N-heterocyclic carbene-catalyzed cyclocondensation of 2-aryl carboxylic acids and enones: highly enantioselective synthesis of δ-lactones

On the Mechanism of N-Heterocyclic Carbene-Catalyzed Reactions Involving Acyl Azoliums

(2014) Jessada Mahatthananchai et al.   ACCOUNTS OF CHEMICAL RESEARCH

N-Heterocyclic Carbene Catalyzed Cyclocondensation of α,β-Unsaturated Carboxylic Acids: Enantioselective Synthesis of Pyrrolidinone and Dihydropyridinone Derivatives

(2014) Xiang-Yu Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Isothiourea-Catalyzed Asymmetric Synthesis of β-Lactams and β-Amino Esters from Arylacetic Acid Derivatives and N-Sulfonylaldimines

(2014) Siobhan R. Smith et al.   JOURNAL OF ORGANIC CHEMISTRY

Isothiourea-Mediated Asymmetric Functionalization of 3-Alkenoic Acids

(2014) Louis C. Morrill et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Annulations for Dihydroquinolones by in Situ Generation of Azolium Enolates

(2014) Anna Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric NHC-Catalyzed Aza-Diels–Alder Reactions: Highly Enantioselective Route to α-Amino Acid Derivatives and DFT Calculations

(2014) Limin Yang et al.   ORGANIC LETTERS

Catalytic Asymmetric α-Aldol Reaction of Vinylogous N-Heterocyclic Carbene Enolates: Formation of Quaternary and Labile Tertiary Stereocenters

(2014) Xiuqin Dong et al.   ORGANIC LETTERS

Bifunctional N-Heterocyclic Carbene-Catalyzed Highly Enantioselective Synthesis of Spirocyclic Oxindolo-β-lactams

(2014) Han-Ming Zhang et al.   ORGANIC LETTERS

Asymmetric Synthesis of Tri- and Tetrasubstituted Trifluoromethyl Dihydropyranones from α-Aroyloxyaldehydes via NHC Redox Catalysis

(2014) Alyn T. Davies et al.   ACS Catalysis

Asymmetric Synthesis of Pyrroloindolones by N-Heterocyclic Carbene Catalyzed [2+3] Annulation of α-Chloroaldehydes with Nitrovinylindoles

(2013) Qijian Ni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Acyl anion free N-heterocyclic carbene organocatalysis

(2013) Sarah J. Ryan et al.   CHEMICAL SOCIETY REVIEWS

Stereospecific Asymmetric N-Heterocyclic Carbene (NHC)-Catalyzed Redox Synthesis of Trifluoromethyl Dihydropyranones and Mechanistic Insights

(2013) Alyn T. Davies et al.   JOURNAL OF ORGANIC CHEMISTRY

An internal affair

(2013) Jeffrey W. Bode   Nature Chemistry

N-Heterocyclic carbene-catalyzed highly enantioselective synthesis of substituted dihydropyranopyrazolones

(2013) Han-Ming Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Organocatalytic Activation of Alkylacetic Esters as Enolate Precursors to React with α,β-Unsaturated Imines

(2013) Lin Hao et al.   ORGANIC LETTERS

Asymmetric NHC-Catalyzed Redox α-Amination of α-Aroyloxyaldehydes

(2013) James E. Taylor et al.   ORGANIC LETTERS

Asymmetric Access to the Smallest Enolate Intermediate via Organocatalytic Activation of Acetic Ester

(2013) Shaojin Chen et al.   ORGANIC LETTERS

Palladium-Catalyzed β-Arylation of Silyl Ketene Acetals and Application to the Synthesis of Benzo-Fused δ-Lactones

(2013) Sam Aspin et al.   ORGANIC LETTERS

Quantitative analysis of γ- and δ-lactones in wines using gas chromatography with selective tandem mass spectrometric detection

(2013) Johannes Langen et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Isothiourea-mediated asymmetric Michael-lactonisation of trifluoromethylenones: a synthetic and mechanistic study

(2013) Louis C. Morrill et al.   Chemical Science

Exploiting Acyl and Enol Azolium Intermediates via N-Hetero- cyclic Carbene-Catalyzed Reactions of α-Reducible Aldehydes

(2012) Harit U. Vora et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective Synthesis of β,γ-Unsaturated α-Fluoroesters Catalyzed by N-Heterocyclic Carbenes

(2012) Yu-Ming Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dihydropyridones: Catalytic Asymmetric Synthesis, N- to C-Sulfonyl Transfer, and Derivatizations

(2012) Carmen Simal et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Continuum of Progress: Applications of N-Hetereocyclic Carbene Catalysis in Total Synthesis

(2012) Javier Izquierdo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly enantioselective [4 + 2] cyclization of chloroaldehydes and 1-azadienes catalyzed by N-heterocyclic carbenes

