A high-fat diet suppresses de novo lipogenesis and desaturation but not elongation and triglyceride synthesis in mice

Pathway-selective Insulin Resistance and Metabolic Disease: The Importance of Nutrient Flux

(2014) Yolanda F. Otero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Omega-3 Fatty Acids, Hepatic Lipid Metabolism, and Nonalcoholic Fatty Liver Disease

(2013) E. Scorletti et al.   Annual Review of Nutrition

A Central Role for mTOR in Lipid Homeostasis

(2013) Dudley W. Lamming et al.   Cell Metabolism

Stearoyl-CoA Desaturase 1 Is a Novel Molecular Therapeutic Target for Clear Cell Renal Cell Carcinoma

(2013) C. A. von Roemeling et al.   CLINICAL CANCER RESEARCH

The multifaceted role of mTORC1 in the control of lipid metabolism

(2013) Stéphane J H Ricoult et al.   EMBO REPORTS

Increased De Novo Lipogenesis Is a Distinct Characteristic of Individuals With Nonalcoholic Fatty Liver Disease

(2013) Jennifer E. Lambert et al.   GASTROENTEROLOGY

Noninvasive Measurement of Murine Hepatic Acetyl-CoA13C-Enrichment Following Overnight Feeding with13C-Enriched Fructose and Glucose

(2013) Filipa Carvalho et al.   Biomed Research International

Inflammation and Lipid Signaling in the Etiology of Insulin Resistance

(2012) Christopher K. Glass et al.   Cell Metabolism

Elovl6 promotes nonalcoholic steatohepatitis

(2012) Takashi Matsuzaka et al.   HEPATOLOGY

Acetyl-CoA Carboxylase 2−/−Mutant Mice are Protected against Fatty Liver under High-fat, High-carbohydrate Dietary andde NovoLipogenic Conditions

(2012) Lutfi Abu-Elheiga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elovl5 regulates the mTORC2-Akt-FOXO1 pathway by controlling hepaticcis-vaccenic acid synthesis in diet-induced obese mice

(2012) Sasmita Tripathy et al.   JOURNAL OF LIPID RESEARCH

Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver

(2012) Santhosh Satapati et al.   JOURNAL OF LIPID RESEARCH

Stearoyl CoA Desaturase 1: Role in Cellular Inflammation and Stress

(2012) Xueqing Liu et al.   Advances in Nutrition

Insulin signaling to hepatic lipid metabolism in health and disease

(2011) Karla F. Leavens et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Quantifying cholesterol synthesis in vivo using2H2O: enabling back-to-back studies in the same subject

(2011) Stephen F. Previs et al.   JOURNAL OF LIPID RESEARCH

Identifying Static and Kinetic Lipid Phenotypes by High Resolution UPLC–MS: Unraveling Diet-Induced Changes in Lipid Homeostasis by Coupling Metabolomics and Fluxomics

(2011) Jose M. Castro-Perez et al.   JOURNAL OF PROTEOME RESEARCH

Genetic control ofde novolipogenesis: role in diet-induced obesity

(2010) Maggie S. Strable et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Phosphoenolpyruvate carboxykinase (Pck1) helps regulate the triglyceride/fatty acid cycle and development of insulin resistance in mice

(2010) Carrie A. Millward et al.   JOURNAL OF LIPID RESEARCH

Elevated hepatic fatty acid elongase-5 activity corrects dietary fat-induced hyperglycemia in obese BL/6J mice

(2010) Sasmita Tripathy et al.   JOURNAL OF LIPID RESEARCH

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

(2010) Shijie Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Akt2 Is Required for Hepatic Lipid Accumulation in Models of Insulin Resistance

(2009) Karla F. Leavens et al.   Cell Metabolism

A novel model of type 2 diabetes mellitus based on obesity induced by high-fat diet in BDF1 mice

(2009) Hiroshi Karasawa et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

High Fat Feeding Induces Hepatic Fatty Acid Elongation in Mice

(2009) Maaike H. Oosterveer et al.   PLoS One

Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors

(2008) Zhili Xin et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Triglyceride Synthesis in Epididymal Adipose Tissue

(2008) Ilya R. Bederman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice

(2008) Young-Ah Moon et al.   JOURNAL OF LIPID RESEARCH

Update of the LIPID MAPS comprehensive classification system for lipids

(2008) Eoin Fahy et al.   JOURNAL OF LIPID RESEARCH

Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes

(2008) Deborah M. Muoio et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sources of hepatic triglyceride accumulation during high-fat feeding in the healthy rat

(2008) T. C. Delgado et al.   NMR IN BIOMEDICINE