Article
Chemistry, Physical
Budhadeb Chowdhury, Sk Mehebub Rahaman, Aniruddha Ghosh, Kalachand Mahali, Pintu Sar, Bidyut Saha
Summary: This study investigates the employment of two surfactants in the oxidation of 1-propanol and 1,3-propanediol by copper(III)-periodate (DPC) complex in aqueous micellar media. The results show a significant enhancement in the catalytic efficiency of the oxidation reactions when both surfactants are present in equimolar amounts. Additionally, the aggregation of the binary surfactants plays a crucial role in the analysis of the absolute kinetic results of the oxidation study.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Inorganic & Nuclear
Tian Ma, Xiang Ma, Zhengguo Lin, Jiayao Zhang, Peng Yang, Tibor Csupasz, Imre Toth, Sonja Misirlic-Dencic, Andjelka M. Isakovic, David Lembo, Manuela Donalisio, Ulrich Kortz
Summary: Phosphate-capped 12-palladate nanocubes and 23-palladate double-cube have been synthesized and characterized. They exhibit antitumor and antiviral activities against human melanoma and acute promyelocytic leukemia cells, as well as inhibitory activity against herpes simplex virus in a dose-dependent manner.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Physical
M. K. Thriveni, I Mallikarjuna, S. Bellappa, T. Shivalingaswamy
Summary: The study found that factors such as ionic strength, resulting products, and dielectric constant affect the performance of caffeine in oxidation reactions, and activation parameters were also evaluated.
RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY A
(2021)
Article
Engineering, Environmental
Sanzeeda Baig Shuchi, Md. Burhan Kabir Suhan, Sufian Bin Humayun, Muhammad Enamul Haque, Md. Shahinoor Islam
Summary: The study demonstrates that heat-activated persulfate is a promising method for efficiently degrading water-soluble dyes in textile wastewater. By adjusting temperature, time, and persulfate concentration, removal rates of the dye can be enhanced. Kinetic study reveals that the degradation of the dye follows a first-order model.
JOURNAL OF WATER PROCESS ENGINEERING
(2021)
Review
Environmental Sciences
Jialiang Liang, Xinmiao Huang, Jingwen Yan, Yunyi Li, Zhiwei Zhao, Yuanyuan Liu, Jiangyu Ye, Yunmei Wei
Summary: This review discusses the process of Cr(III) oxidation generating Cr(VI) in soils and groundwater, with manganese oxides, hydrogen peroxide, and photochemical generated radicals playing dominant roles under different conditions.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Biotechnology & Applied Microbiology
Banda Yeny, Texier Anne-Claire, Cuervo-Lopez Flor de Maria
Summary: The study showed that denitrification can be conducted using AMP as an electron donor, but at lower specific rates. At high concentrations of AMP, the production of N2O and carbon intermediates was detected.
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
(2022)
Article
Environmental Sciences
Yusuf Azmi Akbas, Sabriye Yusan, Senol Sert, Sule Aytas
Summary: In this study, magnetite and magnetic olive pomace nanocomposite were prepared by a partial reduction co-precipitation method for the removal of Ce3+ ions from aqueous solution. Various parameters affecting sorption efficiency were investigated, showing high sorption capacities for Ce(III) ions. These materials were found to be effective and sustainable adsorbents for cerium ion removal.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Chemistry, Multidisciplinary
Carla J. Spina, Johanny E. Notarandrea-Alfonzo, Elizabeth D. Guerra, Carlie Goodall, D. Scott Bohle, Rod Precht
Summary: This study successfully synthesized a stable silver complex containing Ag(III) through chemical oxidation and chelation, achieving high yield and purity. The structure offers stability under both long-term and thermal conditions, with thermal analysis revealing a solid-state reduction reaction from Ag(III) to Ag(I). No significant degradation was observed over a 12 month period in a solid state, with a half-life of 147 days in a pH-neutral aqueous solution.
