Article
Fisheries
G. A. Gayathri, P. Kavya, D. Ashwini, Eshika Chakraborty, Idris Adewale Ahmed, Gayathri Mahalingam
Summary: This study demonstrates that vitexin isolated from Acanthus ilicifolius leaf has antidiabetic effects by promoting GLUT-4 translocation and PPAR-gamma expression in high-fat diet-streptozotocin induced rats. It significantly lowers blood glucose levels and improves other biochemical parameters. In addition, vitexin increases the mRNA expression of GLUT-4 and PPAR-gamma in diabetic rats.
AQUACULTURE INTERNATIONAL
(2023)
Article
Cell Biology
Junxia Feng, Meizhi Lu, Wenhao Li, Jingchun Li, Ping Meng, Zukai Li, Xuejuan Gao, Yunfang Zhang
Summary: This study found that PPAR gamma can inhibit the progression of high glucose-induced peritoneal fibrosis by increasing GLUT1 expression and suppressing peritoneal mesothelial cell proliferation.
MOLECULAR AND CELLULAR BIOCHEMISTRY
(2022)
Article
Environmental Sciences
Sonam Tripathi, Sangeeta Yadav, Pooja Sharma, Diane Purchase, Asad Syed, Ram Chandra
Summary: This study found that elevated levels of physico-chemical pollution were present in distillery sludges despite anaerobic digestion treatment. The invasive grass species Cynodon dactylon L. and its rhizobacteria showed good capacity to remediate the sludge and improve its physico-chemical parameters.
ENVIRONMENTAL RESEARCH
(2022)
Article
Nutrition & Dietetics
Elisabetta Melloni, Silvia Grassilli, Arianna Romani, Erika Rimondi, Annalisa Marcuzzi, Enrico Zauli, Paola Secchiero, Guglielmo Paganetto, Alessandra Guerrini, Gianni Sacchetti, Massimo Tacchini
Summary: Convolvulus pluricaulis is a commonly used Indian herb in Ayurvedic medicine known for its neuroprotective and neuroinflammatory action. Recent studies have shown its involvement in lipidic and glucidic metabolism, particularly in the control of hyperlipidaemia and diabetic conditions. It has been found to promote adipocyte differentiation and regulate glucose metabolism through the modulation of key regulators such as PPAR gamma and GLUT-4. Additionally, it exhibits anti-inflammatory effects by downregulating cytokines associated with insulin resistance and glucose intolerance. These findings suggest that Convolvulus pluricaulis could have potential benefits in glycemia and may be used as an adjunctive treatment for diabetes or for better glucose control.
Article
Environmental Sciences
Xiliang Song, Changjiang Li, Weifeng Chen
Summary: Soils contaminated with PAHs and Cd have significant impacts on the environment and human health. A pot experiment was conducted to investigate the phytoremediation potential of Bermuda grass grown in co-contaminated soils. The results showed that Bermuda grass exhibited decreased growth and increased oxidative stress when grown in contaminated soils. However, it also showed a remarkable ability to degrade PAHs and accumulate Cd.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Review
Oncology
Monika Pliszka, Leszek Szablewski
Summary: Cancer cells prefer glycolysis for ATP production due to hypoxia; overexpression of glucose transporters promotes carcinogenesis and may have beneficial effects; inhibiting glucose transporters could be a treatment method for cancer patients.
Article
Biochemistry & Molecular Biology
Huilan Zeng, Alina V. Dumitrescu, David Wadkins, Benjamin W. Elwood, Oliver W. Gramlich, Markus H. Kuehn
Summary: Neuroinflammation is a significant factor in the pathophysiology of neurodegenerative diseases, including glaucoma. Pioglitazone, an agonist of PPAR gamma, shows potential in protecting retinal ganglion cells and reversing vision loss in glaucomatous retina.
