Clock gene variants in mood and anxiety disorders

A Survey of Genomic Studies Supports Association of Circadian Clock Genes with Bipolar Disorder Spectrum Illnesses and Lithium Response

(2012) Michael J. McCarthy et al.   PLoS One

Magnetically sensitive light-induced reactions in cryptochrome are consistent with its proposed role as a magnetoreceptor

(2012) K. Maeda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SIRT1 Activates MAO-A in the Brain to Mediate Anxiety and Exploratory Drive

(2011) Sergiy Libert et al.   CELL

Delay in Feedback Repression by Cryptochrome 1 Is Required for Circadian Clock Function

(2011) Maki Ukai-Tadenuma et al.   CELL

Crosstalk between Components of Circadian and Metabolic Cycles in Mammals

(2011) Gad Asher et al.   Cell Metabolism

TheCLOCKGene and Mood Disorders: A Case-Control Study and Meta-analysis

(2011) Taro Kishi et al.   CHRONOBIOLOGY INTERNATIONAL

When brain clocks lose track of time: cause or consequence of neuropsychiatric disorders

(2011) Jerome S Menet et al.   CURRENT OPINION IN NEUROBIOLOGY

Circadian clock gene Per3 variants influence the postpartum onset of bipolar disorder

(2011) S. Dallaspezia et al.   EUROPEAN PSYCHIATRY

Biochemical Analysis of the Canonical Model for the Mammalian Circadian Clock

(2011) Rui Ye et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Constant Darkness Induces IL-6-Dependent Depression-Like Behavior through the NF- B Signaling Pathway

(2011) F. J. Monje et al.   JOURNAL OF NEUROSCIENCE

A Global Circadian Repressor Controls Antiphasic Expression of Metabolic Genes in Neurospora

(2011) Gencer Sancar et al.   MOLECULAR CELL

Circadian rhythms persist without transcription in a eukaryote

(2011) John S. O’Neill et al.   NATURE

Circadian clocks in human red blood cells

(2011) John S. O’Neill et al.   NATURE

Circadian rhythms and depression: Human psychopathology and animal models

(2011) Noga Kronfeld-Schor et al.   NEUROPHARMACOLOGY

Reduced Light Response of Neuronal Firing Activity in the Suprachiasmatic Nucleus and Optic Nerve of Cryptochrome-Deficient Mice

(2011) Takahiro J. Nakamura et al.   PLoS One

Human cryptochrome exhibits light-dependent magnetosensitivity

(2011) Lauren E. Foley et al.   Nature Communications

Circadian Clock Gene Polymorphisms in Alcohol Use Disorders and Alcohol Consumption

(2010) L. Kovanen et al.   ALCOHOL AND ALCOHOLISM

Circadian clocks in mood-related behaviors

(2010) Urs Albrecht   ANNALS OF MEDICINE

An Association Analysis of Circadian Genes in Anxiety Disorders

(2010) Tessa Sipilä et al.   BIOLOGICAL PSYCHIATRY

Association of Per3 gene with bipolar disorder: comment on “Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia”

(2010) Paulo Marcos Brasil Rocha et al.   BIPOLAR DISORDERS

T3111C CLOCK SINGLE NUCLEOTIDE POLYMORPHISM AND MOOD DISORDERS: A META-ANALYSIS

(2010) Raffaella Calati et al.   CHRONOBIOLOGY INTERNATIONAL

3111T/C CLOCKGENE POLYMORPHISM IS NOT ASSOCIATED WITH SLEEP DISTURBANCES IN UNTREATED DEPRESSED PATIENTS

(2010) Alessandro Serretti et al.   CHRONOBIOLOGY INTERNATIONAL

Circadian Clock Gene Bmal1 Is Not Essential; Functional Replacement with its Paralog, Bmal2

(2010) Shuqun Shi et al.   CURRENT BIOLOGY

Ligand regulation of retinoic acid receptor-related orphan receptors: implications for development of novel therapeutics

(2010) Laura A Solt et al.   CURRENT OPINION IN LIPIDOLOGY

The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors

(2010) I. Schmutz et al.   GENES & DEVELOPMENT

Genetic variants and abnormal processing of pre-miR-182, a circadian clock modulator, in major depression patients with late insomnia

(2010) Ester Saus et al.   HUMAN MOLECULAR GENETICS

SIRT1 gene is associated with major depressive disorder in the Japanese population