Article
Electrochemistry
L. Volpe, M. Curioni, M. G. Burke, F. Scenini
Summary: This paper focuses on establishing a thermodynamic equivalence between laboratory systems like low pressure superheated hydrogenated steam and supercritical hydrogenated water, and the PWR primary water environments. By utilizing experimental data and relationships, the applicability of correlations for selecting experimental conditions and equivalence charts are demonstrated and discussed.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2021)
Article
Environmental Sciences
Tengfei Zhang, Lihu Liu, Wenfeng Tan, Steven L. Suib, Guohong Qiu
Summary: This study reveals the important role of Mn(III) intermediates in the formation of natural Mn oxide minerals. The rate of oxidation of Mn2+ to Mn(IV) oxide minerals decreases with increasing initial Mn2+ concentration, while the increase in NO3- concentration, pH, and temperature promotes Mn2+ photochemical oxidation. Additionally, at low ligand concentrations, the photochemical formation rate of Mn(IV) oxide minerals increases with increasing ligand concentrations.
Article
Multidisciplinary Sciences
Vitus Besel, Milica Todorovic, Theo Kurten, Patrick Rinke, Hanna Vehkamaki
Summary: In this study, the GeckoQ dataset was created, which includes atomic structures of 31,637 atmospherically relevant molecules. This dataset can accelerate the research on key atmospheric processes driven by low-volatile organic compounds (LVOCs), such as new particle formation and growth. Machine learning tools were used to explore the relationship between structural and thermodynamic properties, and a first application of Gaussian process regression was demonstrated.
Review
Chemistry, Inorganic & Nuclear
Rocio Uzal-Varela, Aurora Rodriguez-Rodriguez, Huan Wang, David Esteban-Gomez, Isabel Brandariz, Eric M. Gale, Peter Caravan, Carlos Platas-Iglesias
Summary: This research developed a method for predicting Gd(III)-ligand formation constant and pGd at pH 7.4 using known stability constants and structural descriptors, showing strong predictive power and potential for screening potential ligands.
COORDINATION CHEMISTRY REVIEWS
(2022)
Article
Biochemistry & Molecular Biology
Jhon K. A. Pereira, Andre G. C. Costa, Edson S. B. Rodrigues, Isaac Y. L. Macedo, Marx O. A. Pereira, Ricardo Menegatti, Severino C. B. de Oliveira, Freddy Guimaraes, Luciano M. Liao, Jose R. Sabino, Eric de S. Gil
Summary: This study investigates the potential of a novel analogue of trimetozine antioxidant using electrochemical and DFT calculation approaches. The electrochemical behavior and electronic structure of the compound, LQFM289, were examined, revealing its potential as a therapeutic agent with good redox properties.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Materials Science, Ceramics
C. Chatillon, F. Teyssandier
Summary: This article reviews and analyzes the oxidation studies of SiC, focusing on the high temperature behavior of SiC material and its relationship with gas flows. By studying the chemical surface and interface mechanisms involved in active and passive oxidation, as well as the transitions between active and passive processes, the experimental data is discussed in relation to thermodynamic equilibrium processes.
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
(2022)
Article
Chemistry, Physical
Zachary J. Schiffer, Aditya M. Limaye, Karthish Manthiram
Summary: This work introduces a reaction-independent expression for the equilibrium constant, allowing for a clear visual divide between electrochemically and thermochemically driven reactions and providing a physical basis for energy analysis.
Article
Chemistry, Physical
Keerthi Prabhu, Shweta J. Malode, Nagaraj P. Shetti
Summary: In this study, the electrochemical performance of carbendazim (CBM) was analyzed. It was found that Vat Violet 2R (VVR) dye-modified glassy carbon electrode (GCE) can enhance the peak current of CBM and exhibit excellent electrocatalytic behavior.
