标题
mTOR complex 1: a key player in neuroadaptations induced by drugs of abuse
作者
关键词
-
出版物
JOURNAL OF NEUROCHEMISTRY
Volume 130, Issue 2, Pages 172-184
出版商
Wiley
发表日期
2014-03-26
DOI
10.1111/jnc.12725
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A Central Role for mTOR in Lipid Homeostasis
- (2013) Dudley W. Lamming et al. Cell Metabolism
- Rapamycin prevents drug seeking via disrupting reconsolidation of reward memory in rats
- (2013) Jue Lin et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Regulation of mTORC1 and its impact on gene expression at a glance
- (2013) M. Laplante et al. JOURNAL OF CELL SCIENCE
- mTOR kinase structure, mechanism and regulation
- (2013) Haijuan Yang et al. NATURE
- Disruption of alcohol-related memories by mTORC1 inhibition prevents relapse
- (2013) Segev Barak et al. NATURE NEUROSCIENCE
- mTOR complexes in neurodevelopmental and neuropsychiatric disorders
- (2013) Mauro Costa-Mattioli et al. NATURE NEUROSCIENCE
- Dissociation of the Pharmacological Effects of THC by mTOR Blockade
- (2013) Emma Puighermanal et al. NEUROPSYCHOPHARMACOLOGY
- Macroautophagy can press a brake on presynaptic neurotransmission
- (2012) Ciara A. Torres et al. Autophagy
- Blocking mTORC1 activity by rapamycin leads to impairment of spatial memory retrieval but not acquisition in C57BL/6J mice
- (2012) Alev Deli et al. BEHAVIOURAL BRAIN RESEARCH
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- Long-Distance Growth and Connectivity of Neural Stem Cells after Severe Spinal Cord Injury
- (2012) Paul Lu et al. CELL
- Methamphetamine-induced changes in the mice hippocampal neuropeptide Y system: implications for memory impairment
- (2012) Joana Gonçalves et al. JOURNAL OF NEUROCHEMISTRY
- Multiple Roles for Mammalian Target of Rapamycin Signaling in Both Glutamatergic and GABAergic Synaptic Transmission
- (2012) M. C. Weston et al. JOURNAL OF NEUROSCIENCE
- Neuronal Stimulation Induces Autophagy in Hippocampal Neurons That Is Involved in AMPA Receptor Degradation after Chemical Long-Term Depression
- (2012) M. Shehata et al. JOURNAL OF NEUROSCIENCE
- The Small G Protein H-Ras in the Mesolimbic System Is a Molecular Gateway to Alcohol-Seeking and Excessive Drinking Behaviors
- (2012) S. Ben Hamida et al. JOURNAL OF NEUROSCIENCE
- A unifying model for mTORC1-mediated regulation of mRNA translation
- (2012) Carson C. Thoreen et al. NATURE
- Regulation of Presynaptic Neurotransmission by Macroautophagy
- (2012) Daniela Hernandez et al. NEURON
- Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice
- (2012) J. Halloran et al. NEUROSCIENCE
- Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity
- (2012) D. W. Lamming et al. SCIENCE
- mTOR: on target for novel therapeutic strategies in the nervous system
- (2012) Kenneth Maiese et al. TRENDS IN MOLECULAR MEDICINE
- An Emerging Role for the Mammalian Target of Rapamycin in “Pathological” Protein Translation: Relevance to Cocaine Addiction
- (2012) Christopher V. Dayas et al. Frontiers in Pharmacology
- Rapamycin attenuates the expression of cocaine-induced place preference and behavioral sensitization
- (2011) Jeffrey Bailey et al. ADDICTION BIOLOGY
- Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling
- (2011) Smita Majumder et al. AGING CELL
- Impairment of object recognition memory by rapamycin inhibition of mTOR in the amygdala or hippocampus around the time of learning or reactivation
- (2011) Paulo F.C. Jobim et al. BEHAVIOURAL BRAIN RESEARCH
- AKT Signaling Pathway in the Nucleus Accumbens Mediates Excessive Alcohol Drinking Behaviors
