Vpr-Host Interactions During HIV-1 Viral Life Cycle

HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells

(2010) Alexandra Snyder et al.   AIDS

Immune Evasion and Counteraction of Restriction Factors by HIV-1 and Other Primate Lentiviruses

(2010) Frank Kirchhoff   Cell Host & Microbe

HIV-1 viral protein R causes peripheral nervous system injury associated with in vivo neuropathic pain

(2010) Shaona Acharjee et al.   FASEB JOURNAL

HIV-1 Vpr Loads Uracil DNA Glycosylase-2 onto DCAF1, a Substrate Recognition Subunit of a Cullin 4A-RING E3 Ubiquitin Ligase for Proteasome-dependent Degradation

(2010) Jinwoo Ahn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1 Vpr Induces the K48-Linked Polyubiquitination and Proteasomal Degradation of Target Cellular Proteins To Activate ATR and Promote G2 Arrest

(2010) J.-P. Belzile et al.   JOURNAL OF VIROLOGY

HIV-1 Replication through hHR23A-Mediated Interaction of Vpr with 26S Proteasome

(2010) Ge Li et al.   PLoS One

PP2A1 Binding, Cell Transducing and Apoptotic Properties of Vpr77–92: A New Functional Domain of HIV-1 Vpr Proteins

(2010) Angélique N. Godet et al.   PLoS One

Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage

(2010) Evelyn M Kilareski et al.   Retrovirology

Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R

(2010) Ge Li et al.   Retrovirology

Formation of Mobile Chromatin-Associated Nuclear Foci Containing HIV-1 Vpr and VPRBP Is Critical for the Induction of G2 Cell Cycle Arrest

(2010) Jean-Philippe Belzile et al.   PLoS Pathogens

HIV-1 Viral Protein R (VPR) and its Interactions with Host Cell

(2009) Ge Li et al.   CURRENT HIV RESEARCH

Human immunodeficiency virus type 1 Vpr: functions and molecular interactions

(2009) B. Romani et al.   JOURNAL OF GENERAL VIROLOGY

Analysis of the Viral Elements Required in the Nuclear Import of HIV-1 DNA

(2009) L. Riviere et al.   JOURNAL OF VIROLOGY

Uracil DNA Glycosylase 2 negatively regulates HIV-1 LTR transcription

(2009) David Fenard et al.   NUCLEIC ACIDS RESEARCH

HIV-1 Vpr-induced cell death in Schizosaccharomyces pombe is reminiscent of apoptosis

(2008) Sylvain Huard et al.   CELL RESEARCH

HIV-1 Vpr: Mechanisms of G2 arrest and apoptosis

(2008) Joshua L. Andersen et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Human Immunodeficiency Virus Type 1 Vpr Binds to the N Lobe of the Wee1 Kinase Domain and Enhances Kinase Activity for Cdc2

(2008) M. Kamata et al.   JOURNAL OF VIROLOGY

Impaired nuclear import and viral incorporation of Vpr derived from a HIV long-term non-progressor

(2008) Leon Caly et al.   Retrovirology