Review
Engineering, Environmental
Anushka Garg, Nagaraj P. Shetti, Soumen Basu, Mallikarjuna N. Nadagouda, Tejraj M. Aminabhavi
Summary: PFAS possess unique characteristics, making them resistant to degradation and leading to limitations in the development of new technologies. This review provides insights into various PFAS destruction technologies, their classifications, exposure scenarios, detection methods, and the mechanism of PFAS degradation during thermal processes.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Energy & Fuels
Manuraj Mohan, Nagaraj P. Shetti, Tejraj M. Aminabhavi
Summary: Among transition metal chalcogenides, MoS2 is widely studied due to its fascinating physico-chemical properties. Its layered structure and high surface-to-volume ratio have attracted attention in energy storage, leading to numerous applications. While there are review articles on MoS2 and MoS2-based nanocomposites for energy storage applications, there is a lack of reviews focusing on the supercapacitor performance of MoS2. This article presents recent advances in MoS2-based supercapacitors, discussing the conducting-semiconducting phases, doping effects, and the status of MoS2 in flexible and wearable supercapacitors, as well as future prospects and challenges as electrode materials.
JOURNAL OF ENERGY STORAGE
(2023)
Article
Chemistry, Multidisciplinary
Manuraj Mohan, Nagaraj P. Shetti, Tejraj M. Aminabhavi
Summary: Miniaturization of electronic devices is increasingly common in the modern world. Development of flexible energy storage devices, particularly flexible supercapacitors using MoS2, has gained attention due to their superior performance and potential applications in various technologies. This review discusses recent applications, scope, and the development of MoS2-based flexible supercapacitors in composite forms with other materials, as well as self-standing devices that can generate and store energy.
MATERIALS TODAY CHEMISTRY
(2023)
Article
Environmental Sciences
Ch. Venkata Reddy, Aashna Nagar, Nagaraj P. Shetti, I. Neelakanta Reddy, Soumen Basu, Jaesool Shim, Raghava Reddy Kakarla
Summary: In this study, novel g-C3N4/BiVO4 nanohybrid catalysts were prepared and characterized. The composite catalyst exhibited enhanced photocatalytic degradation efficiency of methylene blue and tetracycline pollutants.
Review
Environmental Sciences
Rajesh K. Srivastava, Nagaraj P. Shetti, Kakarla Raghava Reddy, Mallikarjuna N. Nadagouda, Michael Badawi, Adrian Bonilla-Petriciolet, Tejraj M. Aminabhavi
Summary: The review discusses the importance of proper management and disposal of biowastes generated from natural resources and anthropogenic activities. It highlights the potential of using these biomaterials as low-cost raw feedstock to produce bioenergy and value-added products. Various technologies for the transformation and valorization of biowastes are analyzed, along with their applications in water pollution, soil fertility, and green energy generation.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
Article
Biophysics
B. R. Karishma, G. Manasa, Arvind K. Bhakta, T. Maiyalagan, Ronald J. Mascarenhas, Nagaraj P. Shetti
Summary: P.HCl is an early and commonly used local anesthetic drug, but excessive administration can lead to systemic toxicity. Therefore, it is crucial to develop a sensor for real-time monitoring and quality control of the drug during its industrial preparations. In this study, a simple yet highly selective and sensitive sensor based on BaO-MWCNT/CPE was fabricated for P.HCl detection.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Energy & Fuels
Ranjan S. Shetti, Madasu Sreenivasulu, Selvam Mathi, Nagaraj P. Shetti
Summary: Developing low-cost, easily synthesizable, and incredibly efficient electrocatalysts is crucial for transitioning to hydrogen fuel generation. The Cu@FeCN catalyst shows sustained stability and strong catalytic activity, making it a promising candidate for water electrolysis.
Review
Energy & Fuels
Nagaraj P. P. Shetti, Amit Mishra, Soumen Basu, Tejraj M. M. Aminabhavi, Abdullah Alodhayb, Saravanan Pandiaraj
Summary: MXenes have attracted significant attention as outstanding materials for energy storage applications due to their extraordinary properties such as layered structure, metal-like high thermal stability, good mechanical strength, high conductivity, presence of active sites, and terminal functional groups. However, their performance in Li-ion batteries is not satisfactory compared to the state-of-the-art electrodes. Attempts have been made to modify their surfaces and/or surface terminal groups, as well as synthesize MXene-based composites, to improve their performance. This review focuses on MXene-based electrode materials for applications in Li-ion batteries.
