Synthesis and evaluation of cationic norbornanes as peptidomimetic antibacterial agents

A new antibiotic kills pathogens without detectable resistance

(2015) Losee L. Ling et al.   NATURE

Synthesis of norbornane bisether antibiotics via silver-mediated alkylation

(2015) Shane M. Hickey et al.   RSC Advances

Facile Synthesis of Guanidine Functionalised Building Blocks

(2015) Shane M. Hickey et al.   Asian Journal of Organic Chemistry

Collateral damage

(2014) Robert E W Hancock   NATURE BIOTECHNOLOGY

Organogelators based on the norbornane scaffold

(2014) Shane M. Hickey et al.   SUPRAMOLECULAR CHEMISTRY

Polymyxins and Analogues Bind to Ribosomal RNA and Interfere with Eukaryotic Translation in Vitro

(2013) Lisa S. McCoy et al.   CHEMBIOCHEM

Conformationally preorganised hosts for anions using norbornane and fused [n]polynorbornane frameworks

(2013) Adam J. Lowe et al.   CHEMICAL COMMUNICATIONS

Antibiotics in the clinical pipeline in 2013

(2013) Mark S Butler et al.   JOURNAL OF ANTIBIOTICS

Prospects for new antibiotics: a molecule-centered perspective

(2013) Christopher T Walsh et al.   JOURNAL OF ANTIBIOTICS

The synthesis of fluorinated endcaps: Part 1. The effect of C-7 fluorination on the base-catalyzed monohydrolysis of 5-norbornenyl-2,3-diesters

(2013) David E. Rajsfus et al.   JOURNAL OF FLUORINE CHEMISTRY

Antimicrobial toxicity studies of ionic liquids leading to a ‘hit’ MRSA selective antibacterial imidazolium salt

(2012) Deborah Coleman et al.   GREEN CHEMISTRY

Squaramides: physical properties, synthesis and applications

(2011) R. Ian Storer et al.   CHEMICAL SOCIETY REVIEWS

New Insights into Cyclobutenone Rearrangements: A Total Synthesis of the Natural ROS-Generating Anti-Cancer Agent Cribrostatin 6

(2011) Mubina Mohamed et al.   CHEMISTRY-A EUROPEAN JOURNAL

Fix the antibiotics pipeline

(2011) Matthew A. Cooper et al.   NATURE

Expeditious preparation of isoxazoles from Δ2-isoxazolines as advanced intermediates for functional materials

(2011) Guilherme D. Vilela et al.   TETRAHEDRON LETTERS

Developing an anion host for lipid A binding and antibacterial activity

(2010) Luke C. Henderson et al.   CHEMICAL COMMUNICATIONS

Antimicrobial peptides: General overview and clinical implications in human health and disease

(2010) Eduardo Guaní-Guerra et al.   CLINICAL IMMUNOLOGY

Antimicrobial Susceptibility Testing: A Review of General Principles and Contemporary Practices

(2009) James H. Jorgensen et al.   CLINICAL INFECTIOUS DISEASES

Structure−Activity Relationships of Polymyxin Antibiotics

(2009) Tony Velkov et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rationally Improved Chiral Brønsted Acid for Catalytic Enantioselective Allylboration of Aldehydes with an Expanded Reagent Scope

(2009) Vivek Rauniyar et al.   JOURNAL OF ORGANIC CHEMISTRY

Stereoselective One-Step Construction of Vicinal Quaternary and Tertiary Stereocenters of the 5,10b-Ethanophenanthridine Skeleton: Total Synthesis of (±)-Maritidine

(2009) Ganesh Pandey et al.   ORGANIC LETTERS

Size matters—strong binding of the terephthalate dianion by thiourea functionalised fused [n]polynorbornane hosts

(2008) Adam J. Lowe et al.   CHEMICAL COMMUNICATIONS

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Factors Influencing Anion Binding Stoichiometry: The Subtle Influence of Electronic Effects

(2008) Adam J. Lowe et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Colistin hetero-resistance in multidrug-resistant Acinetobacter baumannii clinical isolates from the Western Pacific region in the SENTRY antimicrobial surveillance programme

(2008) Wing Yau et al.   JOURNAL OF INFECTION

The Bacteria Fight Back

(2008) G. Taubes   SCIENCE