- (2011) Jérémie Neasta et al. BIOLOGICAL PSYCHIATRY
- Suppression of PKR Promotes Network Excitability and Enhanced Cognition by Interferon-γ-Mediated Disinhibition
- (2011) Ping Jun Zhu et al. CELL
- mTOR signaling in disease
- (2011) Eva Dazert et al. CURRENT OPINION IN CELL BIOLOGY
- Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models
- (2011) Andrii Domanskyi et al. FASEB JOURNAL
- Local RNA Translation at the Synapse and in Disease
- (2011) L. Liu-Yesucevitz et al. JOURNAL OF NEUROSCIENCE
- NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses
- (2011) Anita E. Autry et al. NATURE
- Control of autophagy as a therapy for neurodegenerative disease
- (2011) Harry Harris et al. Nature Reviews Neurology
- Inhibition of mTOR by rapamycin in the amygdala or hippocampus impairs formation and reconsolidation of inhibitory avoidance memory
- (2011) Paulo F.C. Jobim et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Role for mTOR Signaling and Neuronal Activity in Morphine-Induced Adaptations in Ventral Tegmental Area Dopamine Neurons
- (2011) Michelle S. Mazei-Robison et al. NEURON
- Consolidation and reconsolidation of contextual fear memory requires mammalian target of rapamycin-dependent translation in the dorsal hippocampus
- (2011) G.M. Gafford et al. NEUROSCIENCE
- Drug Wanting: Behavioral Sensitization and Relapse to Drug-Seeking Behavior
- (2011) J. D. Steketee et al. PHARMACOLOGICAL REVIEWS
- Phosphoproteomic Profiling of In Vivo Signaling in Liver by the Mammalian Target of Rapamycin Complex 1 (mTORC1)
- (2011) Gokhan Demirkan et al. PLoS One
- Selective pharmacogenetic inhibition of mammalian target of Rapamycin complex I (mTORC1) blocks long-term synaptic plasticity and memory storage
- (2011) Loredana Stoica et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder
- (2011) Courtney S. Jernigan et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Phosphoproteomic Analysis Identifies Grb10 as an mTORC1 Substrate That Negatively Regulates Insulin Signaling
- (2011) Y. Yu et al. SCIENCE
- The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling
- (2011) P. P. Hsu et al. SCIENCE
- The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
- (2011) Michelle C. Mendoza et al. TRENDS IN BIOCHEMICAL SCIENCES
- Autophagy gets a brake
- (2010) Itay Koren et al. Autophagy
- PTEN/mTOR and axon regeneration
- (2010) Kevin K. Park et al. EXPERIMENTAL NEUROLOGY
- Nucleus Accumbens Core Mammalian Target of Rapamycin Signaling Pathway Is Critical for Cue-Induced Reinstatement of Cocaine Seeking in Rats
- (2010) X. Wang et al. JOURNAL OF NEUROSCIENCE
- Pathogenic Lysosomal Depletion in Parkinson's Disease
- (2010) B. Dehay et al. JOURNAL OF NEUROSCIENCE
- Long-Lasting Adaptations of the NR2B-Containing NMDA Receptors in the Dorsomedial Striatum Play a Crucial Role in Alcohol Consumption and Relapse
- (2010) J. Wang et al. JOURNAL OF NEUROSCIENCE
- Differing effects of systemically administered rapamycin on consolidation and reconsolidation of context vs. cued fear memories
- (2010) E. M. Glover et al. LEARNING & MEMORY
- Structure of the Human mTOR Complex I and Its Implications for Rapamycin Inhibition
- (2010) Calvin K. Yip et al. MOLECULAR CELL
- PTEN deletion enhances the regenerative ability of adult corticospinal neurons
- (2010) Kai Liu et al. NATURE NEUROSCIENCE
- mTOR: from growth signal integration to cancer, diabetes and ageing
- (2010) Roberto Zoncu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Activation of phosphatidylinositol 3-kinase/Akt-mammalian target of Rapamycin signaling pathway in the hippocampus is essential for the acquisition of morphine-induced place preference in rats
