Article
Plant Sciences
Anja Roediger, Birgit Agne, Dirk Dobritzsch, Stefan Helm, Fraenze Mueller, Nina Poetzsch, Sacha Baginsky
Summary: In the process of bell pepper (Capsicum annuum) fruit ripening, the conversion from chloroplasts to chromoplasts involves significant changes in the levels of various enzymes, including maintenance of high levels of specific complexes and enzymes, an increase in enzymes related to heterotrophic plastid metabolism, and a shift in abundance of enzymes related to chlorophyll catabolism and carotenoid biosynthesis. Despite these changes, certain proteins remain constant, suggesting a unique metabolic pathway in non-climacteric fruits like bell pepper.
Article
Food Science & Technology
Abiola Owoyemi, Victor Rodov, Ron Porat
Summary: The study found that compostable modified atmosphere packages with different perforation rates had significant effects on preserving red bell pepper quality, with micro-perforated and macro-perforated compostable packages showing the best results. In contrast, nonperforated compostable packages negatively impacted produce quality.
FOOD SCIENCE & NUTRITION
(2021)
Article
Biochemistry & Molecular Biology
Mi-Jin Oh, Hye-Bin Lee, Guijae Yoo, Miri Park, Chang-Hyun Lee, Inwook Choi, Ho-Young Park
Summary: The study evaluated the anti-obesity effect of water-soluble red pepper leaf extract on adipocytes and HFD-fed mice. The findings showed that the extract reduced fat accumulation and improved intestinal health, suggesting its potential in preventing obesity.
Article
Biotechnology & Applied Microbiology
Lixue Liu, Luyao Ma, Jinsong Feng, Xiaonan Lu
Summary: This study used amplicon sequencing to explore the microbiome composition in bell pepper plants and the fluctuation of fungal pathogens across the growing seasons. It was found that the fungal pathogens infecting fruits and leaves of bell pepper plants belonged to various genera. The dominant fungal pathogens changed with the development of the plants. The fungal pathogens decreased species richness and diversity in infected tissues but not in uninfected stem tissues. The study also revealed the competitive interaction between fungal and bacterial communities and the origin of the fungal pathogens.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2022)
Article
Food Science & Technology
Katarzyna Rybak, Artur Wiktor, Dorota Witrowa-Rajchert, Oleksii Parniakov, Malgorzata Nowacka
Summary: Previous literature has shown that using PEF or a combination of PEF and US can improve the dehydration process and enhance the quality of dried products. Different treatments were applied to red bell peppers before freeze-drying, and all analyzed technological variants improved drying kinetics. Non-thermal pretreatment before freeze-drying resulted in higher levels of vitamin C, total phenolic, and carotenoids compared to blanching, despite blanching reducing drying time the most.
Article
Food Science & Technology
Katarzyna Rybak, Artur Wiktor, Katarzyna Pobiega, Dorota Witrowa-Rajchert, Malgorzata Nowacka
Summary: The study shows that pulsed light treatment can maintain the bioactive compounds in red bell pepper fresh-cuts during storage and increase free radical scavenging activity. At a certain fluence level, pulsed light effectively reduces the microbial count, especially being more sensitive to yeasts and molds. Additionally, pulsed light treatment can reduce the mobility of water in vacuoles, aiding in minimizing deterioration reactions.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Plant Sciences
Adewale Suraj Bello, Imen Saadaoui, Talaat Ahmed, Helmi Hamdi, Maroua Cherif, Radhouane Ben-Hamadou
Summary: This study investigated the effects of cyanobacteria HVPE and WRB treatments on bell pepper production in a hydroponic system. The results showed that the foliar application of HVPE and WRB significantly improved the growth parameters, yield components, and biochemical composition of bell peppers. Therefore, the use of HVPE and WRB treatments can enhance the production and chemical constituents of bell peppers.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Food Science & Technology
Sera Jung, Hyojun An, Jong-Hee Lee
Summary: Red pepper powder influences the growth of lactic acid bacteria in watery kimchi fermentation, particularly during the first week, leading to higher counts of Lactobacillus and Weissella.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Food Science & Technology
Nishant Kumar, Pratibha, Neeraj, Ankur Ojha, Ashutosh Upadhyay, Rakhi Singh, Shiv Kumar
Summary: The study demonstrated that the composite edible coating of chitosan-pullulan (50:50) enriched with pomegranate peel extract significantly improved the storage quality and shelf life of bell pepper, maintaining its appearance, taste, and antioxidant activity.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Cristina Reche, Carmen Rossello, Valeria Eim, Alberto Edel Leon, Susana Simal
Summary: High-power ultrasound treatment enhances the release of antioxidants and phenolic compounds from red bell pepper during digestion by causing microstructural changes in the plant tissue, such as cell shrinkage and an increased number of cells. This leads to an increase in the bioaccessibility of these bioactive compounds.