Article
Environmental Sciences
Keerthi Prabhu, Shweta J. Malode, Nagaraj P. Shetti, Saravanan Pandiaraj, Abdullah Alodhayb, Muthumareeswaran Muthuramamoorthy
Summary: This research presents the development of an electroanalytical sensor for detecting 2-phenylphenol (2PPL) as a contaminant, utilizing a 1-D nanostructured WO3/CuO nanocomposite integrated with a carbon paste electrode (CPE). The WO3 NPs were synthesized using the hydrothermal method and characterized using scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS) techniques. The electroanalytical sensor showed outstanding catalytic behavior by enhancing the peak current of 2-phenylphenol with a potential shift to the less positive side.
ENVIRONMENTAL RESEARCH
(2023)
Review
Environmental Sciences
G. Velvizhi, P. Jennita Jacqueline, Nagaraj P. Shetti, K. Latha, Gunda Mohanakrishna, Tejraj M. Aminabhavi
Summary: Sustainable technologies convert lignocellulosic biomass into fuels, carbon-neutral materials, and chemicals, which can potentially replace fossil fuels to meet future energy demand. This review explores advanced thermochemical processes such as plasma technology, hydrothermal treatment, microwave-based processing, microbial-catalyzed electrochemical systems, as well as advanced biochemical technologies such as synthetic metabolic engineering and genomic engineering, which enhance biofuel production efficiency. Microwave-plasma-based technique increases biofuel conversion efficiency by 97%, and genetic engineering strains increase sugar production by 40%, indicating the effectiveness of advanced technologies. Understanding these processes is crucial for developing low-carbon technologies to address global energy security, greenhouse gas emissions, and global warming.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
Review
Chemistry, Physical
Manuraj Mohan, Nagaraj P. Shetti, Tejraj M. Aminabhavi
Summary: In recent decades, perovskite structures have gained significant attention in various electronics applications. The controllable physico-chemical properties and structural advantages of perovskites have been extensively explored for energy storage applications. This review discusses the recent applications and potential of perovskite structures in supercapacitors using oxide, fluoride, and halide perovskite materials. It provides details on different perovskite structures, such as single and double perovskites, and strategies for improving the electrochemical performance through composite structures, elemental doping, morphology tuning, crystallinity, and surface defect engineering to enhance oxygen vacancies.
JOURNAL OF POWER SOURCES
(2023)
Article
Chemistry, Analytical
G. Manasa, Arvind K. Bhakta, Ronald J. Mascarenhas, Nagaraj P. Shetti
Summary: Population growth has led to industrialization and intensive agricultural methods, resulting in deterioration of water quality due to contamination by hazardous pesticides. The herbicide Diuron (DIU) has been studied as a priority pollutant. The BaO-MWCNT composite material was used to modify the working electrode surface, increasing the efficiency of the Faradaic reaction and enhancing the electrochemical surface area. The developed sensor showed good selectivity, sensitivity, and reliability for DIU determinations.
MICROCHEMICAL JOURNAL
(2023)
Review
Nanoscience & Nanotechnology
Neeraj Sohal, Sonali Singla, Shweta J. J. Malode, Soumen Basu, Banibrata Maity, Nagaraj P. P. Shetti
Summary: The increasing demand for facile, cheap, and green approaches for creating emerging materials from bioresources has led to the development of graphene quantum dots (GQDs). Biomass-derived GQDs have gained attention due to their green, inexpensive, and environmental-friendly nature. This review discusses the challenges and methodologies of converting bioprecursors into ecofriendly GQDs, and explores their attractive properties such as large surface area, low toxicity, and good biocompatibility. It also highlights the potential applications of biomass-derived GQDs in the biomedical field and energy applications, as well as future research directions.
