Emerging roles of molecular chaperones and co-chaperones in selective autophagy: focus on BAG proteins

HspB8 and Bag3: A new chaperone complex targeting misfolded proteins to macroautophagy

(2014) Serena Carra et al.   Autophagy

BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins

(2011) Martin Gamerdinger et al.   EMBO REPORTS

BAG3 Directly Interacts with Mutated alphaB-Crystallin to Suppress Its Aggregation and Toxicity

(2011) Akinori Hishiya et al.   PLoS One

BAG3 directly associates with guanine nucleotide exchange factor of Rap1, PDZGEF2, and regulates cell adhesion

(2010) Masahiro Iwasaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Chaperone-Assisted Selective Autophagy Is Essential for Muscle Maintenance

(2010) Verena Arndt et al.   CURRENT BIOLOGY

Chaperone-mediated autophagy in protein quality control

(2010) Esperanza Arias et al.   CURRENT OPINION IN CELL BIOLOGY

The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS)

(2010) Valeria Crippa et al.   HUMAN MOLECULAR GENETICS

Identification of theDrosophilaOrtholog of HSPB8

(2010) Serena Carra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Co-chaperone BAG3 and adenovirus penton base protein partnership

(2010) E. Gout et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Selective autophagy: ubiquitin-mediated recognition and beyond

(2010) Claudine Kraft et al.   NATURE CELL BIOLOGY

Cellular strategies for controlling protein aggregation

(2010) Jens Tyedmers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The HSP70 chaperone machinery: J proteins as drivers of functional specificity

(2010) Harm H. Kampinga et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Proteasomal dysfunction in aging and Huntington disease

(2010) Xiao-Jiang Li et al.   NEUROBIOLOGY OF DISEASE

Ageing and protein aggregation-mediated disorders: from invertebrates to mammals

(2010) A. Dillin et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Caught in the middle: the role of Bag3 in disease: Figure 1

(2009) Andrea K. McCollum et al.   BIOCHEMICAL JOURNAL

Identification of the key structural motifs involved in HspB8/HspB6–Bag3 interaction

(2009) Margit Fuchs et al.   BIOCHEMICAL JOURNAL

Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3

(2009) Martin Gamerdinger et al.   EMBO JOURNAL

The role of molecular chaperones in human misfolding diseases

(2009) Sarah A. Broadley et al.   FEBS LETTERS

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

(2009) C. Hetz et al.   GENES & DEVELOPMENT

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies

(2008) S Sarkar et al.   CELL DEATH AND DIFFERENTIATION

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE