The multiple roles of the CD8 coreceptor in T cell biology: opportunities for the selective modulation of self-reactive cytotoxic T cells

The T Cell Receptor's  -Chain Connecting Peptide Motif Promotes Close Approximation of the CD8 Coreceptor Allowing Efficient Signal Initiation

(2014) M. Mallaun et al.   JOURNAL OF IMMUNOLOGY

Late Arrival: Recruiting Coreceptors to the T Cell Receptor Complex

(2011) P. Anton van der Merwe et al.   IMMUNITY

Two-Stage Cooperative T Cell Receptor-Peptide Major Histocompatibility Complex-CD8 Trimolecular Interactions Amplify Antigen Discrimination

(2011) Ning Jiang et al.   IMMUNITY

Opposite Effects of Endogenous Peptide-MHC Class I on T Cell Activity in the Presence and Absence of CD8

(2011) J. D. Stone et al.   JOURNAL OF IMMUNOLOGY

Anti-CD8 Antibodies Can Trigger CD8+ T Cell Effector Function in the Absence of TCR Engagement and Improve Peptide-MHCI Tetramer Staining

(2011) M. Clement et al.   JOURNAL OF IMMUNOLOGY

New insights into T cell biology and T cell-directed therapy for autoimmunity, inflammation, and immunosuppression

(2010) Scott M. Steward-Tharp et al.   Annals of the New York Academy of Sciences

A Galectin-3 Ligand Corrects the Impaired Function of Human CD4 and CD8 Tumor-Infiltrating Lymphocytes and Favors Tumor Rejection in Mice

(2010) N. Demotte et al.   CANCER RESEARCH

Anti-inflammatory Agents: Present and Future

(2010) Charles A. Dinarello   CELL

CD8 Controls T Cell Cross-Reactivity

(2010) L. Wooldridge et al.   JOURNAL OF IMMUNOLOGY

Modification of MHC Anchor Residues Generates Heteroclitic Peptides That Alter TCR Binding and T Cell Recognition

(2010) D. K. Cole et al.   JOURNAL OF IMMUNOLOGY

CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery

(2010) M. N. Artyomov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathogenic CD8+T cells in multiple sclerosis

(2009) Manuel A. Friese et al.   ANNALS OF NEUROLOGY

T Cell Activation

(2009) Jennifer E. Smith-Garvin et al.   Annual Review of Immunology

Structural Basis of the CD8  /MHC Class I Interaction: Focused Recognition Orients CD8  to a T Cell Proximal Position

(2009) R. Wang et al.   JOURNAL OF IMMUNOLOGY

Autoimmune Destruction of Skin Melanocytes by Perilesional T Cells from Vitiligo Patients

(2009) Jasper G. van den Boorn et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

CD4 and CD8: an inside-out coreceptor model for innate immune cells

(2009) Derrick Gibbings et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The primacy of CD8 T lymphocytes in type 1 diabetes and implications for therapies

(2009) Denise L. Faustman et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Emerging multiple sclerosis oral therapies

(2009) K. W. Rammohan et al.   NEUROLOGY

CD8+T-cells and their interaction with other cells in damage to islet β-cells

(2008) F. Susan Wong et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Restoring the Association of the T Cell Receptor with CD8 Reverses Anergy in Human Tumor-Infiltrating Lymphocytes

(2008) Nathalie Demotte et al.   IMMUNITY

Homeostasis of Naive and Memory T Cells

(2008) Charles D. Surh et al.   IMMUNITY

Interferon-  and interleukin-4 reciprocally regulate CD8 expression in CD8+ T cells

(2008) S. H. Apte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA