Article
Fisheries
Jie Ma, Jesse T. Trushenski, Evan M. Jones, Timothy J. Bruce, Doug G. McKenney, Gael Kurath, Kenneth D. Cain
Summary: This study explores the maternal immunity in rainbow trout aquaculture, showing that vaccination of broodstock can reduce mortality in offspring from viral and bacterial diseases.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Microbiology
Maialen Aldabaldetrecu, Mick Parra, Sarita Soto-Aguilera, Pablo Arce, Amaya Paz de la Vega Quiroz, Rodrigo Segura, Mario Tello, Juan Guerrero, Brenda Modak
Summary: The study showed that adding [Cu(NN1)(2)](ClO4) as a dietary supplement to rainbow trout for 15 days at doses of 29 and 58 μg/g fish did not affect growth, but resulted in changes in copper concentration in the intestine and muscle. High copper levels were detected in pond water after feeding with the complex. The administration of [Cu(NN1)(2)](ClO4) at 58 μg/g of fish for 15 days showed a 75% survival rate against F. psychrophilum.
Article
Multidisciplinary Sciences
Mio Takeuchi, Erina Fujiwara-Nagata, Taiki Katayama, Hiroaki Suetake
Summary: Research on manipulating the skin microbiome is important for combating rainbow trout diseases, and using cultivation combined with sequencing helps to identify skin bacteria that can antagonize Flavobacterium psychrophilum.
SCIENTIFIC REPORTS
(2021)
Article
Immunology
Furong Deng, Di Wang, Thomas P. Loch, Fuguang Chen, Tongyan Lu, Yongsheng Cao, Dan Fan, Shaowu Li
Summary: This study utilized RNA-seq analysis to investigate the molecular mechanism of immune response in rainbow trout spleen during Flavobacterium psychrophilum infection. The results revealed key signaling pathways and provided valuable insights for future research on prevention and control of bacterial coldwater disease in salmon culture.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Microbiology
Jiyeon Park, Hyeongjin Roh, Yoonhang Lee, Ju-Yeop Lee, Hyo-Young Kang, Min Ji Seong, Yura Kang, Young Ung Heo, Bo Seong Kim, Chan-Il Park, Do-Hyung Kim
Summary: This study reports the first detection of Flavobacterium psychrophilum in Korea and describes its genotypic and phenotypic characteristics. The study also reveals the pathogenicity and antibiotic resistance of the pathogen and proposes control measures. This is important for understanding the impact of this pathogen on Korean rainbow trout populations and establishing surveillance and control measures to prevent further transmission and outbreaks.
Article
Biology
Moonika H. Marana, Inger Dalsgaard, Per Walter Kania, Abdu Mohamed, Jens Hannibal, Kurt Buchmann
Summary: The study showed that an injection vaccine can reduce the shedding of Flavobacterium psychrophilum from older rainbow trout, increase antibody titers against multiple serotypes, and decrease infection risk at farm level.
Article
Microbiology
Valentina Laura Donati, Lone Madsen, Mathias Middelboe, Mikael Lenz Strube, Inger Dalsgaard
Summary: This study investigated the effects of antibiotics and phage therapies on the gut microbiota of rainbow trout fry, with a focus on the pathogen Flavobacterium psychrophilum. The results showed that both the infection and the administration of antibiotics caused dysbiosis in the fish gut. Additionally, the addition of phages altered the fish microbiota regardless of the presence of the target bacterium. However, there were no observed negative effects on fish health or growth. Further studies should focus on determining the benefits or disadvantages of these changes for fish health and the host immune response.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Immunology
Ali Ali, Mohamed Salem
Summary: This study identified 13,503 long noncoding natural antisense transcripts (lncNATs) in rainbow trout using 134 RNA-Seq datasets. Most of the lncNATs showed strong positive correlation with their corresponding sense transcripts. Differential expression analysis revealed that lncNATs complementary to genes related to immunity, muscle contraction, proteolysis, and iron/heme metabolism were differentially expressed following infection. lncNATs complementary to hepcidin, a master negative regulator of plasma iron concentration, were downregulated in resistant fish on day 5 of bacterial infection.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Fisheries
Furong Deng, Di Wang, Fuguang Chen, Tongyan Lu, Shaowu Li
Summary: This study identified and functionally characterized OmCLDN4L protein in rainbow trout. OmCLDN4L plays a crucial role in the rainbow trout's immune response to bacterial infection and provides new insights into the molecular mechanism of intestinal barrier in rainbow trout against F. psychrophilum infection.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Juan-Ting Liu, Phuc H. Pham, John S. Lumsden
Summary: Feeding rainbow trout with deoxynivalenol (DON) or partially feeding (pair-fed) can significantly reduce mortality rates when infected with Flavobacterium psychrophilum. Fasted or DON-fed fish showed increased autophagy in the liver, while fasted fish showed decreased autophagy in muscle. Treatment with chloroquine (CQ) increased Atg gene expression in the liver. The mechanisms behind the resistance of rainbow trout fed DON, CQ, or pair-fed to F. psychrophilum infection are still unclear.
