The non-human primate model of tuberculosis

The Mycobacterium tuberculosis Stress Response Factor SigH Is Required for Bacterial Burden as Well as Immunopathology in Primate Lungs

(2012) Smriti Mehra et al.   JOURNAL OF INFECTIOUS DISEASES

Stereological analysis of bacterial load and lung lesions in nonhuman primates (rhesus macaques) experimentally infected with Mycobacterium tuberculosis

(2011) Paul A. Luciw et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Disseminated tuberculosis in human immunodeficiency virus infection: ineffective immunity, polyclonal disease and high mortality

(2011) C. F. von Reyn et al.   INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE

The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection

(2011) Philana Ling Lin et al.   JOURNAL OF CLINICAL INVESTIGATION

Membrane-Bound IL-22 after De Novo Production in Tuberculosis and Anti-Mycobacterium tuberculosis Effector Function of IL-22+ CD4+ T Cells

(2011) G. Zeng et al.   JOURNAL OF IMMUNOLOGY

Simian Immunodeficiency Virus-Induced Changes in T Cell Cytokine Responses in Cynomolgus Macaques with Latent Mycobacterium tuberculosis Infection Are Associated with Timing of Reactivation

(2011) J. T. Mattila et al.   JOURNAL OF IMMUNOLOGY

Reactivation of latent tuberculosis in rhesus macaques by coinfection with simian immunodeficiency virus

(2011) Smriti Mehra et al.   JOURNAL OF MEDICAL PRIMATOLOGY

Aerosol exposure to Zaire ebolavirus in three nonhuman primate species: differences in disease course and clinical pathology

(2011) Douglas S. Reed et al.   MICROBES AND INFECTION

Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection

(2011) Christopher B Ford et al.   NATURE GENETICS

Large Scale Comparison of Innate Responses to Viral and Bacterial Pathogens in Mouse and Macaque

(2011) Guy Zinman et al.   PLoS One

Extended safety and efficacy studies of a live attenuated double leucine and pantothenate auxotroph of Mycobacterium tuberculosis as a vaccine candidate

(2011) Samantha L. Sampson et al.   VACCINE

Cowpox virus infection of cynomolgus macaques as a model of hemorrhagic smallpox

(2011) Reed F. Johnson et al.   VIROLOGY

High-Resolution Phenotypic Profiling Defines Genes Essential for Mycobacterial Growth and Cholesterol Catabolism

(2011) Jennifer E. Griffin et al.   PLoS Pathogens

Establishment of an Aerosol Challenge Model of Tuberculosis in Rhesus Macaques and an Evaluation of Endpoints for Vaccine Testing

(2010) S. A. Sharpe et al.   Clinical and Vaccine Immunology

From HIV to Tuberculosis and Back Again: A Tale of Activism in 2 Pandemics

(2010) Mark Harrington   CLINICAL INFECTIOUS DISEASES

Functional Analysis of Molybdopterin Biosynthesis in Mycobacteria Identifies a Fused Molybdopterin Synthase in Mycobacterium tuberculosis

(2010) M. J. Williams et al.   JOURNAL OF BACTERIOLOGY

Sm‐p80–Based DNA Vaccine Provides Baboons with Levels of Protection againstSchistosomamansoniInfection Comparable to Those Achieved by the Irradiated Cercarial Vaccine

(2010) Weidong Zhang et al.   JOURNAL OF INFECTIOUS DISEASES

Protection of Rhesus Macaques from Vaginal Infection by Vaginally Delivered Maraviroc, an Inhibitor of HIV‐1 Entry via the CCR5 Co‐Receptor

(2010) Ronald S. Veazey et al.   JOURNAL OF INFECTIOUS DISEASES

Genetic Requirements for the Survival of Tubercle Bacilli in Primates

(2010) Noton K. Dutta et al.   JOURNAL OF INFECTIOUS DISEASES

CD4+Regulatory T Cells in a Cynomolgus Macaque Model ofMycobacterium tuberculosisInfection

(2010) Angela M. Green et al.   JOURNAL OF INFECTIOUS DISEASES

PersistentPneumocystisColonization Leads to the Development of Chronic Obstructive Pulmonary Disease in a Nonhuman Primate Model of AIDS