(2012) Teng-Yue Jian et al.   CHEMICAL COMMUNICATIONS

Organocatalytic umpolung: N-heterocyclic carbenes and beyond

(2012) Xavier Bugaut et al.   CHEMICAL SOCIETY REVIEWS

Enantioselective Activation of Stable Carboxylate Esters as Enolate Equivalents via N-Heterocyclic Carbene Catalysts

(2012) Lin Hao et al.   ORGANIC LETTERS

N-Heterocyclic Carbene (NHC)-Catalyzed Highly Diastereo- and Enantioselective Oxo-Diels–Alder Reactions for Synthesis of Fused Pyrano[2,3-b]indoles

(2012) Limin Yang et al.   ORGANIC LETTERS

Catalytic asymmetric α-amination of carboxylic acids using isothioureas

(2012) Louis C. Morrill et al.   Chemical Science

A Highly Regio- and Stereoselective Cascade Annulation of Enals and Benzodi(enone)s Catalyzed by N-Heterocyclic Carbenes

(2011) Xinqiang Fang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene Catalyzed Domino Reactions

(2011) André Grossmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Functionalization of Carboxylic Acids: Isothiourea-Catalyzed Asymmetric Intra- and Intermolecular Michael Addition−Lactonizations

(2011) Dorine Belmessieri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Diels–Alder Reactions of Enals and Alkylidene Diketones Catalyzed by N-Heterocyclic Carbenes

(2011) Xinqiang Fang et al.   ORGANIC LETTERS

Formal Diels–Alder Reactions of Chalcones and Formylcyclopropanes Catalyzed by Chiral N-Heterocyclic Carbenes

(2011) Hui Lv et al.   ORGANIC LETTERS

Enantioselective, Organocatalyzed, Intramolecular Aldol Lactonizations with Keto Acids Leading to Bi- and Tricyclic β-Lactones and Topology-Morphing Transformations

(2010) Carolyn A. Leverett et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Indole-Fused Dihydropyranones via Catalytic Cycloaddition of Ketenes and 3-Alkylenyloxindoles

(2010) Hui Lv et al.   JOURNAL OF ORGANIC CHEMISTRY

Bioinspired Total Synthesis and Human Proteasome Inhibitory Activity of (−)-Salinosporamide A, (−)-Homosalinosporamide A, and Derivatives Obtained via Organonucleophile Promoted Bis-cyclizations

(2010) Henry Nguyen et al.   JOURNAL OF ORGANIC CHEMISTRY

CooperativeN-Heterocyclic Carbene/Lewis Acid Catalysis for Highly Stereoselective Annulation Reactions with Homoenolates

(2010) Benoit Cardinal-David et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral N-heterocyclic carbene-catalyzed generation of ester enolate equivalents from  , -unsaturated aldehydes for enantioselective Diels-Alder reactions

(2010) J. Kaeobamrung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enantioselective Synthesis of DihydrocoumarinsviaN-Heterocyclic Carbene-Catalyzed Cycloaddition of Ketenes ando-Quinone Methides

(2009) Hui Lv et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Dimerization of Disubstituted Ketenes Catalyzed by N-Heterocyclic Carbenes

(2008) Hui Lv et al.   ADVANCED SYNTHESIS & CATALYSIS

[4+2] Cycloaddition of Ketenes withN-Benzoyldiazenes Catalyzed by N-Heterocyclic Carbenes

(2008) Xue-Liang Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

ChiralN-Heterocyclic Carbene-Catalyzed Formal [4+2] Cycloaddition of Ketenes with Enones: Highly Enantioselective Synthesis oftrans- andcis-δ-Lactones

(2008) Yan-Rong Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Formal Cycloaddition of Disubstituted Ketenes with 2-Oxoaldehydes Catalyzed by Chiral N-Heterocyclic Carbenes

(2008) Lin He et al.   JOURNAL OF ORGANIC CHEMISTRY

Concise Synthesis of Spirocyclic, Bridged γ-Butyrolactones via Stereospecific, Dyotropic Rearrangements of β-Lactones Involving 1,2-Acyl and δ-Lactone Migrations

(2008) Vikram C. Purohit et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric esterification of ketenes catalyzed by an N-heterocyclic carbene

(2008) Xiao-Na Wang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Chiral NHC-Catalyzed Oxodiene Diels−Alder Reactions with α-Chloroaldehyde Bisulfite Salts

(2008) Ming He et al.   ORGANIC LETTERS

Synthesis of enantiopure triazolium salts from pyroglutamic acid and their evaluation in the benzoin condensation

(2008) Dieter Enders et al.   TETRAHEDRON-ASYMMETRY

Chiral N-Heterocyclic Carbene Catalyzed Staudinger Reaction of Ketenes with Imines:  Highly Enantioselective Synthesis ofN-Boc β-Lactams

(2007) Yan-Rong Zhang et al.   ORGANIC LETTERS