Th17 lymphocytes traffic to the central nervous system independently of α4 integrin expression during EAE

Cutting Edge: Th1 Cells Facilitate the Entry of Th17 Cells to the Central Nervous System during Experimental Autoimmune Encephalomyelitis

(2014) R. A. O'Connor et al.   JOURNAL OF IMMUNOLOGY

Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeability

(2011) Dörte Schulte et al.   EMBO JOURNAL

CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity

(2011) Lillian Cruz-Orengo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Fate mapping of IL-17-producing T cells in inflammatory responses

(2011) Keiji Hirota et al.   NATURE IMMUNOLOGY

Reduced Treg frequency in LFA-1-deficient mice allows enhanced T effector differentiation and pathology in EAE

(2010) Sandra Gültner et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Genetic proof for the transient nature of the Th17 phenotype

(2010) Florian C. Kurschus et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

γδ T Cells Enhance Autoimmunity by Restraining Regulatory T Cell Responses via an Interleukin-23-Dependent Mechanism

(2010) Franziska Petermann et al.   IMMUNITY

Differential Roles for Endothelial ICAM-1, ICAM-2, and VCAM-1 in Shear-Resistant T Cell Arrest, Polarization, and Directed Crawling on Blood-Brain Barrier Endothelium

(2010) O. Steiner et al.   JOURNAL OF IMMUNOLOGY

Cell Adhesion Molecules Regulate Fibrotic Process via Th1/Th2/Th17 Cell Balance in a Bleomycin-Induced Scleroderma Model

(2010) A. Yoshizaki et al.   JOURNAL OF IMMUNOLOGY

Functional and Pathogenic Differences of Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis

(2010) Helena S. Domingues et al.   PLoS One

T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-β

(2009) Luca Durelli et al.   ANNALS OF NEUROLOGY

Preferential recruitment of interferon-γ-expressing TH17 cells in multiple sclerosis

(2009) Hania Kebir et al.   ANNALS OF NEUROLOGY

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

IL-23-driven encephalo-tropism and Th17 polarization during CNS-inflammationin vivo

(2009) Gabor Gyülvészi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CCR6 regulates EAE pathogenesis by controlling regulatory CD4+T‐cell recruitment to target tissues

(2009) Ricardo Villares et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Late Developmental Plasticity in the T Helper 17 Lineage

(2009) Yun Kyung Lee et al.   IMMUNITY

Th1, Th17, and Th9 Effector Cells Induce Experimental Autoimmune Encephalomyelitis with Different Pathological Phenotypes

(2009) A. Jager et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: IL-23 Receptor GFP Reporter Mice Reveal Distinct Populations of IL-17-Producing Cells

(2009) Amit Awasthi et al.   JOURNAL OF IMMUNOLOGY

 2-Integrins in demyelinating disease: not adhering to the paradigm

(2009) X. Hu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mice deficient for CCR6 fail to control chronic experimental autoimmune encephalomyelitis

(2009) Adam Elhofy et al.   JOURNAL OF NEUROIMMUNOLOGY

Severe relapses after the first infusion of natalizumab in active relapsing—remitting multiple sclerosis

(2009) Francesca Rinaldi et al.   Multiple Sclerosis Journal

Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions

(2009) Ingo Bartholomäus et al.   NATURE

C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE

(2009) Andrea Reboldi et al.   NATURE IMMUNOLOGY

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo

(2009) Mandy J McGeachy et al.   NATURE IMMUNOLOGY

Endothelial basement membrane laminin α5 selectively inhibits T lymphocyte extravasation into the brain

(2009) Chuan Wu et al.   NATURE MEDICINE

Natalizumab treatment is associated with peripheral sequestration of proinflammatory T cells

(2009) P. Kivisakk et al.   NEUROLOGY

The blood–brain and the blood–cerebrospinal fluid barriers: function and dysfunction

(2009) Britta Engelhardt et al.   Seminars in Immunopathology

Localizing central nervous system immune surveillance: Meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis

(2008) Pia Kivisäkk et al.   ANNALS OF NEUROLOGY

Decrease in the Numbers of Dendritic Cells and CD4+ T Cells in Cerebral Perivascular Spaces Due to Natalizumab

(2008) Maria del Pilar Martin   ARCHIVES OF NEUROLOGY

IL-12– and IL-23–modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition

(2008) Mark A. Kroenke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regional CNS responses to IFN-γ determine lesion localization patterns during EAE pathogenesis

(2008) Jason R. Lees et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

(2008) Michelle A. Lowes et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Paradoxically aggressive multiple sclerosis in the face of natalizumab therapy

(2008) JR Berger   Multiple Sclerosis Journal

The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt

(2008) Nicolas Manel et al.   NATURE IMMUNOLOGY

Differential regulation of central nervous system autoimmunity by TH1 and TH17 cells

(2008) Ingunn M Stromnes et al.   NATURE MEDICINE

Immunologic, clinical, and radiologic status 14 months after cessation of natalizumab therapy

(2008) O. Stuve et al.   NEUROLOGY