Gold nanoparticles trigger apoptosis and necrosis in lung cancer cells with low intracellular glutathione

Trans-10, cis-12 conjugated linoleic acid induced cell death in human colon cancer cells through reactive oxygen species-mediated ER stress

(2013) Anne-Sophie Pierre et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

p53 signalling controls cell cycle arrest and caspase-independent apoptosis in macrophages infected with pathogenicLeptospiraspecies

(2013) Weilin Hu et al.   CELLULAR MICROBIOLOGY

Membrane Localized Iridium(III) Complex Induces Endoplasmic Reticulum Stress and Mitochondria-Mediated Apoptosis in Human Cancer Cells

(2013) Rui Cao et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Blocking of c-Met Signaling Induces Apoptosis through the Increase of p53 Protein in Lung Cancer

(2013) Hae-Yun Jung et al.   Cancer Research and Treatment

Nanotheranostics for personalized medicine

(2012) Simona Mura et al.   ADVANCED DRUG DELIVERY REVIEWS

Molecular mechanisms of garlic-derived allyl sulfides in the inhibition of skin cancer progression

(2012) Hsiao-Chi Wang et al.   Annals of the New York Academy of Sciences

UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and autophagic cell death in pancreatic adenocarcinoma cells

(2012) Ilaria Dando et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production

(2012) G. B. Fortes et al.   BLOOD

PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress

(2012) T Verfaillie et al.   CELL DEATH AND DIFFERENTIATION

Chrysophanol-induced cell death (necrosis) in human lung cancer A549 cells is mediated through increasing reactive oxygen species and decreasing the level of mitochondrial membrane potential

(2012) Chien-Hang Ni et al.   ENVIRONMENTAL TOXICOLOGY

Denbinobin induces human glioblastoma multiforme cell apoptosis through the IKKα–Akt–FKHR signaling cascade

(2012) Hsing-Yu Weng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Coxiella burnetii Induces Apoptosis during Early Stage Infection via a Caspase-Independent Pathway in Human Monocytic THP-1 Cells

(2012) Yan Zhang et al.   PLoS One

Berberine Induces Caspase-Independent Cell Death in Colon Tumor Cells through Activation of Apoptosis-Inducing Factor

(2012) Lihong Wang et al.   PLoS One

Laminin receptor specific therapeutic gold nanoparticles (198AuNP-EGCg) show efficacy in treating prostate cancer

(2012) R. Shukla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small Molecule-Gold Nanorod Conjugates Selectively Target and Induce Macrophage Cytotoxicity towards Breast Cancer Cells

(2012) Erik C. Dreaden et al.   Small

Ccdc94 Protects Cells from Ionizing Radiation by Inhibiting the Expression of p53

(2012) Shelly Sorrells et al.   PLoS Genetics

Monodisperse Magnetic Nanoparticles for Theranostic Applications

(2011) Don Ho et al.   ACCOUNTS OF CHEMICAL RESEARCH

Gold Nanocages: From Synthesis to Theranostic Applications

(2011) Younan Xia et al.   ACCOUNTS OF CHEMICAL RESEARCH

Functionalization of Inorganic Nanoparticles for Bioimaging Applications

(2011) Nandanan Erathodiyil et al.   ACCOUNTS OF CHEMICAL RESEARCH

Mechanized Silica Nanoparticles: A New Frontier in Theranostic Nanomedicine

(2011) Michael W. Ambrogio et al.   ACCOUNTS OF CHEMICAL RESEARCH

Mitochondrial outer membrane permeabilization during apoptosis: The role of mitochondrial fission

(2011) Thomas Landes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Targeting the mitochondrial pathway to induce apoptosis/necrosis through ROS by a newly developed Schiff’s base to overcome MDR in cancer

(2011) Soumya Basu et al.   BIOCHIMIE

Proteomic characterization of differentially expressed proteins associated with no stress in retinal ganglion cells

(2011) Jum-Ji Kim et al.   BMB Reports

Targeting the extrinsic apoptosis signaling pathway for cancer therapy

(2011) Thomas J. Sayers   CANCER IMMUNOLOGY IMMUNOTHERAPY

Chemotherapeutic Properties of Phospho-Nonsteroidal Anti-Inflammatory Drugs, a New Class of Anticancer Compounds

(2011) L. Huang et al.   CANCER RESEARCH

Measuring and Modeling Apoptosis in Single Cells

(2011) Sabrina L. Spencer et al.   CELL

Mitochondrial permeability transition in Ca2+-dependent apoptosis and necrosis

(2011) Andrea Rasola et al.   CELL CALCIUM

Association of Glutathione Level and Cytotoxicity of Gold Nanoparticles in Lung Cancer Cells

