Type 1 IFN and PD-L1 Coordinate Lymphatic Endothelial Cell Expansion and Contraction during an Inflammatory Immune Response

Organ-specific lymphatic vasculature: From development to pathophysiology

(2017) Tatiana V. Petrova et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type I Interferon in Chronic Virus Infection and Cancer

(2017) Laura M. Snell et al.   TRENDS IN IMMUNOLOGY

Migratory dendritic cells acquire and present lymphatic endothelial cell-archived antigens during lymph node contraction

(2017) Ross M. Kedl et al.   Nature Communications

PDL1 Signals through Conserved Sequence Motifs to Overcome Interferon-Mediated Cytotoxicity

(2017) Maria Gato-Cañas et al.   Cell Reports

Lymphatic Vessels Balance Viral Dissemination and Immune Activation following Cutaneous Viral Infection

(2017) Christopher P. Loo et al.   Cell Reports

Tumor-Associated Lymphatic Vessels Upregulate PDL1 to Inhibit T-Cell Activation

(2017) Lothar C. Dieterich et al.   Frontiers in Immunology

Immune-Mediated Protection and Pathogenesis of Chikungunya Virus

(2016) Julie M. Fox et al.   JOURNAL OF IMMUNOLOGY

Platelet-derived CXCL4 regulates neutrophil infiltration and tissue damage in severe acute pancreatitis

(2016) Erik Wetterholm et al.   Translational Research

Potential Role of JAK-STAT Signaling Pathway in the Neurogenic-to-Gliogenic Shift in Down Syndrome Brain

(2016) Han-Chung Lee et al.   NEURAL PLASTICITY

Antigen archiving by lymph node stroma: A novel function for the lymphatic endothelium

(2015) Ross M. Kedl et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

GDF10 is a signal for axonal sprouting and functional recovery after stroke

(2015) Songlin Li et al.   NATURE NEUROSCIENCE

T-cell exhaustion in chronic hepatitis B infection: current knowledge and clinical significance

(2015) B Ye et al.   Cell Death & Disease

Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction

(2015) Sherin J. Rouhani et al.   Nature Communications

Viral Infection of Human Lung Macrophages Increases PDL1 Expression via IFNβ

(2015) Karl J. Staples et al.   PLoS One

A Transgenic Prox1-Cre-tdTomato Reporter Mouse for Lymphatic Vessel Research

(2015) Roberta Bianchi et al.   PLoS One

Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks

(2014) King-Hwa Ling et al.   BMC GENOMICS

Cyclooxygenase-2–dependent lymphangiogenesis promotes nodal metastasis of postpartum breast cancer

(2014) Traci R. Lyons et al.   JOURNAL OF CLINICAL INVESTIGATION

Lymph node stromal cells acquire peptide–MHCII complexes from dendritic cells and induce antigen-specific CD4+T cell tolerance

(2014) Juan Dubrot et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Re-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type I interferons

(2014) Eric M. Pietras et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MicroRNA-513 Regulates B7-H1 Translation and Is Involved in IFN- -Induced B7-H1 Expression in Cholangiocytes

(2014) A.-Y. Gong et al.   JOURNAL OF IMMUNOLOGY

Steady-State Antigen Scavenging, Cross-Presentation, and CD8+ T Cell Priming: A New Role for Lymphatic Endothelial Cells

(2014) S. Hirosue et al.   JOURNAL OF IMMUNOLOGY

Attenuation of IFN-γ-induced B7-H1 expression by 15-deoxy-delta12,14-prostaglandin J2 via downregulation of the Jak/STAT/IRF-1 signaling pathway

(2014) Su-Kil Seo et al.   LIFE SCIENCES

Dendritic cells control fibroblastic reticular network tension and lymph node expansion

(2014) Sophie E. Acton et al.   NATURE

The CLEC-2–podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture

(2014) Jillian L Astarita et al.   NATURE IMMUNOLOGY

Tolerogenic Properties of Lymphatic Endothelial Cells Are Controlled by the Lymph Node Microenvironment

(2014) Jarish N. Cohen et al.   PLoS One

Antigen capture and archiving by lymphatic endothelial cells following vaccination or viral infection

(2014) Beth A. Tamburini et al.   Nature Communications

Lymph node stromal cells constrain immunity via MHC class II self-antigen presentation

(2014) Antonio P Baptista et al.   eLife

VEGFR-3 Neutralization Inhibits Ovarian Lymphangiogenesis, Follicle Maturation, and Murine Pregnancy

(2013) Joseph M. Rutkowski et al.   AMERICAN JOURNAL OF PATHOLOGY

Neutrophils contribute to inflammatory lymphangiogenesis by increasing VEGF-A bioavailability and secreting VEGF-D

(2013) K. W. Tan et al.   BLOOD

Initial Afferent Lymphatic Vessels Controlling Outbound Leukocyte Traffic from Skin to Lymph Nodes

(2013) Alvaro Teijeira et al.   Frontiers in Immunology

Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells

(2012) E. F. Tewalt et al.   BLOOD

Expansion of Cortical and Medullary Sinuses Restrains Lymph Node Hypertrophy during Prolonged Inflammation

(2012) K. W. Tan et al.   JOURNAL OF IMMUNOLOGY

VEGF-C Promotes Immune Tolerance in B16 Melanomas and Cross-Presentation of Tumor Antigen by Lymph Node Lymphatics

(2012) Amanda W. Lund et al.   Cell Reports

A Novel Function for Programmed Death Ligand-1

(2011) Yiping Jin et al.   AMERICAN JOURNAL OF PATHOLOGY

T Lymphocytes Negatively Regulate Lymph Node Lymphatic Vessel Formation

(2011) Raghu P. Kataru et al.   IMMUNITY

Coordinated Regulation of Lymph Node Vascular-Stromal Growth First by CD11c+ Cells and Then by T and B Cells

(2011) S. Chyou et al.   JOURNAL OF IMMUNOLOGY

Endothelial  1 integrins regulate sprouting and network formation during vascular development

(2010) D. Malan et al.   DEVELOPMENT

Lymph node–resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation

(2010) Jarish N. Cohen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflamed Lymphatic Endothelium Suppresses Dendritic Cell Maturation and Function via Mac-1/ICAM-1-Dependent Mechanism

(2009) S. Podgrabinska et al.   JOURNAL OF IMMUNOLOGY

Multiple innate signaling pathways cooperate with CD40 to induce potent, CD70-dependent cellular immunity

(2009) Jennifer A. McWilliams et al.   VACCINE

TLR3: Interferon induction by double-stranded RNA including poly(I:C)☆

(2008) M MATSUMOTO et al.   ADVANCED DRUG DELIVERY REVIEWS

B7-H1 is a ubiquitous antiapoptotic receptor on cancer cells

(2008) T. Azuma et al.   BLOOD

The Immunological Genome Project: networks of gene expression in immune cells

(2008) Tracy S P Heng et al.   NATURE IMMUNOLOGY