(2010) Taro Kishi et al.   JOURNAL OF AFFECTIVE DISORDERS

Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder

(2010) Y Liu et al.   MOLECULAR PSYCHIATRY

Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

(2010) Eric E Zhang et al.   NATURE MEDICINE

Differential Association of Circadian Genes with Mood Disorders: CRY1 and NPAS2 are Associated with Unipolar Major Depression and CLOCK and VIP with Bipolar Disorder

(2010) Virginia Soria et al.   NEUROPSYCHOPHARMACOLOGY

CRY2 Is Associated with Depression

(2010) Catharina Lavebratt et al.   PLoS One

Systematic Analysis of Circadian Genes in a Population-Based Sample Reveals Association of TIMELESS with Depression and Sleep Disturbance

(2010) Siddheshwar J. Utge et al.   PLoS One

CRY2 Is Associated with Rapid Cycling in Bipolar Disorder Patients

(2010) Louise K. Sjöholm et al.   PLoS One

Association between CLOCK 3111T/C and preferred circadian phase in Korean patients with bipolar disorder

(2010) Kyu Young Lee et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The clock gene PER2 and sleep problems: Association with alcohol consumption among Swedish adolescents

(2010) Erika Comasco et al.   UPSALA JOURNAL OF MEDICAL SCIENCES

PER2 variantion is associated with depression vulnerability

(2009) Catharina Lavebratt et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Association study in a Sardinian sample between bipolar disorder and the nuclear receptorREV-ERBαgene, a critical component of the circadian clock system

(2009) Giovanni Severino et al.   BIPOLAR DISORDERS

Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia

(2009) Hader A Mansour et al.   BIPOLAR DISORDERS

Evidence for genetic association of RORB with bipolar disorder

(2009) Casey L McGrath et al.   BMC Psychiatry

Association study of clock gene (CLOCK) and schizophrenia and mood disorders in the Japanese population

(2009) Taro Kishi et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Preferential Inhibition of BMAL2-CLOCK Activity by PER2 Reemphasizes Its Negative Role and a Positive Role of BMAL2 in the Circadian Transcription

(2009) Momoko Sasaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rhythmic PER Abundance Defines a Critical Nodal Point for Negative Feedback within the Circadian Clock Mechanism

(2009) Rongmin Chen et al.   MOLECULAR CELL

Daily Electrical Silencing in the Mammalian Circadian Clock

(2009) M. D. C. Belle et al.   SCIENCE

Harmonics of Circadian Gene Transcription in Mammals

(2009) Michael E. Hughes et al.   PLoS Genetics

Clock genes may influence bipolar disorder susceptibility and dysfunctional circadian rhythm

(2008) Jiajun Shi et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Convergent functional genomics of genome-wide association data for bipolar disorder: Comprehensive identification of candidate genes, pathways and mechanisms

(2008) H. Le-Niculescu et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Regulation of Monoamine Oxidase A by Circadian-Clock Components Implies Clock Influence on Mood

(2008) Gabriele Hampp et al.   CURRENT BIOLOGY

The circadian basis of mood disorders: Recent developments and treatment implications

(2008) Palmiero Monteleone et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Proof-by-synthesis of the transcriptional logic of mammalian circadian clocks

(2008) Maki Ukai-Tadenuma et al.   NATURE CELL BIOLOGY

The genetics of mammalian circadian order and disorder: implications for physiology and disease

(2008) Joseph S. Takahashi et al.   NATURE REVIEWS GENETICS

A length polymorphism in the circadian clock gene Per3 influences age at onset of bipolar disorder

(2008) Francesco Benedetti et al.   NEUROSCIENCE LETTERS

Association analysis of nuclear receptor Rev-erb alpha gene (NR1D1) with mood disorders in the Japanese population

(2008) Taro Kishi et al.   NEUROSCIENCE RESEARCH

Light deprivation damages monoamine neurons and produces a depressive behavioral phenotype in rats

(2008) M. M. C. Gonzalez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

cAMP-Dependent Signaling as a Core Component of the Mammalian Circadian Pacemaker

(2008) J. S. O'Neill et al.   SCIENCE

When Clocks Go Bad: Neurobehavioural Consequences of Disrupted Circadian Timing

(2008) Alun R. Barnard et al.   PLoS Genetics

Association between GSK-3β -50T/C polymorphism and personality and psychotic symptoms in mood disorders

(2007) Alessandro Serretti et al.   PSYCHIATRY RESEARCH