ACS APPLIED NANO MATERIALS
(2023)
Article
Engineering, Environmental
Mahesh M. Shanbhag, G. Manasa, Ronald J. Mascarenhas, Kunal Mondal, Nagaraj P. Shetti
Summary: Biosensors derive their name from the utilization of bio-functionalities such as biorecognition or catalysis. Bioelectrochemical sensing is a new discipline that combines biological detection and electrochemical transduction. Bioelectrochemical sensors are devices that use biological materials as receptors to detect target analytes in various samples, converting biological interactions into electrical impulses for study. These sensors have demonstrated promise in clinical diagnostics, environmental monitoring, food safety, and biotechnology due to their speed, simplicity, and cost-effectiveness. This article covers the principles, design strategies, techniques, advantages, and applications of bioelectrochemical sensors, along with the rationale for developing electrochemical biosensors.
CHEMICAL ENGINEERING JOURNAL ADVANCES
(2023)
Article
Chemistry, Physical
Xinlei Chen, Shiyi Chen, Xuele Lin, Jingxuan Zhou, Xingjun Gao, Yaoqi Zhen, Xiaodan Ma, Shouwen Jin, Linfang Shi, Hui Liu, Daqi Wang
Summary: Nine mixed-ligand Cd2+ complexes with different geometric structures were synthesized and characterized. The complexes exhibit various coordination modes and form both intra- and intermolecular hydrogen bonds.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Rupali Mahajan, Abhishek Sharma, Bhagyashree Patra, Lijo Mani, Parul Grover, Sandeep Kumar, Santosh Kumar Guru, Gananadhamu Samanthula, Amol G. Dikundwar, Amit Asthana
Summary: This research article provides a comprehensive characterization and toxicological assessment of a photoisomeric impurity of the antianemic drug Roxadustat. The impurity has a distinct structure compared to the drug and its formation due to light exposure is a concern. Through various experiments, including single crystal XRD, physicochemical characterization, and in vitro cytotoxicity assays, the researchers confirmed the structure of the impurity, evaluated its conversion with Roxadustat, and assessed its toxicological activity. These findings contribute to the understanding of drug stability, safety, and formulation development.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Laila S. Alqarni, Azzah M. Alghamdi, Nuha Y. Elamin, A. Rajeh
Summary: The solution casting method was used to produce a new type of nanocomposites made of chitosan, gelatin, and co-doped ZnO nanoparticles. The addition of 3.5% co-doped ZnO nanoparticles improved the physicochemical characteristics and antimicrobial effects of the nanocomposites, indicating their significant potential in food packaging and energy storage.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Ruchi Gaur
Summary: The structure and intermolecular interactions of a newly synthesized bis-chalcone THXA were studied using experimental and computational methods. The importance of non-covalent interactions such as pi center dot center dot center dot pi, C-H center dot center dot center dot S, and C-H center dot center dot center dot pi was revealed.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Andrii Bazylevich, Leonid Patsenker, Sarit Aviel-Ronen, Gary Gellerman
Summary: Drug combination therapy is commonly used for treating various skin disorders, but its effectiveness is often limited. In this study, researchers synthesized conjugates of anti-pigmenting drugs and hyaluronic acid (HA) to improve treatment efficacy. These HA-drug conjugates exhibited measurable drug release profiles and demonstrated superior depigmentation effects compared to control groups in a swine model.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Xiaodan Ma, Xinlei Chen, Yaoqi Zhen, Xunjie Zheng, Chengzhe Shi, Shouwen Jin, Bin Liu, Bin Chen, Daqi Wang
Summary: Cocrystallization experiments between minoxidil and aryl acids coformers resulted in the successful formation of multi-component samples. The nature of these samples was determined using various techniques and their structural and supramolecular aspects were investigated. The outcomes revealed the importance of nonbonding contacts and different types of interactions in stabilizing and expanding the crystal structures.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Najla A. Alshaye, Magdy A. Ibrahim, Al-Shimaa Badran
Summary: The chemical behavior of 3-substituted-6,8-dimethylchromones towards phenylhydrazine was examined. Different reaction conditions produced various products, and the molecular geometries and reactivity descriptors of the compounds were also investigated. The results suggest that these compounds are suitable for nonlinear optical applications.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Hayette Alliouche, Houria Bouria, Rafik Bensegueni, Mounia Guergouri, Abdelmalek Bouraiou, Ali Belfaitah