Article
Chemistry, Medicinal
Samuel Estrada-Soto, Kathia Ornelas-Mendoza, Gabriel Navarrete-Vazquez, Fabiola Chavez-Silva, Julio Cesar Almanza-Perez, Rafael Villalobos-Molina, Erandi Ortiz-Barragan, Hilda Loza-Rodriguez, Julio Cesar Rivera-Leyva, Angelica Flores-Flores, Irene Perea-Arango, Javier-German Rodriguez-Carpena, Gabriela Avila-Villarreal
Summary: The hydroalcoholic extract of Plantago australis showed significant antidiabetic action by insulin sensitization through PPAR?/GLUT-4 overexpression, as well as inhibition of a-glucosidase. It also did not exhibit toxicity in in vivo studies.
Review
Endocrinology & Metabolism
Maria Anna Bantounou, Panagiotis Sardellis, Rosa Thuemmler, Daniel Black Boada, Justyna Kaczmarek, Ribeya Mahmood, Josip Plascevic, Sam Philip
Summary: This study investigated the renal safety profile of sotagliflozin, a new inhibitor of sodium-glucose co-transporter-1 and -2, in patients with type 1 and type 2 diabetes. The results showed that sotagliflozin did not adversely affect renal function and did not change the risk of key renal outcomes, even in patients with pre-existing renal impairment.
DIABETES OBESITY & METABOLISM
(2023)
Letter
Cardiac & Cardiovascular Systems
Bo Liang, Ning Gu
Summary: The 2022 AHA/ACC/HFSA guideline for heart failure management recommends the use of sodium-glucose co-transporter-2 inhibitors in patients with heart failure and type 2 diabetes to manage hyperglycemia and reduce heart failure-related morbidity and mortality. However, it should be noted that this recommendation is based on specific trials and does not include recently published studies.
CARDIOVASCULAR DIABETOLOGY
(2022)
Review
Cell Biology
Ivana Vrhovac Madunic, Valentina Karin-Kujundzic, Josip Madunic, Ida Marija Sola, Ljiljana Serman
Summary: Glucose metabolism in the endometrium plays a crucial role in pregnancy outcomes, with ten glucose transporters expressed in rodents and humans, including GLUT1, GLUT3, GLUT4, and GLUT8. The recent discovery of SGLT1 in the mouse and human endometrium emphasizes its importance in regulating glycogen accumulation for embryo implantation. Investigating the function of glucose transporters in different endometrial cells is essential, as they are associated with infertility, polycystic ovary syndrome, and gestational diabetes.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Xiaohui Ji, Wenqian Zhang, Liqin Yin, Zunhan Shi, Jinwen Luan, Linshan Chen, Longhua Liu
Summary: The number of patients with type 2 diabetes is increasing, posing challenges to public health and economic development. Peroxisome proliferator-activated receptor gamma (PPAR gamma) has been identified as a potential drug target for the treatment of type 2 diabetes. Post-translational modifications (PTMs) of PPAR gamma offer a promising approach to develop safer compounds for diabetes treatment.
Article
Biochemistry & Molecular Biology
Fenghua Qian, Brooke E. Arner, Kathleen M. Kelly, Charyguly Annageldiyev, Arati Sharma, David F. Claxton, Robert F. Paulson, K. Sandeep Prabhu
Summary: Interleukin-4 (IL-4) plays a therapeutic role in acute myeloid leukemia (AML) by alleviating the severity of the disease. IL-4 enhances the expression of hematopoietic- PGD(2) synthase (H-PGDS) to increase the production of endogenous cyclopentenone prostaglandins (CyPGs), leading to apoptosis of leukemia-initiating cells (LICs).
