MKL1 potentiates lung cancer cell migration and invasion by epigenetically activating MMP9 transcription

Myocardin related transcription factor A programs epigenetic activation of hepatic stellate cells

(2015) Wenfang Tian et al.   JOURNAL OF HEPATOLOGY

MRTF-A mediates LPS-induced pro-inflammatory transcription by interacting with the COMPASS complex

(2014) L. Yu et al.   JOURNAL OF CELL SCIENCE

SAP domain-dependent Mkl1 signaling stimulates proliferation and cell migration by induction of a distinct gene set indicative of poor prognosis in breast cancer patients

(2014) Irem Gurbuz et al.   Molecular Cancer

Neuronal Matrix Metalloproteinase-9 Is a Determinant of Selective Neurodegeneration

(2014) Artem Kaplan et al.   NEURON

MRTF-A steers an epigenetic complex to activate endothelin-induced pro-inflammatory transcription in vascular smooth muscle cells

(2014) Yuyu Yang et al.   NUCLEIC ACIDS RESEARCH

Megakaryocytic Leukemia 1 (MKL1) Regulates Hypoxia Induced Pulmonary Hypertension in Rats

(2014) Zhibin Yuan et al.   PLoS One

The cancer secretome, current status and opportunities in the lung, breast and colorectal cancer context

(2013) Tieneke B.M. Schaaij-Visser et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The role of the tumor-microenvironment in lung cancer-metastasis and its relationship to potential therapeutic targets

(2013) Steven L. Wood et al.   CANCER TREATMENT REVIEWS

Brahma-related gene 1 (Brg1) epigenetically regulates CAM activation during hypoxic pulmonary hypertension

(2013) Dewei Chen et al.   CARDIOVASCULAR RESEARCH

SET1 and p300 Act Synergistically, through Coupled Histone Modifications, in Transcriptional Activation by p53

(2013) Zhanyun Tang et al.   CELL

Myocardin related transcription factors are required for coordinated cell cycle progression

(2013) Dmitry Shaposhnikov et al.   CELL CYCLE

Proinflammatory Stimuli Engage Brahma Related Gene 1 and Brahma in Endothelial Injury

(2013) Fei Fang et al.   CIRCULATION RESEARCH

Regulation of Matrix Metalloproteinase-9 by Epigenetic Modifications and the Development of Diabetic Retinopathy

(2013) Q. Zhong et al.   DIABETES

Depletion of the transcriptional coactivators megakaryoblastic leukaemia 1 and 2 abolishes hepatocellular carcinoma xenograft growth by inducing oncogene-induced senescence

(2013) Veronika Hampl et al.   EMBO Molecular Medicine

Hepatocellular carcinoma-associated mesenchymal stem cells promote hepatocarcinoma progression: Role of the S100A4-miR155-SOCS1-MMP9 axis

(2013) Xin-Long Yan et al.   HEPATOLOGY

Epigenetic regulation of hypoxia-responsive gene expression: Focusing on chromatin and DNA modifications

(2013) Ya-Ping Tsai et al.   INTERNATIONAL JOURNAL OF CANCER

PIASy mediates hypoxia-induced SIRT1 transcriptional repression and epithelial-to-mesenchymal transition in ovarian cancer cells

(2013) L. Sun et al.   JOURNAL OF CELL SCIENCE

Endothelial SRF/MRTF ablation causes vascular disease phenotypes in murine retinae

(2013) Christine Weinl et al.   JOURNAL OF CLINICAL INVESTIGATION

Retracted: Role of STAT3 and vitamin D receptor inEZH2-mediated invasion of human colorectal cancer

(2013) Yan-Wei Lin et al.   JOURNAL OF PATHOLOGY

A SUMOylation-Dependent Pathway Regulates SIRT1 Transcription and Lung Cancer Metastasis

(2013) Lina Sun et al.   JNCI-Journal of the National Cancer Institute

Id2 Complexes with the SNAG Domain of Snai1 Inhibiting Snai1-Mediated Repression of Integrin  4