Article
Food Science & Technology
Jung Sik Lim, Chae Rim Kim, Kwang Soon Shin, Sue Jung Lee, Taek Joon Yoon, Hee Jung Park
Summary: The study found that the mixture of GABA and GIN can significantly reduce IgE levels, increase OVA-IgG2a antibody production, and have a positive effect on Th1 cytokines. This mixture can also alleviate allergic symptoms and regulate the Th1-Th2 balance.
FOOD SCIENCE AND BIOTECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Mohamad Khatib, Lorenzo Cecchi, Maria Bellumori, Beatrice Zonfrillo, Nadia Mulinacci
Summary: This study aimed to extract valuable bioactive compounds from by-products of basil, tomato, and red bell pepper production. Water and ethanol extraction methods were used, with different temperatures for each sample. The phenolic extracts were analyzed, and the polysaccharides of tomato and red bell pepper were chemically characterized. The study showed that the dry extracts obtained can serve as important sources of bioactive phenols.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Applied
Anbazhagan Sathiyaseelan, Kandasamy Saravanakumar, Arokia Vijay Anand Mariadoss, Chelliah Ramachandran, Xiaowen Hu, Deog-Hwan Oh, Myeong-Hyeon Wang
Summary: The combined treatment of CaCl2-LMWCS/TTO nanoemulsion effectively extends the shelf life of fresh-cut red bell pepper, reduces foodborne pathogenic contamination, and maintains the texture, sensory behavior, and overall quality of the bell peppers.
PROGRESS IN ORGANIC COATINGS
(2021)
Article
Horticulture
Blanca E. Orosco-Alcala, Hector G. Nunez-Palenius, Fidel Diaz-Serrano, Luis Perez-Moreno, Mauricio Valencia-Posadas, Libia I. Trejo-Tellez, Nicacio Cruz-Huerta, Juan I. Valiente-Banuet
Summary: The study showed that grafting the bell pepper 'Viper' cultivar on the salt-tolerant rootstock E21R10144 increased plant tolerance to salinity conditions, promoting plant growth and reducing damage caused by salts to both morphology and physiology.
