NS1-mediated delay of type I interferon induction contributes to influenza A virulence in ferrets

Pathogenicity of different PR8 influenza A virus variants in mice is determined by both viral and host factors

(2011) Paulina Blazejewska et al.   VIROLOGY

Inefficient Control of Host Gene Expression by the 2009 Pandemic H1N1 Influenza A Virus NS1 Protein

(2010) B. G. Hale et al.   JOURNAL OF VIROLOGY

Influenza A virus strains that circulate in humans differ in the ability of their NS1 proteins to block the activation of IRF3 and interferon-β transcription

(2010) Rei-Lin Kuo et al.   VIROLOGY

Structure-based design of NS2 mutants for attenuated influenza A virus vaccines

(2010) Hatice Akarsu et al.   VIRUS RESEARCH

Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I

(2009) Michaela Ulrike Gack et al.   Cell Host & Microbe

Human Infection with Highly Pathogenic Avian Influenza A (H5N1) Virus: Review of Clinical Issues

(2009) Timothy M. Uyeki   CLINICAL INFECTIOUS DISEASES

NS2/NEP protein regulates transcription and replication of the influenza virus RNA genome

(2009) Nicole C. Robb et al.   JOURNAL OF GENERAL VIROLOGY

Innate immune control and regulation of influenza virus infections

(2009) Jodi McGill et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The NS1 Protein of the 1918 Pandemic Influenza Virus Blocks Host Interferon and Lipid Metabolism Pathways

(2009) R. Billharz et al.   JOURNAL OF VIROLOGY

The NS1 Protein of a Human Influenza Virus Inhibits Type I Interferon Production and the Induction of Antiviral Responses in Primary Human Dendritic and Respiratory Epithelial Cells

(2009) K. Haye et al.   JOURNAL OF VIROLOGY

Progress in identifying virulence determinants of the 1918 H1N1 and the Southeast Asian H5N1 influenza A viruses

(2008) Christopher F. Basler et al.   ANTIVIRAL RESEARCH

Gene Expression Analysis of Host Innate Immune Responses during Lethal H5N1 Infection in Ferrets

(2008) C. M. Cameron et al.   JOURNAL OF VIROLOGY

Structural basis for suppression of a host antiviral response by influenza A virus

(2008) K. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new influenza virus virulence determinant: The NS1 protein four C-terminal residues modulate pathogenicity

(2008) D. Jackson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus

(2008) C. Pappas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viral RNA polymerase complex promotes optimal growth of 1918 virus in the lower respiratory tract of ferrets

(2008) T. Watanabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Severe seasonal influenza in ferrets correlates with reduced interferon and increased IL-6 induction

(2008) Nicholas Svitek et al.   VIROLOGY

Multiple Reassortment Events in the Evolutionary History of H1N1 Influenza A Virus Since 1918

(2008) Martha I. Nelson et al.   PLoS Pathogens

H5N1 and 1918 Pandemic Influenza Virus Infection Results in Early and Excessive Infiltration of Macrophages and Neutrophils in the Lungs of Mice

(2008) Lucy A. Perrone et al.   PLoS Pathogens

Cloning, expression and characterization of ferret CXCL10

(2007) Ali Danesh et al.   MOLECULAR IMMUNOLOGY