Article
Chemistry, Medicinal
Chunyan Wang, Zhengyun Chen, Xianlei Zhao, Cuicui Lin, Shenghui Hong, Yuhan Lou, Xiaomeng Shi, Mengdan Zhao, Xiaohang Yang, Min-Xin Guan, Yongmei Xi
Summary: The study demonstrated that resveratrol treatment exhibited efficient therapeutic effects for endometriosis model rats, potentially through its important roles in anti-inflammation, immunoregulation, and lipid-related metabolism regulation.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2021)
Article
Food Science & Technology
Dushyant Kshatriya, Lihong Hao, Nicholas T. Bello
Summary: This study found that raspberry ketone has a dose-dependent metabolic signature in white adipose tissue of mice, which is associated with weight control and loss of righting reflex. Raspberry ketone can regulate gene expression related to weight control and metabolic effects in adipose tissue.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Article
Cell Biology
Michael J. Herriges, David J. Tischfield, Zheng Cui, Michael P. Morley, Yumiao Han, Apoorva Babu, Su Li, MinMin Lu, Isis Cendan, Benjamin A. Garcia, Stewart A. Anderson, Edward E. Morrisey
GENES & DEVELOPMENT
(2017)
Article
Biochemistry & Molecular Biology
Christina Yingxian Chen, Matthew A. Caporizzo, Kenneth Bedi, Alexia Vite, Alexey Bogush, Patrick Robison, Julie G. Heffler, Alex K. Salomon, Neil A. Kelly, Apoorva Babu, Michael P. Morley, Kenneth B. Margulies, Benjamin L. Prosser
Article
Multidisciplinary Sciences
David B. Frank, Ian J. Penkala, Jarod A. Zepp, Aravind Sivakumar, Ricardo Linares-Saldana, William J. Zacharias, Katharine G. Stolz, Josh Pankina, MinQi Lu, Qiaohong Wang, Apoorva Babu, Li Li, Su Zhou, Michael P. Morley, Rajan Jain, Edward E. Morrisey
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2019)
Article
Cell Biology
Rebecca Windmueller, John P. Leach, Apoorva Babu, Su Zhou, Michael P. Morley, Aoi Wakabayashi, Nataliya B. Petrenko, Patrick Viatour, Edward E. Morrisey
Article
Biology
Terren K. Niethamer, Collin T. Stabler, John P. Leach, Jarod A. Zepp, Michael P. Morley, Apoorva Babu, Su Zhou, Edward E. Morrisey
Article
Multidisciplinary Sciences
Jarod A. Zepp, Michael P. Morley, Claudia Loebel, Madison M. Kremp, Fatima N. Chaudhry, Maria C. Basil, John P. Leach, Derek C. Liberti, Terren K. Niethamer, Yun Ying, Sowmya Jayachandran, Apoorva Babu, Su Zhou, David B. Frank, Jason A. Burdick, Edward E. Morrisey
Summary: Through a multimodal approach, AT1 epithelial cells were identified as a signaling hub in the transition to air breathing at birth, aligning with force-exerting myofibroblasts to drive alveolar formation. Biophysical forces and AT1-derived paracrine signals together drive the alignment of cell fates, leading to extensive tissue remodeling required for postnatal respiration.
Article
Cell Biology
Quentin McAfee, Christina Yingxian Chen, Yifan Yang, Matthew A. Caporizzo, Michael Morley, Apoorva Babu, Sunhye Jeong, Jeffrey Brandimarto, Kenneth C. Bedi, Emily Flam, Joseph Cesare, Thomas P. Cappola, Kenneth Margulies, Benjamin Prosser, Zolt Arany
Summary: Truncated titin proteins were quantitatively detected in human DCM hearts with TTNtvs, while full-length titin was reduced in TTNtvs(+) DCM hearts. Disease severity did not correlate with TTNtv location, and transcriptomic profiling showed few differences between TTNtv(+) and TTNtv(-) DCM hearts. Contractility in isolated human adult cardiomyocytes from TTNtv(+) DCM hearts did not show defects compared to TTNtv(-) hearts, supporting a combined dominant-negative and haploinsufficiency mechanism in disease.
SCIENCE TRANSLATIONAL MEDICINE
(2021)
Meeting Abstract
Biochemistry & Molecular Biology
Jeremy Katzen, Luis Rodriguez, Yaniv Tomer, Apoorva Babu, Ming Zhao, Aditi Murthy, Michael Morley, Surafel Mulugeta, Timothy Pelura, Glenn Rosen, Michaell F. Beers
Article
Multidisciplinary Sciences
Maria C. Basil, Fabian L. Cardenas-Diaz, Jaymin J. Kathiriya, Michael P. Morley, Justine Carl, Alexis N. Brumwell, Jeremy Katzen, Katherine J. Slovik, Apoorva Babu, Su Zhou, Madison M. Kremp, Katherine B. McCauley, Shanru Li, Joseph D. Planer, Shah S. Hussain, Xiaoming Liu, Rebecca Windmueller, Yun Ying, Kathleen M. Stewart, Michelle Oyster, Jason D. Christie, Joshua M. Diamond, John F. Engelhardt, Edward Cantu, Steven M. Rowe, Darrell N. Kotton, Harold A. Chapman, Edward E. Morrisey
Summary: This study reveals the existence of a unique population of secretory cells in the respiratory bronchioles of the human lung, which act as unidirectional progenitors for alveolar type 2 cells. The differentiation of these respiratory airway secretory cells into alveolar type 2 cells is regulated by Notch and Wnt signaling. These findings highlight the importance of this distinct progenitor cell population in maintaining the gas-exchange compartment and its potential role in chronic lung diseases.
