The pathogenic Th profile of human activated memory Th cells in early rheumatoid arthritis can be modulated by VIP

Cutting Edge: Vasoactive Intestinal Peptide (VIP) Induces Differentiation of Th17 Cells with a Distinctive Cytokine Profile

(2014) M. Yadav et al.   JOURNAL OF IMMUNOLOGY

The roles of IFN-γ versus IL-17 in pathogenic effects of human Th17 cells on synovial fibroblasts

(2014) Hiroshi Kato et al.   Modern Rheumatology

Serum Levels of Vasoactive Intestinal Peptide as a Prognostic Marker in Early Arthritis

(2014) Carmen Martínez et al.   PLoS One

IL-17 family: Cytokines, receptors and signaling

(2013) Chunfang Gu et al.   CYTOKINE

Interleukin 17 contributes to the chronicity of inflammatory diseases such as rheumatoid arthritis

(2013) Giulia Benedetti et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Th17 cell development: from the cradle to the grave

(2013) Luis A. Zúñiga et al.   IMMUNOLOGICAL REVIEWS

Synovial Fibroblasts Directly Induce Th17 Pathogenicity via the Cyclooxygenase/Prostaglandin E2 Pathway, Independent of IL-23

(2013) S. M. J. Paulissen et al.   JOURNAL OF IMMUNOLOGY

VIP Modulates IL-22R1 Expression and Prevents the Contribution of Rheumatoid Synovial Fibroblasts to IL-22-Mediated Joint Destruction

(2013) Mar Carrión et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Inflammatory Mediators Alter Interleukin-17 Receptor, Interleukin-12 and -23 Expression in Human Osteoarthritic and Rheumatoid Arthritis Synovial Fibroblasts: Immunomodulation by Vasoactive Intestinal Peptide

(2013) Mar Carrión et al.   NEUROIMMUNOMODULATION

Distribution and functional plasticity of peripheral blood Th(c)17 and Th(c)1 in rheumatoid arthritis

(2013) Ana Henriques et al.   RHEUMATOLOGY INTERNATIONAL

Functional niche of inflamed synovium for Th17-cell expansion and activation in rheumatoid arthritis: Implication to clinical therapeutics

(2012) Weijia Dong et al.   AUTOIMMUNITY REVIEWS

Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR Review 1

(2012) Anthony J Harmar et al.   BRITISH JOURNAL OF PHARMACOLOGY

Frequency of Th17 CD4+ T Cells in Early Rheumatoid Arthritis: A Marker of Anti-CCP Seropositivity

(2012) Irene Arroyo-Villa et al.   PLoS One

Elevated Levels of T Helper 17 Cells Are Associated with Disease Activity in Patients with Rheumatoid Arthritis

(2012) Jimyung Kim et al.   Annals of Laboratory Medicine

Effect of VIP on the balance between cytokines and master regulators of activated helper T cells

(2011) Rebeca Jimeno et al.   IMMUNOLOGY AND CELL BIOLOGY

T helper 17 cell heterogeneity and pathogenicity in autoimmune disease

(2011) Kamran Ghoreschi et al.   TRENDS IN IMMUNOLOGY

Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production

(2010) J. P. van Hamburg et al.   ARTHRITIS AND RHEUMATISM

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) Daniel Aletaha et al.   ARTHRITIS AND RHEUMATISM

IFN-γ and IL-12 synergize to convert in vivo generated Th17 into Th1/Th17 cells

(2010) Maria H. Lexberg et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulation of the IL-21 Gene by the NF- B Transcription Factor c-Rel

(2010) G. Chen et al.   JOURNAL OF IMMUNOLOGY

Targeting interleukin-21 in rheumatoid arthritis

(2010) Feng-Lai Yuan et al.   MOLECULAR BIOLOGY REPORTS

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

(2010) K. Nistala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis

(2009) Hui Shen et al.   ARTHRITIS AND RHEUMATISM

Differential expression of vasoactive intestinal peptide and its functional receptors in human osteoarthritic and rheumatoid synovial fibroblasts

(2008) Yasmina Juarranz et al.   ARTHRITIS AND RHEUMATISM

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ

(2008) Xuexian O. Yang et al.   IMMUNITY

Immunoregulatory properties of vasoactive intestinal peptide in human T cell subsets: Implications for rheumatoid arthritis

(2007) Irene Gutiérrez-Cañas et al.   BRAIN BEHAVIOR AND IMMUNITY