LRIG1 opposes epithelial-to-mesenchymal transition and inhibits invasion of basal-like breast cancer cells
出版年份 2015 全文链接
标题
LRIG1 opposes epithelial-to-mesenchymal transition and inhibits invasion of basal-like breast cancer cells
作者
关键词
-
出版物
ONCOGENE
Volume 35, Issue 22, Pages 2932-2947
出版商
Springer Nature
发表日期
2015-09-21
DOI
10.1038/onc.2015.345
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer
- (2015) Christine Mehner et al. Oncotarget
- Suppression of triple-negative breast cancer metastasis by pan-DAC inhibitor panobinostat via inhibition of ZEB family of EMT master regulators
- (2014) Lyndsay V. Rhodes et al. BREAST CANCER RESEARCH AND TREATMENT
- Expression of LRIG1 is associated with good prognosis and human papillomavirus status in oropharyngeal cancer
- (2014) D Lindquist et al. BRITISH JOURNAL OF CANCER
- Loss of LRIG1 Locus Increases Risk of Early and Late Relapse of Stage I/II Breast Cancer
- (2014) P. A. Thompson et al. CANCER RESEARCH
- Architecture of tight junctions and principles of molecular composition
- (2014) Christina M. Van Itallie et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Membrane-Initiated Estradiol Signaling of Epithelial-Mesenchymal Transition-Associated Mechanisms Through Regulation of Tight Junctions in Human Breast Cancer Cells
- (2014) Javier E. Jiménez-Salazar et al. Hormones & Cancer
- Basal-Like Breast Cancer: Update on Clinicopathologic, Immunohistochemical, and Molecular Features
- (2013) Jennifer Leidy et al. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
- LRIG1 is a triple threat: ERBB negative regulator, intestinal stem cell marker and tumour suppressor
- (2013) Y Wang et al. BRITISH JOURNAL OF CANCER
- C-Met in invasive breast cancer
- (2013) Colan M. Ho-Yen et al. CANCER
- CUL4A Induces Epithelial–Mesenchymal Transition and Promotes Cancer Metastasis by Regulating ZEB1 Expression
- (2013) Yunshan Wang et al. CANCER RESEARCH
- Platycodin D inhibits migration, invasion, and growth of MDA-MB-231 human breast cancer cells via suppression of EGFR-mediated Akt and MAPK pathways
- (2013) Jaemoo Chun et al. CHEMICO-BIOLOGICAL INTERACTIONS
- MET is a potential target for use in combination therapy with EGFR inhibition in triple-negative/basal-like breast cancer
- (2013) Yu Jin Kim et al. INTERNATIONAL JOURNAL OF CANCER
- Leucine-rich Repeat and Immunoglobulin Domain-containing Protein-1 (Lrig1) Negative Regulatory Action toward ErbB Receptor Tyrosine Kinases Is Opposed by Leucine-rich Repeat and Immunoglobulin Domain-containing Protein 3 (Lrig3)
- (2013) Hanine Rafidi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- LRIG1 inhibits STAT3-dependent inflammation to maintain corneal homeostasis
- (2013) Takahiro Nakamura et al. JOURNAL OF CLINICAL INVESTIGATION
- Restoration of LRIG1 suppresses bladder cancer cell growth by directly targeting EGFR activity
- (2013) Lei Chang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- LRIG1 modulates aggressiveness of head and neck cancers by regulating EGFR-MAPK-SPHK1 signaling and extracellular matrix remodeling
- (2013) J J-C Sheu et al. ONCOGENE
- Lrig2-Deficient Mice Are Protected against PDGFB-Induced Glioma
- (2013) Veronica Rondahl et al. PLoS One
- Molecular insights on basal-like breast cancer
- (2012) Mev Dominguez Valentin et al. BREAST CANCER RESEARCH AND TREATMENT
- Mesenchymal–epithelial transition (MET) as a mechanism for metastatic colonisation in breast cancer
- (2012) N. P. A. Devika Gunasinghe et al. CANCER AND METASTASIS REVIEWS
- LRIG1 Modulates Cancer Cell Sensitivity to Smac Mimetics by Regulating TNF Expression and Receptor Tyrosine Kinase Signaling
- (2012) L. Bai et al. CANCER RESEARCH
- Suppression of the Epithelial-Mesenchymal Transition by Grainyhead-like-2
- (2012) B. Cieply et al. CANCER RESEARCH
- The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor
- (2012) Anne E. Powell et al. CELL
- LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development
- (2012) Liwen Lu et al. JOURNAL OF PATHOLOGY
- c-Myb regulates matrix metalloproteinases 1/9, and cathepsin D: implications for matrix-dependent breast cancer cell invasion and metastasis
- (2012) Lucia Knopfová et al. Molecular Cancer
- Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling
- (2012) Vivian W. Y. Wong et al. NATURE CELL BIOLOGY
- Cbl-independent degradation of Met: ways to avoid agonism of bivalent Met-targeting antibody
- (2012) J M Lee et al. ONCOGENE
- Overexpression of c-Met promotes invasion and metastasis of small oral tongue carcinoma
- (2012) Young Chang Lim et al. ORAL ONCOLOGY
- The T Box Transcription Factor TBX2 Promotes Epithelial-Mesenchymal Transition and Invasion of Normal and Malignant Breast Epithelial Cells
- (2012) Bin Wang et al. PLoS One
- Met Receptor Acts Uniquely for Survival and Morphogenesis of EGFR-Dependent Normal Mammary Epithelial and Cancer Cells
- (2012) Paolo Accornero et al. PLoS One
- Cardiotoxin III suppresses MDA-MB-231 cell metastasis through the inhibition of EGF/EGFR-mediated signaling pathway
- (2012) Pei-Chien Tsai et al. TOXICON
- A Gene Signature for Predicting Outcome in Patients with Basal-like Breast Cancer
- (2012) Robin M. Hallett et al. Scientific Reports
- bc-GenExMiner: an easy-to-use online platform for gene prognostic analyses in breast cancer
- (2011) Pascal Jézéquel et al. BREAST CANCER RESEARCH AND TREATMENT
- Lrig1 Is an Estrogen-Regulated Growth Suppressor and Correlates with Longer Relapse-Free Survival in ER -Positive Breast Cancer
- (2011) S. R. Krig et al. MOLECULAR CANCER RESEARCH
- Synergistic Effects of Foretinib with HER-Targeted Agents in MET and HER1- or HER2-Coactivated Tumor Cells
- (2011) L. Liu et al. MOLECULAR CANCER THERAPEUTICS
- An EMT–Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype
- (2011) Irina M. Shapiro et al. PLoS Genetics
- Identifying common prognostic factors in genomic cancer studies: A novel index for censored outcomes
- (2010) Sigrid Rouam et al. BMC BIOINFORMATICS
- Tyrosine Phosphorylation Profiling Reveals the Signaling Network Characteristics of Basal Breast Cancer Cells
- (2010) F. Hochgrafe et al. CANCER RESEARCH
- The Met receptor tyrosine kinase and basal breast cancer
- (2010) Marisa G. Ponzo et al. CELL CYCLE
- Epithelial-Mesenchymal Transition (EMT) in Tumor-Initiating Cells and Its Clinical Implications in Breast Cancer
- (2010) Chad J. Creighton et al. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
- Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition
- (2010) Yvonne L Chao et al. Molecular Cancer
- ARQ 197, a Novel and Selective Inhibitor of the Human c-Met Receptor Tyrosine Kinase with Antitumor Activity
- (2010) N. Munshi et al. MOLECULAR CANCER THERAPEUTICS
- Mesenchymal/Stromal Gene Expression Signature Relates to Basal-Like Breast Cancers, Identifies Bone Metastasis and Predicts Resistance to Therapies
- (2010) Cristina Marchini et al. PLoS One
- Expression of aldehyde dehydrogenase 1 (ALDH1) is associated with basal-like markers and features of aggressive tumours in African breast cancer
- (2009) H Nalwoga et al. BRITISH JOURNAL OF CANCER
- Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
- (2009) B. T. Hennessy et al. CANCER RESEARCH
- Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis
- (2009) Kim B. Jensen et al. Cell Stem Cell
- Epidermal stem cell diversity and quiescence
- (2009) Fiona M. Watt et al. EMBO Molecular Medicine
- Met induces mammary tumors with diverse histologies and is associated with poor outcome and human basal breast cancer
- (2009) M. G. Ponzo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epithelial-Mesenchymal Transition in Breast Cancer Relates to the Basal-like Phenotype
- (2008) D. Sarrio et al. CANCER RESEARCH
- Suppression of the Negative Regulator LRIG1 Contributes to ErbB2 Overexpression in Breast Cancer
- (2008) J. K. Miller et al. CANCER RESEARCH
- Direct Evidence for Epithelial-Mesenchymal Transitions in Breast Cancer
- (2008) A. J. Trimboli et al. CANCER RESEARCH
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- Lrig1 Is an Endogenous Inhibitor of Ret Receptor Tyrosine Kinase Activation, Downstream Signaling, and Biological Responses to GDNF
- (2008) F. Ledda et al. JOURNAL OF NEUROSCIENCE
- LRIG1 negatively regulates the oncogenic EGF receptor mutant EGFRvIII
- (2008) M A Stutz et al. ONCOGENE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search