Article
Biology
Derek C. Sung, Xiaowen Chen, Mei Chen, Jisheng Yang, Susan Schultz, Apoorva Babu, Yitian Xu, Siqi Gao, T. C. Stevenson Keller, Patricia Mericko-Ishizuka, Michelle Lee, Ying Yang, Joshua P. Scallan, Mark L. Kahn
Summary: This study shows that VE-cadherin plays a crucial role in trophoblast migration and endovascular invasion during placental development in mice. Deficiency of VE-cadherin results in failure of spiral artery remodeling, decreased maternal blood flow into the placenta, and fetal growth restriction. These findings highlight a non-endothelial function of VE-cadherin in trophoblasts and suggest that endothelial proteins may have unique roles in these cells.
Article
Biology
Rafael Jesus Fernandez, Zachary J. G. Gardner, Katherine J. Slovik, Derek C. Liberti, Katrina N. Estep, Wenli Yang, Qijun Chen, Garrett T. Santini, Javier Perez, Sarah Root, Ranvir Bhatia, John W. Tobias, Apoorva Babu, Michael P. Morley, David B. Frank, Edward E. Morrisey, Christopher J. Lengner, F. Brad Johnson
Summary: DC is a rare genetic disorder that causes short telomeres and early onset of age-related diseases. Using iAT2 cells to model, it is shown that shortened telomeres lead to cell senescence and Wnt signaling defects. The study suggests that Wnt agonists may be potential therapies for DC-related pathologies.
Article
Cell Biology
Derek C. Liberti, William A. Liberti, Madison M. Kremp, Ian J. Penkala, Fabian L. Cardenas-Diaz, Michael P. Morley, Apoorva Babu, Su Zhou, Rafael J. Fernandez, Edward E. Morrisey
Summary: The transcription factor Klf5 plays a crucial role in determining the fate of alveolar epithelial cells, enforcing the accuracy of AT1 cell lineage and inhibiting AT2 cell proliferation during lung development and regeneration.
DEVELOPMENTAL CELL
(2022)
Article
Biotechnology & Applied Microbiology
Sellappan Mohan, Jayagopal Dharani, Ramanathan Natarajan, Arumugam Nagarajan
Summary: COVID-19 is a global pandemic and finding new drugs for its treatment is crucial. Some drugs used for other diseases have been repurposed for COVID-19 treatment. In a study, 68 GPR-120 agonists were docked and ten compounds showed potential for SAR-CoV-2 treatment.