(2011) Yunxue Zhao et al.   Journal of Physical Chemistry C

Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death

(2011) Domagoj Vucic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Withaferin A-Induced Apoptosis in Human Breast Cancer Cells Is Mediated by Reactive Oxygen Species

(2011) Eun-Ryeong Hahm et al.   PLoS One

Fate and Toxicity of Metallic and Metal-Containing Nanoparticles for Biomedical Applications

(2011) Yu-Feng Li et al.   Small

Water-soluble germanium nanoparticles cause necrotic cell death and the damage can be attenuated by blocking the transduction of necrotic signaling pathway

(2011) Yu-Hsin Ma et al.   TOXICOLOGY LETTERS

A Drug-Loaded Aptamer−Gold Nanoparticle Bioconjugate for Combined CT Imaging and Therapy of Prostate Cancer

(2010) Dongkyu Kim et al.   ACS Nano

Hydrophilic Co@Au Yolk/Shell Nanospheres: Synthesis, Assembly, and Application to Gene Delivery

(2010) Yang Lu et al.   ADVANCED MATERIALS

Mitochondrial regulation of cell death: Processing of apoptosis-inducing factor (AIF)

(2010) Erik Norberg et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Calcium uptake mechanisms of mitochondria

(2010) Jaime Santo-Domingo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Low Molecular Weight Polyethylenimine Conjugated Gold Nanoparticles as Efficient Gene Vectors

(2010) Chu Hu et al.   BIOCONJUGATE CHEMISTRY

N-(8-(3-Ethynylphenoxy)octyl-1-deoxynojirimycin suppresses growth and migration of human lung cancer cells

(2010) Yunxue Zhao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Biodistribution and toxicity of engineered gold nanoparticles: a review of in vitro and in vivo studies

(2010) Nikolai Khlebtsov et al.   CHEMICAL SOCIETY REVIEWS

hsBAFF regulates proliferation and response in cultured CD4+ T lymphocytes by upregulation of intracellular free Ca2+ homeostasis

(2010) Ling Wen et al.   CYTOKINE

Toxicity and cellular uptake of gold nanoparticles: what we have learned so far?

(2010) Alaaldin M. Alkilany et al.   JOURNAL OF NANOPARTICLE RESEARCH

Nuclear Targeting of Gold Nanoparticles in Cancer Cells Induces DNA Damage, Causing Cytokinesis Arrest and Apoptosis

(2010) Bin Kang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reactive oxygen species in TNFα-induced signaling and cell death

(2010) Michael J. Morgan et al.   MOLECULES AND CELLS

Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis

(2010) G. Trichonas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineering Nanocomposite Materials for Cancer Therapy

(2010) Caterina Minelli et al.   Small

Protection against reactive oxygen species by selenoproteins

(2009) Holger Steinbrenner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

BH3-only proteins Mcl-1 and Bim as well as endonuclease G are targeted in spongistatin 1-induced apoptosis in breast cancer cells

(2009) U. M. Schneiders et al.   MOLECULAR CANCER THERAPEUTICS

HYD1-induced increase in reactive oxygen species leads to autophagy and necrotic cell death in multiple myeloma cells

(2009) R. R. Nair et al.   MOLECULAR CANCER THERAPEUTICS

RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

(2009) D.-W. Zhang et al.   SCIENCE

Gold Nanoparticles of Diameter 1.4 nm Trigger Necrosis by Oxidative Stress and Mitochondrial Damage

(2009) Yu Pan et al.   Small

A role for actin in regulating apoptosis/programmed cell death: evidence spanning yeast, plants and animals

(2008) Vernonica E. Franklin-Tong et al.   BIOCHEMICAL JOURNAL

Rho/ROCK/actin signaling regulates membrane androgen receptor induced apoptosis in prostate cancer cells

(2008) N PAPADOPOULOU et al.   EXPERIMENTAL CELL RESEARCH

Apoptosis-associated caspase activation assays

(2008) Scott H. Kaufmann et al.   METHODS

Apoptosis and necrosis: Detection, discrimination and phagocytosis

(2008) Dmitri V. Krysko et al.   METHODS

Bypassing cancer drug resistance by activating multiple death pathways – A proposal from the study of circumventing cancer drug resistance by induction of necroptosis

(2007) Xun Hu et al.   CANCER LETTERS