HORTICULTURE ENVIRONMENT AND BIOTECHNOLOGY
(2021)
Article
Food Science & Technology
Xiaowen Hu, Kandasamy Saravanakumar, Tieyan Jin, Myeong-Hyeon Wang
Summary: The study investigated the biomedical value of red and yellow bell pepper extracts in terms of antioxidant, antibacterial, and anticancer activities through in vitro and virtual studies. The results showed that RME had higher levels of total phenols and total flavonoids, exhibited stronger antibacterial activity, and induced cellular damage in B. cereus biofilm. Additionally, RME demonstrated higher cytotoxicity in human lung cancer cells and potential compounds with higher docking energy against specific enzymes and proteins.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2021)
Review
Biochemistry & Molecular Biology
Dan Liu, Yuezhen Ouyang, Ruoxin Chen, Mingfu Wang, Chao Ai, Hesham R. El-Seedi, Md Moklesur Rahman Sarker, Xinhua Chen, Chao Zhao
Summary: Various theories are constantly proposed to explain the mechanisms of aging, including oxidative stress, DNA dysfunction, inflammation, etc., which lead to the development of various diseases. Ulva polysaccharides have emerged as desirable materials for maintaining health due to their special structures and multiple functions.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Review
Biochemistry & Molecular Biology
Nisa Najibah Mahleyuddin, Said Moshawih, Long Chiau Ming, Hanis Hanum Zulkifly, Nurolaini Kifli, Mei Jun Loy, Md. Moklesur Rahman Sarker, Yaser Mohammed Al-Worafi, Bey Hing Goh, Shobna Thuraisingam, Hui Poh Goh
Summary: Coriandrum sativum is a widely used plant in culinary and traditional medicine, known for its various phytochemicals and their effects such as anticancer, anti-inflammatory, antidiabetic, and analgesic properties. This review evaluates and discusses the effectiveness of C. sativum in cardiovascular diseases based on recent literature, finding that it has antihypertensive, anti-atherogenic, antiarrhythmic, hypolipidemic, and cardioprotective effects.
Article
Public, Environmental & Occupational Health
Md. Jamal Hossain, Foyez Ahmmed, Md. Moklesur Rahman Sarker, Sneha Sarwar, Md. Sazzadul Bari, Md. Robin Khan, Saimon Shahriar, Md. Oliullah Rafi, Talha Bin Emran, Saikat Mitra, Md. Rabiul Islam, Isa Naina Mohamed
Summary: The study evaluated the impact of COVID-19 on Bangladeshi university students' e-Learning activities, severe session jam phobia, and psychological distress, revealing that a majority of students are experiencing mental health issues and session jam phobia.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Biochemistry & Molecular Biology
Nishan Chakrabarty, Hea-Jong Chung, Rashedul Alam, Nazim Uddin Emon, Safaet Alam, Mohammed Fazlul Kabir, Md Minarul Islam, Seong-Tshool Hong, Tapas Sarkar, Md Moklesur Rahman Sarker, Mohammad Manjur Rahman
Summary: This study investigated the hepatoprotective and antioxidant potential of the methanol extract of Gynura nepalensis D.C. The results showed significant hepatoprotective and antioxidant properties. Molecular docking studies revealed certain compounds with high binding affinity.
Article
Biochemistry & Molecular Biology
Prerana B. B. Jadhav, Shailaja B. B. Jadhav, Mehrukh Zehravi, Mohammad S. S. Mubarak, Fahadul Islam, Philippe Jeandet, Sharuk L. L. Khan, Nazmul Hossain, Salma Rashid, Long Chiau Ming, Md. Moklesur Rahman Sarker, Mohd Fahami Nur Azlina
Summary: The aim of this study was to synthesize carbohydrazide derivatives as DPP-IV inhibitors and evaluate their antidiabetic activity. Molecular docking, ADMET analysis, and drug-likeness guidelines were used for simulations. The synthesized compounds showed excellent hypoglycemic potential both in vitro and in vivo, and could be used as leads in developing novel antidiabetic agents.
Article
Biochemistry & Molecular Biology
Pallavi Kishor Vawhal, Shailaja B. Jadhav, Sumit Kaushik, Kahnu Charan Panigrahi, Chandan Nayak, Humaira Urmee, Sharuk L. Khan, Falak A. Siddiqui, Fahadul Islam, Aziz Eftekhari, Abdullah R. Alzahrani, Mohd Fahami Nur Azlina, Md. Moklesur Rahman Sarker, Ibrahim Abdel Aziz Ibrahim
Summary: Recent research has shown that DPP-IV inhibitors can effectively treat type 2 diabetes. This study aimed to develop coumarin-based sulphonamides as potential DPP-IV inhibitors. Among the synthesized compounds, 6i and 6j exhibited the most potent DPP-IV inhibition.