(2010) Timothy W. Shipley et al.   JOURNAL OF INFECTIOUS DISEASES

Reactivation of Latent Tuberculosis in Cynomolgus Macaques Infected with SIV Is Associated with Early Peripheral T Cell Depletion and Not Virus Load

(2010) Collin R. Diedrich et al.   PLoS One

Development of an Acute and Highly Pathogenic Nonhuman Primate Model of Nipah Virus Infection

(2010) Thomas W. Geisbert et al.   PLoS One

Transcriptional Reprogramming in Nonhuman Primate (Rhesus Macaque) Tuberculosis Granulomas

(2010) Smriti Mehra et al.   PLoS One

Immunogenicity and protective efficacy of a DNA vaccine against Venezuelan equine encephalitis virus aerosol challenge in nonhuman primates

(2010) Lesley C. Dupuy et al.   VACCINE

Pathology of Inhalational Anthrax Animal Models

(2010) N. A. Twenhafel   VETERINARY PATHOLOGY

Role of nonhuman primates in the evaluation of candidate AIDS vaccines: an industry perspective

(2010) Silvija I Staprans et al.   Current Opinion in HIV and AIDS

Simian immunodeficiency virus macaque models of HIV latency

(2010) Jesse D Deere et al.   Current Opinion in HIV and AIDS

Differentiation, Distribution and γδ T Cell-Driven Regulation of IL-22-Producing T Cells in Tuberculosis

(2010) Shuyu Yao et al.   PLoS Pathogens

Quantitative Comparison of Active and Latent Tuberculosis in the Cynomolgus Macaque Model

(2009) P. L. Lin et al.   INFECTION AND IMMUNITY

Chlamydia trachomatis Native Major Outer Membrane Protein Induces Partial Protection in Nonhuman Primates: Implication for a Trachoma Transmission-Blocking Vaccine

(2009) L. Kari et al.   JOURNAL OF IMMUNOLOGY

MVA.85A Boosting of BCG and an Attenuated, phoP Deficient M. tuberculosis Vaccine Both Show Protective Efficacy Against Tuberculosis in Rhesus Macaques

(2009) Frank A. W. Verreck et al.   PLoS One

Defined tuberculosis vaccine, Mtb72F/AS02A, evidence of protection in cynomolgus monkeys

(2009) S. G. Reed et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tuberculous Granuloma Induction via Interaction of a Bacterial Secreted Protein with Host Epithelium

(2009) H. E. Volkman et al.   SCIENCE

Determination of lesion volume by MRI and stereology in a macaque model of tuberculosis

(2009) S.A. Sharpe et al.   TUBERCULOSIS

Efficacy and safety of live attenuated persistent and rapidly cleared Mycobacterium tuberculosis vaccine candidates in non-human primates

(2009) Michelle H. Larsen et al.   VACCINE

A Critical Role for CD8 T Cells in a Nonhuman Primate Model of Tuberculosis

(2009) Crystal Y. Chen et al.   PLoS Pathogens

Monovalent virus-like particle vaccine protects guinea pigs and nonhuman primates against infection with multiple Marburg viruses

(2008) Dana L Swenson et al.   Expert Review of Vaccines

Extrapulmonary Dissemination of Mycobacterium bovis but Not Mycobacterium tuberculosis in a Bronchoscopic Rabbit Model of Cavitary Tuberculosis

(2008) G. G. Nedeltchev et al.   INFECTION AND IMMUNITY

Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates

(2008) L. E. Via et al.   INFECTION AND IMMUNITY

Severe Tuberculosis Induces Unbalanced Up‐Regulation of Gene Networks and Overexpression ofIL‐22, MIP‐1α, CCL27, IP‐10, CCR4, CCR5, CXCR3, PD1, PDL2, IL‐3, IFN‐β, TIM1,andTLR2but Low Antigen‐Specific Cellular Responses

(2008) Liyou Qiu et al.   JOURNAL OF INFECTIOUS DISEASES

Protective efficacy of recombinant BCG Tokyo (Ag85A) in rhesus monkeys (Macaca mulatta) infected intratracheally with H37Rv Mycobacterium tuberculosis

(2008) I. Sugawara et al.   TUBERCULOSIS