Summary: In this paper, a combined experimental and theoretical study was conducted to synthesize and characterize new 2-quinolone-piperidine and -morpholine hybrids. The results from experiments were validated using computational calculations, and the affinity between these compounds and Acetylcholinesterase/Butyrylcholinesterase was estimated through molecular docking.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Wei-Min Chen, Juan-Juan Shao, Yi Zhang, Zhen-Dong Xue, Peng-Lai Liu, Jian-Ling Ni, Li-Zhuang Chen, Qiang Gao, Fang-Ming Wang
Summary: This study synthesized and characterized a novel Mn-based LMOF, and achieved good results in detecting heavy metal Al3+ in water, showing good stability, high selectivity and sensitivity. This provides new insights into the potential applications of Mn-based MOFs in chemical sensing.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Jun-Xia Li, Yi-Jing Lu, Ke-Ying Quan, Li-Bing Wu, Xun Feng, Wei-Zhou Wang
Summary: This study synthesized two cobalt(II) complexes and analyzed their crystal structures using single-crystal X-ray diffraction. The results showed that the crystal structures of these complexes were different, and they exhibited different crystal packing and magnetic properties.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Yang Li, Yan Zhang, Hong Xu, Min Li, Zhen Li, Zi-yu Song, Ji-shi Chen, Yan-Jun Liu, Yong Sun, Zhao Yang
Summary: This study reports the synthesis and solid-state characterization of a new pharmaceutical cocrystal, PRO-BPE, which can enhance the solubility of the highly water-insoluble prodrug probenecid. The PRO-BPE cocrystals were found to have superior water solubility compared to pure PRO. This research provides valuable insights into improving the solubility of poorly soluble drugs.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Lucas G. B. Felicio, Bianca B. M. Vieira, Ivana S. Lula, Renata Diniz, Frank Alexis, Flavio B. Miguz, Frederico B. De Sousa
Summary: A novel spiropyran derivative was synthesized for heavy metals sensing in water. The results demonstrated that the new derivative can serve as a rapid, sensitive, and simple tool for detecting Hg2+ ions in water with high selectivity.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Junqing Meng, Jie Wang, Lijuan Wang, Chunhui Lyu, Haiyan Chen, Yingpei Lyu, Baisheng Nie
Summary: Material modification with low surface energy can achieve lower surface free energy on micro-and nano-rough structures, which is crucial for developing superhydrophobic surfaces. In this study, attapulgite (APT) was modified with alkylamine, alkylammonium salt, and stearic acid, and the interaction between low surface materials and attapulgite was explained. The results showed that the hydrophobicity of APT was significantly modified by the modifiers, and the surface free energy of the composites first decreased and then increased with increasing molecular number of low surface energy monomers.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Karan Goswami, Dipak Das, Parthasarathi Bera, Sounak Roy, Md. Motin Seikh, Prasanta Kumar Sinha, Arup Gayen
Summary: This work presents the development of a simple and highly active heterogeneous Pd catalyst for Suzuki-Miyaura carbon-carbon cross-coupling reaction. The NiPdFe-1 catalyst shows the best activity and stability among the prepared catalysts. It efficiently promotes the coupling reaction between aryl bromide and phenyl boronic acid under mild reaction conditions with high isolated yields.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Chemistry, Physical
Ekta Pardhi, Devendra Singh Tomar, Rahul Khemchandani, Gananadhamu Samanthula, Pankaj Kumar Singh, Neelesh Kumar Mehra
Summary: The main aim of this study was to prepare a drug-drug coamorphous system to improve the physiochemical properties, solubility and stability of Apremilast and Indomethacin. Various solid-state characterization techniques were used to characterize the prepared system. Molecular level interactions were studied using molecular modeling and ATR-FTIR and 1H NMR. Solubility and dissolution studies showed the benefits of the coamorphous system. The system was found to be stable for a period of five months. Permeation study also demonstrated improved flux for both drugs compared to their crystalline forms. The coamorphous system showed anti-psoriatic and anti-melanogenic activity based on molecular docking results. Overall, the developed CAM-based supersaturated system exhibited improved physicochemical properties and physical stability.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