- (2010) Yue Cui et al. NEUROSCIENCE
- Inhibition of the mammalian target of rapamycin pathway by rapamycin blocks cocaine-induced locomotor sensitization
- (2010) J. Wu et al. NEUROSCIENCE
- Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy
- (2010) C A Sparks et al. ONCOGENE
- Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease
- (2010) Patricia Spilman et al. PLoS One
- Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders
- (2010) J. Neasta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
- (2010) N. Li et al. SCIENCE
- The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens
- (2010) Scott J. Russo et al. TRENDS IN NEUROSCIENCES
- Integration of Clearance Mechanisms: The Proteasome and Autophagy
- (2010) E. Wong et al. Cold Spring Harbor Perspectives in Biology
- Dissecting the role of mTOR: Lessons from mTOR inhibitors
- (2009) Ryan J.O. Dowling et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Biphasic Activation of the mTOR Pathway in the Gustatory Cortex Is Correlated with and Necessary for Taste Learning
- (2009) K. Belelovsky et al. JOURNAL OF NEUROSCIENCE
- Binge Drinking Upregulates Accumbens mGluR5-Homer2-PI3K Signaling: Functional Implications for Alcoholism
- (2009) D. K. Cozzoli et al. JOURNAL OF NEUROSCIENCE
- Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy
- (2009) Nao Hosokawa et al. MOLECULAR BIOLOGY OF THE CELL
- Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling
- (2009) Emma Puighermanal et al. NATURE NEUROSCIENCE
- Molecular mechanisms of mTOR-mediated translational control
- (2009) Xiaoju Max Ma et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Translational Control of Long-Lasting Synaptic Plasticity and Memory
- (2009) Mauro Costa-Mattioli et al. NEURON
- Neurocircuitry of Addiction
- (2009) George F Koob et al. NEUROPSYCHOPHARMACOLOGY
- Alcoholism: A Systems Approach From Molecular Physiology to Addictive Behavior
- (2009) Rainer Spanagel PHYSIOLOGICAL REVIEWS
- BDNF Activates mTOR to Regulate GluR1 Expression Required for Memory Formation
- (2009) Leandro Slipczuk et al. PLoS One
- Inhibition of mTOR Signaling in Parkinson's Disease Prevents L-DOPA-Induced Dyskinesia
- (2009) E. Santini et al. Science Signaling
- mTOR signaling: At the crossroads of plasticity, memory and disease
- (2009) Charles A. Hoeffer et al. TRENDS IN NEUROSCIENCES
- SKAR Links Pre-mRNA Splicing to mTOR/S6K1-Mediated Enhanced Translation Efficiency of Spliced mRNAs
- (2008) Xiaoju Max Ma et al. CELL
- Forskolin induction of late-LTP and up-regulation of 5 TOP mRNAs translation via mTOR, ERK, and PI3K in hippocampal pyramidal cells
- (2008) Delphine Gobert et al. JOURNAL OF NEUROCHEMISTRY
- Role of the phosphoinositide 3-kinase-Akt-mammalian target of the rapamycin signaling pathway in long-term potentiation and trace fear conditioning memory in rat medial prefrontal cortex
- (2008) L. Sui et al. LEARNING & MEMORY
- Systemic inhibition of mammalian target of rapamycin inhibits fear memory reconsolidation
- (2008) Jacqueline Blundell et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Removal of FKBP12 Enhances mTOR-Raptor Interactions, LTP, Memory, and Perseverative/Repetitive Behavior
- (2008) Charles A. Hoeffer et al. NEURON
- Role of mTOR in physiology and pathology of the nervous system
- (2007) Lukasz Swiech et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- On the participation of mTOR in recognition memory
- (2007) Jociane C. Myskiw et al. NEUROBIOLOGY OF LEARNING AND MEMORY
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