Effect of Sodium Valproate Administration on Brain Neprilysin Expression and Memory in Rats

Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortex

(2011) Dorothee Aydin et al.   BMC GENOMICS

Mediator: the missing link in amyloid precursor protein nuclear signalling

(2011) Anthony J Turner et al.   EMBO REPORTS

Mediator is a transducer of amyloid-precursor-protein-dependent nuclear signalling

(2011) Xuan Xu et al.   EMBO REPORTS

Neuroprotection by Valproic Acid in Mouse Models of Permanent and Transient Focal Cerebral Ischemia

(2011) Yong Ri Qian et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Hypoxia-Induced Down-Regulation of Neprilysin by Histone Modification in Mouse Primary Cortical and Hippocampal Neurons

(2011) Zheng Wang et al.   PLoS One

The Transcriptionally Active Amyloid Precursor Protein (APP) Intracellular Domain Is Preferentially Produced from the 695 Isoform of APP in a β-Secretase-dependent Pathway

(2010) Nikolai D. Belyaev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone Deacetylase Inhibitor Valproic Acid Inhibits Cancer Cell Proliferation via Down-regulation of the Alzheimer Amyloid Precursor Protein

(2010) Vivek Venkataramani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell Death/Proliferation and Alterations in Glial Morphology Contribute to Changes in Diffusivity in the Rat Hippocampus after Hypoxia—Ischemia

(2010) Miroslava Anderova et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Valproic Acid Attenuates Blood–Brain Barrier Disruption in a Rat Model of Transient Focal Cerebral Ischemia: The Roles of HDAC and MMP-9 Inhibition

(2010) Zhifei Wang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Phosphorylation of APP-CTF-AICD domains and interaction with adaptor proteins: signal transduction and/or transcriptional role - relevance for Alzheimer pathology

(2010) Gennaro Schettini et al.   JOURNAL OF NEUROCHEMISTRY

Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer’s brain

(2010) Suqing Wang et al.   JOURNAL OF NEUROCHEMISTRY

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Targeting the correct HDAC(s) to treat cognitive disorders

(2010) André Fischer et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Biochemical, Molecular and Epigenetic Mechanisms of Valproic Acid Neuroprotection

(2010) Barbara Monti et al.   Current Molecular Pharmacology

Valproic acid as a promising agent to combat Alzheimer's disease

(2009) Xiu-Zhen Zhang et al.   BRAIN RESEARCH BULLETIN

Estrogen Stimulates Degradation of β-Amyloid Peptide by Up-regulating Neprilysin

(2009) Kaiwei Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The amyloid hypothesis for Alzheimer’s disease: a critical reappraisal

(2009) John Hardy   JOURNAL OF NEUROCHEMISTRY

Sodium valproate: an old drug with new roles

(2009) Natalia N. Nalivaeva et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Effects of acute and chronic physical exercise and stress on different types of memory in rats

(2008) Pâmela Billig Mello et al.   ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS

Amyloid-Degrading Enzymes as Therapeutic Targets in Alzheimers Disease

(2008) Natalia Nalivaeva et al.   Current Alzheimer Research

Neprilysin gene expression requires binding of the amyloid precursor protein intracellular domain to its promoter: implications for Alzheimer disease

(2008) Nikolai D Belyaev et al.   EMBO REPORTS

Valproic acid inhibits Aβ production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models

(2008) Hong Qing et al.   JOURNAL OF EXPERIMENTAL MEDICINE