标题
Modeling human neurological disorders with induced pluripotent stem cells
作者
关键词
-
出版物
JOURNAL OF NEUROCHEMISTRY
Volume 129, Issue 3, Pages 388-399
出版商
Wiley
发表日期
2013-11-29
DOI
10.1111/jnc.12625
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Dravet syndrome patient-derived neurons suggest a novel epilepsy mechanism
- (2013) Yu Liu et al. ANNALS OF NEUROLOGY
- A Systematic Mammalian Genetic Interaction Map Reveals Pathways Underlying Ricin Susceptibility
- (2013) Michael C. Bassik et al. CELL
- Sustained Mobilization of Endogenous Neural Progenitors Delays Disease Progression in a Transgenic Model of Huntington’s Disease
- (2013) Abdellatif Benraiss et al. Cell Stem Cell
- Genetic Correction of a LRRK2 Mutation in Human iPSCs Links Parkinsonian Neurodegeneration to ERK-Dependent Changes in Gene Expression
- (2013) Peter Reinhardt et al. Cell Stem Cell
- Secreted Frizzled-Related Protein 3 Regulates Activity-Dependent Adult Hippocampal Neurogenesis
- (2013) Mi-Hyeon Jang et al. Cell Stem Cell
- Modeling Human Disease with Pluripotent Stem Cells: from Genome Association to Function
- (2013) Florian T. Merkle et al. Cell Stem Cell
- Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness
- (2013) Takayuki Kondo et al. Cell Stem Cell
- Modeling Dravet syndrome using induced pluripotent stem cells (iPSCs) and directly converted neurons
- (2013) Jiao Jiao et al. HUMAN MOLECULAR GENETICS
- Enhanced Aggregation of Androgen Receptor in Induced Pluripotent Stem Cell-derived Neurons from Spinal and Bulbar Muscular Atrophy
- (2013) Yoshihiro Nihei et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Directed differentiation of forebrain GABA interneurons from human pluripotent stem cells
- (2013) Yan Liu et al. Nature Protocols
- Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
- (2013) Yingsha Zhang et al. NEURON
- Deficits in human trisomy 21 iPSCs and neurons
- (2013) J. P. Weick et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Stepwise, non-adherent differentiation of human pluripotent stem cells to generate basal forebrain cholinergic neurons via hedgehog signaling
- (2013) Lucy A. Crompton et al. Stem Cell Research
- Patient-derived stem cells: pathways to drug discovery for brain diseases
- (2013) Alan Mackay-Sim Frontiers in Cellular Neuroscience
- A human Dravet syndrome model from patient induced pluripotent stem cells
- (2013) Norimichi Higurashi et al. Molecular Brain
- Induced Pluripotent Stem Cells from Patients with Huntington's Disease Show CAG-Repeat-Expansion-Associated Phenotypes
- (2012) The HD iPSC Consortium Cell Stem Cell
- Trisomy Correction in Down Syndrome Induced Pluripotent Stem Cells
- (2012) Li B. Li et al. Cell Stem Cell
- Genetic Correction of Huntington's Disease Phenotypes in Induced Pluripotent Stem Cells
- (2012) Mahru C. An et al. Cell Stem Cell
- Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease
- (2012) Adriana Sánchez-Danés et al. EMBO Molecular Medicine
- Evidence for premature aging due to oxidative stress in iPSCs from Cockayne syndrome
- (2012) Luciana Nogueira de Sousa Andrade et al. HUMAN MOLECULAR GENETICS
- Signaling defects in iPSC-derived fragile X premutation neurons
- (2012) Jing Liu et al. HUMAN MOLECULAR GENETICS
- Phosphatase and Tensin Homolog (PTEN)-induced Putative Kinase 1 (PINK1)-dependent Ubiquitination of Endogenous Parkin Attenuates Mitophagy
- (2012) Aleksandar Rakovic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis
- (2012) Rickie Patani et al. JOURNAL OF NEUROCHEMISTRY
- Genome-wide profiling of multiple histone methylations in olfactory cells: further implications for cellular susceptibility to oxidative stress in schizophrenia
- (2012) S Kano et al. MOLECULAR PSYCHIATRY
- Progressive degeneration of human neural stem cells caused by pathogenic LRRK2
- (2012) Guang-Hui Liu et al. NATURE
- The promise of induced pluripotent stem cells in research and therapy
- (2012) Daisy A. Robinton et al. NATURE
- Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression
- (2012) Gabsang Lee et al. NATURE BIOTECHNOLOGY
- CDKL5 ensures excitatory synapse stability by reinforcing NGL-1–PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons
- (2012) Sara Ricciardi et al. NATURE CELL BIOLOGY
- Induced pluripotent stem cells: the new patient?
