpr and VPRBP Is Critical for the Induction of G2 Cell Cycle Arrest

(2010) Jean-Philippe Belzile et al.   PLoS Pathogens

Human cellular restriction factors that target HIV-1 replication

(2009) Klaus Strebel et al.   BMC Medicine

CXCR3 activation by lentivirus infection suppresses neuronal autophagy: neuroprotective effects of antiretroviral therapy

(2009) Yu Zhu et al.   FASEB JOURNAL

Human immunodeficiency virus type 1 Vpr: functions and molecular interactions

(2009) B. Romani et al.   JOURNAL OF GENERAL VIROLOGY

CNS Inflammation and Macrophage/Microglial Biology Associated with HIV-1 Infection

(2009) Anjana Yadav et al.   Journal of Neuroimmune Pharmacology

Human Immunodeficiency Virus Type 1 Mediates Global Disruption of Innate Antiviral Signaling and Immune Defenses within Infected Cells

(2009) B. P. Doehle et al.   JOURNAL OF VIROLOGY

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

(2009) Gillian I Rice et al.   NATURE GENETICS

INFLAMMATORY PSEUDOTUMOR ASSOCIATED WITH HIV, JCV, AND IMMUNE RECONSTITUTION SYNDROME

(2009) A. Gonzalez-Duarte et al.   NEUROLOGY

Deciphering complex mechanisms in neurodegenerative diseases: the advent of systems biology

(2009) Farshid Noorbakhsh et al.   TRENDS IN NEUROSCIENCES

Natural history of hepatitis C virus infection in HIV-infected individuals and the impact of HIV in the era of highly active antiretroviral therapy: a meta-analysis

(2008) Hla-Hla Thein et al.   AIDS

Validation of the CNS Penetration-Effectiveness Rank for Quantifying Antiretroviral Penetration Into the Central Nervous System

(2008) Scott Letendre   ARCHIVES OF NEUROLOGY

Assembly with the Cul4A-DDB1DCAF1Ubiquitin Ligase Protects HIV-1 Vpr from Proteasomal Degradation

(2008) Erwann Le Rouzic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased In Vivo Activation of Microglia and Astrocytes in the Brains of Mice Transgenic for an Infectious R5 Human Immunodeficiency Virus Type 1 Provirus and for CD4-Specific Expression of Human Cyclin T1 in Response to Stimulation by Lipopolysaccharides

(2008) J. Sun et al.   JOURNAL OF VIROLOGY

Hepatitis C Virus Neuroinvasion: Identification of Infected Cells

(2008) J. Wilkinson et al.   JOURNAL OF VIROLOGY

From endoplasmic-reticulum stress to the inflammatory response

(2008) Kezhong Zhang et al.   NATURE

HIV Infection of the Central Nervous System: Clinical Features and Neuropathogenesis

(2008) Lysa Boissé et al.   NEUROLOGIC CLINICS

Lentiviral Vpx Accessory Factor Targets VprBP/DCAF1 Substrate Adaptor for Cullin 4 E3 Ubiquitin Ligase to Enable Macrophage Infection

(2008) Smita Srivastava et al.   PLoS Pathogens

HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation

(2007) Atsushi Okumura et al.   VIROLOGY