CES1 genetic variation affects the activation of angiotensin-converting enzyme inhibitors

The effects of CES1A2 A(−816)C and CYP2C19 loss-of-function polymorphisms on clopidogrel response variability among Chinese patients with coronary heart disease

(2014) Cheng Xie et al.   Pharmacogenetics and Genomics

CES1A −816C as a Genetic Marker to Predict Greater Platelet Clopidogrel Response in Patients with Percutaneous Coronary Intervention

(2013) Jian-Jun Zou et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Pharmacogenetics of ACE inhibitor-induced angioedema and cough: a systematic review and meta-analysis

(2013) Seyed Hamidreza Mahmoudpour et al.   PHARMACOGENOMICS

A rapid and sensitive liquid chromatography-tandem mass spectrometric assay for moexipril, an angiotensin-converting enzyme inhibitor in human plasma

(2012) Vijaya Kumari Karra et al.   BIOMEDICAL CHROMATOGRAPHY

Carboxylesterase 1 Polymorphism Impairs Oseltamivir Bioactivation in Humans

(2012) E K Tarkiainen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The effect of carboxylesterase 1 (CES1) polymorphisms on the pharmacokinetics of oseltamivir in humans

(2012) Yuki Suzaki et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response

(2012) Joshua P. Lewis et al.   Pharmacogenetics and Genomics

Association of a carboxylesterase 1 polymorphism with appetite reduction in children and adolescents with attention-deficit/hyperactivity disorder treated with methylphenidate

(2012) E M Bruxel et al.   PHARMACOGENOMICS JOURNAL

Dose-Dependent Antihypertensive Efficacy and Tolerability of Perindopril in a Large, Observational, 12-Week, General Practice-Based Study

(2011) George Tsoukas et al.   American Journal of Cardiovascular Drugs

Organ-specific carboxylesterase profiling identifies the small intestine and kidney as major contributors of activation of the anticancer prodrug CPT-11

(2010) M. Jason Hatfield et al.   BIOCHEMICAL PHARMACOLOGY

Association of carboxylesterase 1A genotypes with irinotecan pharmacokinetics in Japanese cancer patients

(2010) Kimie Sai et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Homology modeling and metabolism prediction of human carboxylesterase-2 using docking analyses by GriDock: a parallelized tool based on AutoDock 4.0

(2010) Giulio Vistoli et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Antihypertensive efficacy and safety of olmesartan medoxomil and ramipril in elderly patients with mild to moderate essential hypertension: the ESPORT study

(2010) Ettore Malacco et al.   JOURNAL OF HYPERTENSION

Effects of antihypertensive-drug class on interindividual variation in blood pressure and risk of stroke: a systematic review and meta-analysis

(2010) Alastair JS Webb et al.   LANCET

Genetic variation in carboxylesterase genes and susceptibility to isoniazid-induced hepatotoxicity

(2010) S Yamada et al.   PHARMACOGENOMICS JOURNAL

Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril

(2009) Hao-Jie Zhu et al.   BIOCHEMICAL PHARMACOLOGY

Antihypertensive Efficacy of Perindopril 5–10 mg/day in Primary Health Care

(2009) Dan-Dominic Ionescu   CLINICAL DRUG INVESTIGATION

Carboxylesterase 1 gene polymorphism and methylphenidate response in ADHD

(2009) Zsofia Nemoda et al.   NEUROPHARMACOLOGY

Two CES1 Gene Mutations Lead to Dysfunctional Carboxylesterase 1 Activity in Man: Clinical Significance and Molecular Basis

(2008) Hao-Jie Zhu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Human carboxylesterases HCE1 and HCE2: Ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin

(2008) Dongfang Yang et al.   BIOCHEMICAL PHARMACOLOGY

Simultaneous Determination of Ramipril and Its Active Metabolite Ramiprilat in Human Plasma by LC–MS–MS

(2008) Bo Yuan et al.   CHROMATOGRAPHIA

Activation of the Antiviral Prodrug Oseltamivir Is Impaired by Two Newly Identified Carboxylesterase 1 Variants

(2008) H.-J. Zhu et al.   DRUG METABOLISM AND DISPOSITION

Structure and Catalytic Properties of Carboxylesterase Isozymes Involved in Metabolic Activation of Prodrugs

(2008) Masakiyo Hosokawa   MOLECULES

Structure and characterization of human carboxylesterase 1A1, 1A2, and 1A3 genes

(2008) Tatsuki Fukami et al.   Pharmacogenetics and Genomics