Review
Chemistry, Physical
Arpita Roy, Srijal Kunwar, Utsav Bhusal, Saad Alghamdi, Mazen Almehmadi, Hayaa M. Alhuthali, Mamdouh Allahyani, Md. Jamal Hossain, Md. Abir Hasan, Md. Moklesur Rahman Sarker, Mohd Fahami Nur Azlina
Summary: Nanoparticles less than 100 nm in size have attracted considerable interest in various fields due to their unique physical and chemical characteristics. Trimetallic nanoparticles have shown superior catalytic, biomedical, antimicrobial, active food packaging, and sensing applications compared to monometallic or bimetallic nanoparticles. However, the chemical and physical methods currently used for synthesizing these nanoparticles are expensive and environmentally toxic. This review provides an overview of the synthesis of trimetallic nanoparticles using biological agents and explores their applications in areas such as anticancer, antimicrobial activity, drug delivery, and catalytic activity.
Article
Infectious Diseases
Mohd Sayeed Shaikh, Mayura A. Kale, V. Muralidharan, T. Venkatachalam, Syed Sarfaraz Ali, Fahadul Islam, Sharuk L. Khan, Falak A. Siddiqui, Humaira Urmee, Ganesh G. Tapadiya, Sachin A. Dhawale, Long Chiau Ming, Ibrahim Abdel Aziz Ibrahim, Abdullah R. Alzahrani, Md. Moklesur Rahman Sarker, Mohd Fahami Nur Azlina
Summary: Thiazole and oxazole analogues of diaminopimelic acid (DAP) showed significant antibacterial efficacy, with MICs of 70-80 μg/mL against all tested bacteria. The docking scores revealed that the synthesized compounds interact more precisely with dapF than LL-DAP, suggesting their potential as inhibitors of bacterial cell wall synthesis. The structure-based drug design approach was used to synthesize these compounds.
Article
Food Science & Technology
Jianping Nie, Wei Liao, Zijie Zhang, Minjiao Zhang, Yuxi Wen, Esra Capanoglu, Md Moklesur Rahman Sarker, Ruiyu Zhu, Chao Zhao
Summary: This review introduces a 3D co-culture intestinal organoid system developed from stem cells, which can simulate human tissues and be used for studying glucose metabolism diseases and drug screening. The gut has been identified as an important site for studying the interactions among glucose metabolism, gut microbial metabolism, and gut microbiota. The construction methods and progress of 3D intestinal organoid systems compared to traditional 2D culture methods are also summarized in the manuscript.
CURRENT RESEARCH IN FOOD SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Mehmet Firat Baran, Cumali Keskin, Ayse Baran, Abdulkerim Hatipoglu, Mahmut Yildiztekin, Selcuk Kucukaydin, Kadri Kurt, Hulya Hosgoren, Md. Moklesur Rahman Sarker, Albert Sufianov, Ozal Beylerli, Rovshan Khalilov, Aziz Eftekhari
Summary: This study focuses on the synthesis and characterization of silver nanoparticles (AgNPs) using Allium cepa peel and evaluates their antimicrobial, antioxidant, and anticholinesterase activities. The biosynthesized nanoparticles were characterized using various techniques, and their crystal size and zeta potential were determined. AC-AgNPs showed strong growth inhibitory activities against specific microorganisms, exhibited antioxidant properties, and demonstrated inhibitory effects on key enzymes. Overall, this eco-friendly and cost-effective method has potential applications in biomedicine and industry.
Article
Pharmacology & Pharmacy
Shopnil Akash, Arafat Hossain, Nobendu Mukerjee, Md. Moklesur Rahman Sarker, Mohammad Firoz Khan, Md. Jamal Hossain, Mohammad A. Rashid, Ajoy Kumer, Arabinda Ghosh, Darwin A. Leon-Figueroa, Joshuan J. Barboza, Bijaya Kumar Padhi, Ranjit Sah
Summary: During the second phase of SARS-CoV-2, a black fungus infection called Mucormycosis emerged among hospitalized COVID-19 patients, increasing the death rate. In addition, other pathogenic diseases like Monkeypox and Marburg virus have also impacted global health. Due to their severe pathogenic capabilities and rapid spread, policymakers are concerned about these pathogens. However, there are currently no standard therapies available to manage and treat these conditions.
FRONTIERS IN PHARMACOLOGY
(2023)
Review
Microbiology
Suaidah Ramli, Yuan Seng Wu, Kalaivani Batumalaie, Rhanye Mac Guad, Ker Woon Choy, Ashok Kumar, Subash C. B. Gopinath, Md. Moklesur Rahman Sarker, Vetriselvan Subramaniyan, Mahendran Sekar, Neeraj Kumar Fuloria, Shivkanya Fuloria, Suresh V. Chinni, Gobinath Ramachawolran
Summary: This review focuses on the therapeutic efficacy and molecular mechanisms of Withania somnifera (WS) extracts and their phytochemicals against SARS-CoV-2 infection. It also discusses the use of molecular docking in developing potential inhibitors from WS to target the virus and host cell receptors. Additionally, the review explores the use of nanoformulations or nanocarriers in enhancing WS delivery for improved bioavailability and treatment efficacy.
Review
Multidisciplinary Sciences
S. M. Neamul Kabir Zihad, Nazifa Sifat, Mohammad Ashraful Islam, A. S. M. Monjur-Al-Hossain, K. M. Yasif Kayes Sikdar, Md Moklesur Rahman Sarker, Jamil A. Shilpi, Shaikh Jamal Uddin
Summary: This review summarizes the role of pattern recognition receptors in host immune cells in recognizing Mycobacterium tuberculosis and initiating signaling pathways, providing molecular insight into the interaction between specific Mtb ligands and specific PRRs. This information can aid in identifying novel drug targets and developing new drugs and adjuvants.
Article
Environmental Sciences
Arifa Sultana, Sabiha Rahman Mim, Ananya Saha, Fahmida Yesmin, Md. Rafat Tahsin, Nasiba Binte Bahar, Kazi Rubiya Fatema, Saimon Shahriar, Kazi Milenur Rahman Prattay, Fazle Rabbi, Fabiha Noushin, Mithun Samodder, Qurratul Ain Sadia, Jannatul Ferdous, Md. Ariful Haque Mamun, Mohammad Ikram Uddin, Tahmina Akter, Md. Mustafizur Rahman, Md. Moklesur Rahman Sarker, Md. Ruhul Kuddus, Fahima Aktar, Jakir Ahmed Chowdhury, Abu Asad Chowdhury, Shaila Kabir, Sultan Mehtap Bueyueker, Md. Sohanur Rahman, Md. Habibur Rahman, Md. Shah Amran
Summary: Mass vaccination programs have been effective in reducing the severity of the pandemic, but there have been reports of adverse effects in Turkey and Bangladesh. This study aimed to evaluate the adverse effects of different vaccines in both countries and the population's willingness to continue vaccination despite the side effects. An online survey was conducted from July to December 2021, and the questionnaire was shared with vaccinated individuals in Turkey and Bangladesh. The study found that a significant percentage of respondents experienced side effects, with pain at the injection site being the most common. However, there were no significant adverse events reported after receiving the COVID-19 vaccines in both countries. The vaccines showed similar patterns of efficacy and safety during the study period.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Letter
Pediatrics
Md. Jamal Hossain, Md. Al-Mamun, Morshed Alam, Mst. Rukaia Khatun, Md. Moklesur Rahman Sarker, Md. Rabiul Islam
Summary: Drowning is a major public health concern in Bangladesh, with children being the most vulnerable victims. Risk factors for child drowning deaths include insufficient parental supervision, mother's illiteracy, lack of swimming ability, male gender, children under 5 years, geographical and environmental conditions, seasonality, and disasters. Governments and local administrations are urged to take coordinated and integrated efforts to prevent child drowning deaths.
BMJ PAEDIATRICS OPEN
(2022)