- (2012) Milena Bellin et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity
- (2012) Stefano Camnasio et al. NEUROBIOLOGY OF DISEASE
- Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability
- (2012) B. Bilican et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells
- (2012) N. Egawa et al. Science Translational Medicine
- Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson's Disease
- (2012) O. Cooper et al. Science Translational Medicine
- Neuronal Properties, In Vivo Effects, and Pathology of a Huntington's Disease Patient-Derived Induced Pluripotent Stem Cells
- (2012) Iksoo Jeon et al. STEM CELLS
- Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells
- (2012) Houbo Jiang et al. Nature Communications
- Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington’s disease patient cells
- (2012) Tarja A Juopperi et al. Molecular Brain
- Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue
- (2012) Yoichi Imaizumi et al. Molecular Brain
- Induced pluripotent stem cell models from X-linked adrenoleukodystrophy patients
- (2011) Jiho Jang et al. ANNALS OF NEUROLOGY
- LRRK2 Mutant iPSC-Derived DA Neurons Demonstrate Increased Susceptibility to Oxidative Stress
- (2011) Ha Nam Nguyen et al. Cell Stem Cell
- Altered Oxygen Metabolism Associated to Neurogenesis of Induced Pluripotent Stem Cells Derived from a Schizophrenic Patient
- (2011) Bruna Da Silveira Paulsen et al. CELL TRANSPLANTATION
- Modeling familial Alzheimer's disease with induced pluripotent stem cells
- (2011) Takuya Yagi et al. HUMAN MOLECULAR GENETICS
- Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients
- (2011) Miguel Mitne-Neto et al. HUMAN MOLECULAR GENETICS
- Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation
- (2011) Aaron Y.L. Cheung et al. HUMAN MOLECULAR GENETICS
- Development of Patient-Specific Neurons in Schizophrenia Using Induced Pluripotent Stem Cells
- (2011) Erika Pedrosa et al. JOURNAL OF NEUROGENETICS
- Mitochondrial Parkin Recruitment Is Impaired in Neurons Derived from Mutant PINK1 Induced Pluripotent Stem Cells
- (2011) P. Seibler et al. JOURNAL OF NEUROSCIENCE
- Integration-free induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutation
- (2011) C-H Chiang et al. MOLECULAR PSYCHIATRY
- Modelling schizophrenia using human induced pluripotent stem cells
- (2011) Kristen J. Brennand et al. NATURE
- Direct generation of functional dopaminergic neurons from mouse and human fibroblasts
- (2011) Massimiliano Caiazzo et al. NATURE
- Increased Oxidative Damage and Decreased Antioxidant Function in Aging Human Substantia Nigra Compared to Striatum: Implications for Parkinson’s Disease
- (2011) C. Venkateshappa et al. NEUROCHEMICAL RESEARCH
- Isogenic Pairs of Wild Type and Mutant Induced Pluripotent Stem Cell (iPSC) Lines from Rett Syndrome Patients as In Vitro Disease Model
- (2011) Gene Ananiev et al. PLoS One
- Brief Report: Phenotypic Rescue of Induced Pluripotent Stem Cell-Derived Motoneurons of a Spinal Muscular Atrophy Patient
- (2011) Tammy Chang et al. STEM CELLS
- Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus
- (2011) Michael J. Devine et al. Nature Communications
- A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells
- (2010) Maria C.N. Marchetto et al. CELL
- Differential Modeling of Fragile X Syndrome by Human Embryonic Stem Cells and Induced Pluripotent Stem Cells
- (2010) Achia Urbach et al. Cell Stem Cell
- Efficient Derivation of Functional Floor Plate Tissue from Human Embryonic Stem Cells
- (2010) Christopher A. Fasano et al. Cell Stem Cell
- A Human iPSC Model of Hutchinson Gilford Progeria Reveals Vascular Smooth Muscle and Mesenchymal Stem Cell Defects
- (2010) Jinqiu Zhang et al. Cell Stem Cell
- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
- (2010) Noriyuki Matsuda et al. JOURNAL OF CELL BIOLOGY
- L1 retrotransposition in neurons is modulated by MeCP2
- (2010) Alysson R. Muotri et al. NATURE
- Direct conversion of fibroblasts to functional neurons by defined factors
- (2010) Thomas Vierbuchen et al. NATURE
- A TALE nuclease architecture for efficient genome editing
- (2010) Jeffrey C Miller et al. NATURE BIOTECHNOLOGY
- Peripheral Olfactory System for Clinical and Basic Psychiatry: A Promising Entry Point to the Mystery of Brain Mechanism and Biomarker Identification in Schizophrenia
- (2009) Akira Sawa et al. AMERICAN JOURNAL OF PSYCHIATRY
- Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins
- (2009) Hongyan Zhou et al. Cell Stem Cell
- Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
- (2009) Gabsang Lee et al. NATURE
- Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
- (2009) Stuart M Chambers et al. NATURE BIOTECHNOLOGY
- Disease-Specific Induced Pluripotent Stem Cells
- (2008) In-Hyun Park et al. CELL
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
- Induced pluripotent stem cells from a spinal muscular atrophy patient
- (2008) Allison D. Ebert et al. NATURE
- Highly efficient transient gene expression and gene targeting in primate embryonic stem cells with helper-dependent adenoviral vectors
- (2008) K. Suzuki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons
- (2008) J. T. Dimos et al. SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started