Function of MbtH homologs in nonribosomal peptide biosynthesis and applications in secondary metabolite discovery

Strain improvement in actinomycetes in the postgenomic era

(2011) Richard H. Baltz   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Genetically Engineered Lipopeptide Antibiotics Related to A54145 and Daptomycin with Improved Properties

(2010) K. T. Nguyen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Development of a Genetic System for Combinatorial Biosynthesis of Lipopeptides in Streptomyces fradiae and Heterologous Expression of the A54145 Biosynthesis Gene Cluster

(2010) D. C. Alexander et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Strain Improvement of Streptomyces roseosporus for Daptomycin Production by Rational Screening of He–Ne Laser and NTG Induced Mutants and Kinetic Modeling

(2010) Guanghai Yu et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Activation of the Pacidamycin PacL Adenylation Domain by MbtH-like Proteins

(2010) Wenjun Zhang et al.   BIOCHEMISTRY

MbtH-Like Proteins as Integral Components of Bacterial Nonribosomal Peptide Synthetases

(2010) Elizabeth A. Felnagle et al.   BIOCHEMISTRY

Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism

(2010) Wei Zhao et al.   CELL RESEARCH

N-Acylation during Glidobactin Biosynthesis by the Tridomain Nonribosomal Peptide Synthetase Module GlbF

(2010) Heidi J. Imker et al.   CHEMISTRY & BIOLOGY

The Sequence of a 1.8-Mb Bacterial Linear Plasmid Reveals a Rich Evolutionary Reservoir of Secondary Metabolic Pathways

(2010) Marnix H. Medema et al.   Genome Biology and Evolution

Production of novel lipopeptide antibiotics related to A54145 by Streptomyces fradiae mutants blocked in biosynthesis of modified amino acids and assignment of lptJ, lptK and lptL gene functions

(2010) Dylan C Alexander et al.   JOURNAL OF ANTIBIOTICS

Genomics and the ancient origins of the daptomycin biosynthetic gene cluster

(2010) Richard H Baltz   JOURNAL OF ANTIBIOTICS

Streptomyces and Saccharopolyspora hosts for heterologous expression of secondary metabolite gene clusters

(2010) Richard H. Baltz   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Identification of the biosynthetic gene cluster for the pacidamycin group of peptidyl nucleoside antibiotics

(2010) W. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solution structure of Rv2377c-founding member of the MbtH-like protein family

(2010) Garry W. Buchko et al.   TUBERCULOSIS

Strategies for the Discovery of New Natural Products by Genome Mining

(2009) Malek Zerikly et al.   CHEMBIOCHEM

Genomic islands link secondary metabolism to functional adaptation in marine Actinobacteria

(2009) Kevin Penn et al.   ISME Journal

Enzymatic Production of (−)-Indolactam V by LtxB, a Cytochrome P450 Monooxygenase

(2009) Minh U. Huynh et al.   JOURNAL OF NATURAL PRODUCTS

Enzymatic Tailoring of Ornithine in the Biosynthesis of theRhizobiumCyclic Trihydroxamate Siderophore Vicibactin

(2009) John R. Heemstra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New natural product biosynthetic chemistry discovered by genome mining

(2009) Christophe Corre et al.   NATURAL PRODUCT REPORTS

Renaissance in antibacterial discovery from actinomycetes

(2008) R BALTZ   CURRENT OPINION IN PHARMACOLOGY

Genome Sequence of the Streptomycin-Producing Microorganism Streptomyces griseus IFO 13350

(2008) Y. Ohnishi et al.   JOURNAL OF BACTERIOLOGY

Trends in Prokaryotic Evolution Revealed by Comparison of Closely Related Bacterial and Archaeal Genomes

(2008) P. S. Novichkov et al.   JOURNAL OF BACTERIOLOGY

Mining microbial genomes for new natural products and biosynthetic pathways

(2008) G. L. Challis   MICROBIOLOGY-SGM