(2013) C. Chang et al.   MOLECULAR AND CELLULAR BIOLOGY

Megakaryocytic leukemia 1 (MKL1) ties the epigenetic machinery to hypoxia-induced transactivation of endothelin-1

(2013) Yuyu Yang et al.   NUCLEIC ACIDS RESEARCH

Targeting the Epigenome in Lung Cancer: Expanding Approaches to Epigenetic Therapy

(2013) Marko Jakopovic et al.   Frontiers in Oncology

The COMPASS Family of Histone H3K4 Methylases: Mechanisms of Regulation in Development and Disease Pathogenesis

(2012) Ali Shilatifard   Annual Review of Biochemistry

Lung cancer stem cells: Progress and prospects

(2012) Amber Lundin et al.   CANCER LETTERS

Myocardin-related transcription factor A regulates expression of Bok and Noxa and is involved in apoptotic signalling

(2012) Dmitry Shaposhnikov et al.   CELL CYCLE

Brahma-related gene 1 bridges epigenetic regulation of proinflammatory cytokine production to steatohepatitis in mice

(2012) Wenfang Tian et al.   HEPATOLOGY

The Trithorax Group Protein Ash2l Is Essential for Pluripotency and Maintaining Open Chromatin in Embryonic Stem Cells

(2012) Ma Wan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SMYD3 Promotes Cancer Invasion by Epigenetic Upregulation of the Metalloproteinase MMP-9

(2011) A. M. Cock-Rada et al.   CANCER RESEARCH

Myocardin-Related Transcription Factor A Mediates OxLDL-Induced Endothelial Injury

(2011) Fei Fang et al.   CIRCULATION RESEARCH

Interplay between HDAC3 and WDR5 Is Essential for Hypoxia-Induced Epithelial-Mesenchymal Transition

(2011) Min-Zu Wu et al.   MOLECULAR CELL

Histone demethylase JARID1B/KDM5B is a corepressor of TIEG1/KLF10

(2010) Joanna Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hypoxia Induces Trimethylated H3 Lysine 4 by Inhibition of JARID1A Demethylase

(2010) X. Zhou et al.   CANCER RESEARCH

MRTF-A/B suppress the oncogenic properties of v-ras- and v-src-mediated transformants

(2010) T. Yoshio et al.   CARCINOGENESIS

ING2 controls the G1to S-phase transition by regulating p21 expression

(2010) Delphine Larrieu et al.   CELL CYCLE

Activation and Repression of Cellular Immediate Early Genes by Serum Response Factor Cofactors

(2010) Seung-Min Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Linking actin dynamics and gene transcription to drive cellular motile functions

(2010) Eric N. Olson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Microenvironmental modulation of asymmetric cell division in human lung cancer cells

(2010) S. R. Pine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The SWI/SNF Chromatin Remodeling Complex Regulates Myocardin-Induced Smooth Muscle–Specific Gene Expression

(2009) Jiliang Zhou et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9

(2009) L. Gilles et al.   BLOOD

LYR71, a derivative of trimeric resveratrol, inhibits tumorigenesis by blocking STAT3-mediated matrix metalloproteinase 9 expression

(2009) Ja Eun Kim et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Mechanical Regulation of the Proangiogenic Factor CCN1/CYR61 Gene Requires the Combined Activities of MRTF-A and CREB-binding Protein Histone Acetyltransferase

(2009) Mary Hanna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of  4-integrin expression by epigenetic modifications in the mammary gland and during the epithelial-to-mesenchymal transition

(2009) X. Yang et al.   JOURNAL OF CELL SCIENCE

Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis

(2009) Souhila Medjkane et al.   NATURE CELL BIOLOGY

Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-κB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes

(2009) I Robert et al.   ONCOGENE

Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation

(2008) Ali Shilatifard   CURRENT OPINION IN CELL BIOLOGY

TGF-β and tumors—an ill-fated alliance

(2008) Niki M Moutsopoulos et al.   CURRENT OPINION IN IMMUNOLOGY

Lung cancer epigenetics and genetics

(2008) Angela Risch et al.   INTERNATIONAL JOURNAL OF CANCER

HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells

(2008) Xiaocen Kong et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY