New Virulence Determinants Contribute to the Enhanced Immune Response and Reduced Virulence of an Influenza A Virus A/PR8/34 Variant

CCR2+ Monocyte-Derived Dendritic Cells and Exudate Macrophages Produce Influenza-Induced Pulmonary Immune Pathology and Mortality

(2014) K. L. Lin et al.   JOURNAL OF IMMUNOLOGY

A Single Point Mutation (Y89F) within the Non-Structural Protein 1 of Influenza A Viruses Limits Epithelial Cell Tropism and Virulence in Mice

(2012) Eike R. Hrincius et al.   AMERICAN JOURNAL OF PATHOLOGY

Phosphatidylinositol-3-kinase (PI3K) is activated by influenza virus vRNA via the pathogen pattern receptor Rig-I to promote efficient type I interferon production

(2011) Eike R. Hrincius et al.   CELLULAR MICROBIOLOGY

NS1-mediated delay of type I interferon induction contributes to influenza A virulence in ferrets

(2011) I. Meunier et al.   JOURNAL OF GENERAL VIROLOGY

Synergistic Adaptive Mutations in the Hemagglutinin and Polymerase Acidic Protein Lead to Increased Virulence of Pandemic 2009 H1N1 Influenza A Virus in Mice

(2011) Roman Seyer et al.   JOURNAL OF INFECTIOUS DISEASES

The influenza virus RNA synthesis machine

(2011) Patricia Resa-Infante et al.   RNA Biology

Type I Interferon Signaling Regulates Ly6Chi Monocytes and Neutrophils during Acute Viral Pneumonia in Mice

(2011) Sang-Uk Seo et al.   PLoS Pathogens

The Influenza Virus Protein PB1-F2 Inhibits the Induction of Type I Interferon at the Level of the MAVS Adaptor Protein

(2011) Zsuzsanna T. Varga et al.   PLoS Pathogens

CRK adaptor protein expression is required for efficient replication of avian influenza A viruses and controls JNK-mediated apoptotic responses

(2010) Eike R. Hrincius et al.   CELLULAR MICROBIOLOGY

Influenza A Virus Polymerase Inhibits Type I Interferon Induction by Binding to Interferon β Promoter Stimulator 1

(2010) Atsushi Iwai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Influenza A Virus Polymerase: Structural Insights into Replication and Host Adaptation Mechanisms

(2010) Stéphane Boivin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Strand-specific real-time RT-PCR for distinguishing influenza vRNA, cRNA, and mRNA

(2010) Eiryo Kawakami et al.   JOURNAL OF VIROLOGICAL METHODS

The PB2 Subunit of the Influenza Virus RNA Polymerase Affects Virulence by Interacting with the Mitochondrial Antiviral Signaling Protein and Inhibiting Expression of Beta Interferon

(2010) K. M. Graef et al.   JOURNAL OF VIROLOGY

Influenza Virus Non-Structural Protein 1 (NS1) Disrupts Interferon Signaling

(2010) Danlin Jia et al.   PLoS One

Perspectives on influenza evolution and the role of research

(2010) Heather L. Forrest et al.   ANIMAL HEALTH RESEARCH REVIEWS

Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I

(2009) Michaela Ulrike Gack et al.   Cell Host & Microbe

The Alpha/Beta Interferon Receptor Provides Protection against Influenza Virus Replication but Is Dispensable for Inflammatory Response Signaling

(2009) A. G. Goodman et al.   JOURNAL OF VIROLOGY

Early Control of H5N1 Influenza Virus Replication by the Type I Interferon Response in Mice

(2009) K. J. Szretter et al.   JOURNAL OF VIROLOGY

Host Genetic Background Strongly Influences the Response to Influenza A Virus Infections

(2009) Barkha Srivastava et al.   PLoS One

The Pathology of Influenza Virus Infections

(2008) Jeffery K. Taubenberger et al.   Annual Review of Pathology-Mechanisms of Disease

Lung epithelial apoptosis in influenza virus pneumonia: the role of macrophage-expressed TNF-related apoptosis-inducing ligand

(2008) Susanne Herold et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The multifunctional NS1 protein of influenza A viruses

(2008) B. G. Hale et al.   JOURNAL OF GENERAL VIROLOGY