JOURNAL OF GENETIC ENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Multidisciplinary Sciences
Kseniya Obraztsova, Maria C. Basil, Ryan Rue, Aravind Sivakumar, Susan M. Lin, Alexander R. Mukhitov, Andrei Gritsiuta, Jilly F. Evans, Meghan Kopp, Jeremy Katzen, Annette Robichaud, Elena N. Atochina-Vasserman, Shanru Li, Justine Carl, Apoorva Babu, Michael P. Morley, Edward Cantu, Michael F. Beers, David B. Frank, Edward E. Morrisey, Vera P. Krymskaya
NATURE COMMUNICATIONS
(2020)
Article
Biochemistry & Molecular Biology
Andrey Poleshko, Parisha P. Shah, Mudit Gupta, Apoorva Babu, Michael P. Morley, Lauren J. Manderfield, Jamie L. Ifkovits, Damelys Calderon, Haig Aghajanian, Javier E. Sierra-Pagan, Zheng Sun, Qiaohong Wang, Li Li, Nicole C. Dubois, Edward E. Morrisey, Mitchell A. Lazar, Cheryl L. Smith, Jonathan A. Epstein, Rajan Jain
Article
Biochemical Research Methods
Nousheen Parvaiz, Asma Abro, Syed Sikander Azam
Summary: Protein Tyrosine Phosphatase 1B (PTP1B) is a negative regulator of insulin signaling pathways and has potential as a medicinal target. This study explores the binding and conformational orientation of zinc(II) complexes in PTP1B using advanced computational methods. The findings suggest that zinc(II) complexes can bind to important residues in the enzyme and inhibit its activity.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
(2024)
Article
Biochemical Research Methods
Hira Zubair, Muhamed Salim Akhter, Muhammad Waqas, Mariam Ishtiaq, Ijaz Ahmed Bhatti, Javed Iqbal, Ahmed M. Skawky, Rasheed Ahmad Khera
Summary: Improving open-circuit voltage is crucial for enhancing the overall efficiency of organic solar cells. This study successfully improved the open-circuit voltage by modulating the molecular structure and proposed a promising design concept for acceptor molecules that may contribute to the development of advanced organic solar cells.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
(2024)
Article
Biochemical Research Methods
Jerica Wilson, Bahrad A. Sokhansanj, Wei Chuen Chong, Rohan Chandraghatgi, Gail L. Rosen, Hai-Feng Ji
Summary: Fragment-based drug design is a computer-aided drug discovery method, however, it has limitations in processing time and success rate. In this study, a new method called Fragment Databases from Screened Ligands Drug Design (FDSL-DD) was proposed, which intelligently incorporates fragment characteristics into the drug design process to improve the binding affinity between drugs and protein targets.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
(2024)
Article
Biochemical Research Methods
M. Chamani, G. H. Farrahi
Summary: This paper employs the Generalized Particle (GP) method to simulate nanoindentation and nanoscratching, showing that this method maintains consistent atomic properties across different scales and achieves results consistent with full atomic simulations.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
(2024)
Article
Biochemical Research Methods
Paola Vottero, Elena Carlotta Olivetti, Lucia Chiara D'Agostino, Luca Di Grazia, Enrico Vezzetti, Maral Aminpour, Jacek Adam Tuszynski, Federica Marcolin
Summary: This study aims to characterize the spike protein of the SARS-CoV-2 virus and investigate its interaction with the ACE2 receptor using a geometric analysis. The 3D depth maps of the proteins are filtered using a specific convolutional filter to obtain geometric features. Geometric descriptors and a Support Vector Machine classifier are used for feature extraction and classification, revealing the geometrical reasons for the higher contagiousness of the Omicron variant compared to other variants.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
(2024)
Article
Biochemical Research Methods
Diana Margarita Mojica-Munoz, Karla Lizbeth Macias-Sanchez, Estefania Odemaris Juarez-Hernandez, Aurora Rodriguez-Alvarez, Jean-Michel Grevy, Armando Diaz-Valle, Mauricio Carrillo-Tripp, Jose Marcos Falcon-Gonzalez
Summary: By employing molecular dynamics simulations, we investigated the molecular mechanisms underlying the plasticization of starch. Our study revealed that chain size affects the solubility of starch, temperature influences its diffusivity and elastic properties, and oleic acid shows potential as an alternative plasticizer. Blending glycerol or oleic acid with water enhances the elasticity of starch.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
(2024)
Article
Biochemical Research Methods
Sandip Kumar Baidya, Suvankar Banerjee, Balaram Ghosh, Tarun Jha, Nilanjan Adhikari
Summary: This study utilized classification-based QSAR techniques and fragment-based data mining to analyze different MMP-9 inhibitors, revealing the importance of certain molecular fragments in MMP-9 inhibition. These findings have implications for the development of effective MMP-9 inhibitors in the future.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
(2024)
Article
Biochemical Research Methods
Farid Faraji Chanzab, Saber Mohammadi, Fatemeh Alemi Mahmoudi
Summary: A comprehensive study using molecular dynamics technique was conducted to investigate the behavior of PAP molecules in a n-heptane/toluene solution and the role of SWCNTs, both bare and functionalized with carboxyl groups, in the aggregation of PAP molecules. The study found that the CNTs hindered the association of PAP molecules through steric hindrance and adsorption mechanisms. The presence of carboxyl groups on the CNTs improved the stability and adsorption of PAP molecules. The results have implications for future research on controlling asphaltene precipitation in the oil industry.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
(2024)
Article
Biochemical Research Methods
Ramin Bairami Habashi, Mohammad Najafi, Reza Zarghami
Summary: A vigorous Monte Carlo strategy was developed to simulate the copolymerization of ethylene and 1-butene using a dual-site metallocene catalyst. The results showed that the second catalyst site had higher activity than the first site, with ethylene and 1-butene consumption rates five times higher and hydrogen transfer rates three times faster. The molar percentage of 1-butene in the copolymers synthesized from the second site was around 12%, while in the copolymers from the first site it was around 2%. Increasing the 1-butene concentration led to an increase in overall molecular weight, while increasing the hydrogen concentration resulted in a decrease in molecular weight. The ratio of ethylene to 1-butene affected the melt index and the weight fraction of crystals, with higher ratios leading to smaller melt indexes and higher weight fractions of crystals. Increasing the temperature caused changes in molecular weight, bimodal molecular weight distribution, crystal thickness and weight fraction, and density of HDPE.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
(2024)
Article
Biochemical Research Methods
Yufan Lu, Xingmin Guo, Shuya Liu
Summary: This paper investigates how to control the nontrivial topological structures of DNA nanocages by adjusting the number of ssDNA strands. A new algorithm and program are developed to calculate the component number of polyhedral links, filling the gap in computer programs on this aspect. The study provides a complete list of topological structures with different component numbers for DNA octahedrons assembled from one or more ssDNA strands.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
(2024)
Article
Biochemical Research Methods
Peng Cui, Shideng Yuan, Heng Zhang, Shiling Yuan
Summary: Understanding the mechanisms of viscosity enhancement in crude oil phases is crucial for optimizing extraction and transportation processes. This study employed molecular dynamics simulations to investigate the behavior and viscosification mechanism of asphaltene molecules in complex oil phases. The research suggests that electrostatic interactions and interactions between asphaltene and crude oil molecules contribute to the enhanced viscosity. The findings provide insight into the viscosity enhancement mechanisms in crude oil phases.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
(2024)
Article
Biochemical Research Methods
Kun Lv, Jin Zhang, Xiaohua Liu, Yuqiao Zhou, Kai Liu
Summary: In this paper, the authors propose a robust method for evaluating the interactions between chiral catalysts and substrates using computer simulations. The method involves constructing 3D models from point cloud data, filtering out non-interacting points, determining interacting points, and accurately calculating interacted volumes. Experimental results demonstrate the effectiveness of the method in removing non-interacting points and calculating interacted volumes with low errors.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
(2024)
Article
Biochemical Research Methods
Crisciele Fontana, Joao Luiz de Meirelles, Hugo Verli
Summary: By using the GROMOS force field and molecular simulations, this study assessed the dynamics of STA-analogs in aqueous solution and their interaction with water, expanding the knowledge of the conformational space of these ligands and providing potential implications for understanding conformational selection during complexation.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
(2024)
Article
Biochemical Research Methods
Wei Zhao, Wenjie Zou, Fengyang Liu, Fang Zhou, N. Emre Altun
Summary: The effect of grafting rate on the water solubility of chitosan-grafted polyacrylamide (Chi-gPAM) was investigated using molecular dynamics simulations. The results showed that the intramolecular hydrogen bonding of Chi-gPAM played a dominant role in its water solubility. Additionally, the interaction between Chi-gPAM and water increased with grafting rate.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
(2024)
Article
Biochemical Research Methods
Nassima Bachir, Samir Kenouche, Jorge I. Martinez-Araya
Summary: This study investigates the local chemical reactivity of FOX-7 and explores the interaction between the compound and different metals. The findings suggest that the stability and charge transfers of the compound are influenced by the metal involved, and the interaction between Metallocene Methyl Cations and the compound shows potential for neutralization.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
(2024)