JOURNAL OF FISH DISEASES
(2022)
Article
Microbiology
David Huyben, Maureen Jarau, Janet MacInnes, Roselynn Stevenson, John Lumsden
Summary: The diversity and composition of intestinal microbiota in rainbow trout were analyzed using next-generation sequencing (NGS). The study found that prophylactic oral treatment with antibiotics and infection with Flavobacterium psychrophilum altered the composition of intestinal microbiota in rainbow trout, and this alteration persisted for at least 24 days after infection.
Article
Fisheries
Brian W. Avila, Dana L. Winkelman, Eric R. Fetherman
Summary: Research has shown that rainbow trout crosses created by mating resistant strains can exhibit some level of pathogen resistance, but not all crosses show resistance, and only a few multigenerational strains are suitable for further evaluation.
JOURNAL OF FISH DISEASES
(2022)
Article
Microbiology
Valentina L. Donati, Inger Dalsgaard, Anniina Runtuvuori-Salmela, Heidi Kunttu, Johanna Jorgensen, Daniel Castillo, Lotta-Riina Sundberg, Mathias Middelboe, Lone Madsen
Summary: The study focused on potential bacteriophages against pathogenic bacteria associated with rainbow trout eyed eggs. Results showed strong potential for short term (24 h) phage control of Flavobacterium psychrophilum, but limitations in affecting F. columnare. Further studies are needed to explore long-term phage control and interaction mechanisms with fish eggs.
Article
Microbiology
Brian W. Avila, Kathryn P. Huyvaert, Dana L. Winkelman, Eric R. Fetherman
Summary: Infectious bacterial pathogens are a major concern in aquaculture, leading to significant financial losses. This study reviewed the literature on Flavobacterium psychrophilum, a common salmonid pathogen causing bacterial coldwater disease, and used Bayesian analysis to examine rainbow trout mortality patterns in laboratory challenges. The study found that injection as the exposure method resulted in higher mortality compared to bath immersion, different bacterial isolates had varying effects on mortality, and bacterial dose interacted with fish weight and exposure method.
Article
Biotechnology & Applied Microbiology
Segolene Calvez, Nora Navarro-Gonzalez, Charlene Siekoula-Nguedia, Catherine Fournel, Eric Duchaud
Summary: This study assessed the genetic diversity of Flavobacterium psychrophilum isolates from apparently healthy rainbow trout from several fish farms in the same watershed in France. High diversity was revealed by two different genotyping methods, with the majority of isolates being unrelated to the predominant clonal complex worldwide. Thirteen novel sequence types were discovered, suggesting a diverse subpopulation of F. psychrophilum in rainbow trout.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2021)
Article
Environmental Sciences
Eva Hogfors-Ronnholm, Stephan Christel, Krister Dalhem, Tom Lillhonga, Sten Engblom, Peter Osterholm, Mark Dopson
SCIENCE OF THE TOTAL ENVIRONMENT
(2018)
Article
Fisheries
Eva Hogfors-Ronnholm, Tom Wiklund
DISEASES OF AQUATIC ORGANISMS
(2010)
Article
Fisheries
E. Hogfors-Ronnholm, J. Norrgard, T. Wiklund
JOURNAL OF FISH DISEASES
(2015)
Article
Immunology
Eva Hogfors-Ronnholm, Tom Wiklund
MICROBIAL PATHOGENESIS
(2010)
Article
Immunology
Eva Hogfors-Ronnholm, Tom Wiklund
MICROBIAL PATHOGENESIS
(2012)
Article
Microbiology
Stephan Christel, Changxun Yu, Xiaofen Wu, Sarah Josefsson, Tom Lillhonga, Eva Hogfors-Ronnholm, Gustav Sohlenius, Mats E. Astrom, Mark Dopson
RESEARCH IN MICROBIOLOGY
(2019)
Article
Multidisciplinary Sciences
Eva Hogfors-Ronnholm, Margarita Lopez-Fernandez, Stephan Christel, Diego Brambilla, Marcel Huntemann, Alicia Clum, Brian Foster, Bryce Foster, Simon Roux, Krishnaveni Palaniappan, Neha Varghese, Supratim Mukherjee, T. B. K. Reddy, Chris Daum, Alex Copeland, I-Min A. Chen, Natalia N. Ivanova, Nikos C. Kyrpides, Miranda Harmon-Smith, Emiley A. Eloe-Fadrosh, Daniel Lundin, Sten Engblom, Mark Dopson
Article
Environmental Sciences
Anders Johnson, Eva Hogfors-Ronnholm, Sten Engblom, Peter Osterholm, Mats Astrom, Mark Dopson
Summary: Sediments along the Baltic Sea coast can contain high amounts of metal sulfides, which, if not handled properly, can release acid and toxic metals into water bodies. This study found that dredge spoils deposited in two river estuaries in western Finland were rapidly converted into severely acidic soil, similar to actual acid sulfate soil, despite the application of agricultural lime. It is suggested that future dredging and deposition of dredge spoils containing metal sulfides should consider the amount, grain size, and mixing of lime used.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Cell Biology
Brayon J. Fremin, Ami S. Bhatt, Nikos C. Kyrpides
Summary: This study used a large-scale comparative genomics approach to discover that small genes are more prevalent in phage genomes than in host prokaryotic genomes. These small genes may have important functions, such as encoding anti-CRISPR proteins and antimicrobial proteins.
Article
Geochemistry & Geophysics
Eva HoGFORS-rONNHOLM, Pekka Sten, Stephan Christel, Soren Frojdo, Tom Lillhonga, Pawel Nowak, Peter Osterholm, Mark Dopson, Sten Engblom
Summary: When sulfidic parent sediments are oxidized, they become acid sulfate soils that discharge metal-laden acidic solutions, posing risks to the environment, infrastructure, and human health. This study shows that a combination treatment with calcium carbonate and peat suspensions can effectively mitigate the negative effects of acid sulfate soils by improving the geochemistry, microbial community, and permeate quality of these soils.
APPLIED GEOCHEMISTRY
(2023)
Article
Environmental Sciences
Eva Hogfors-Ronnholm, Daniel Lundin, Diego Brambilla, Stephan Christel, Margarita Lopez-Fernandez, Tom Lillhonga, Sten Engblom, Peter Osterholm, Mark Dopson
Summary: This study revealed distinct microbial communities and activities in various stages of acid sulfate soils, with Gallionella and Sulfuricella dominating the community during the conversion process.
COMMUNICATIONS EARTH & ENVIRONMENT
(2022)
Article
Ecology
Eva Hogfors-Ronnholm, Stephan Christel, Tom Lillhonga, Sten Engblom, Peter Osterholm, Mark Dopson
SOIL ECOLOGY LETTERS
(2020)
Article
Multidisciplinary Sciences
Eva Hogfors-Ronnholm, Stephan Christel, Sten Engblom, Mark Dopson
Article
Environmental Sciences
Carina Bjorkblom, Eva Hogfors, Lotta Salste, Eija Bergelin, Per-Erik Olsson, Ioanna Katsiadaki, Tom Wiklund
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2009)