Dysregulated protease activated receptor 1 (PAR1) promotes metastatic phenotype in breast cancer through HMGA2

IMP-3 Promotes Migration and Invasion of Melanoma Cells by Modulating the Expression of HMGA2 and Predicts Poor Prognosis in Melanoma

(2015) Yi-Shuan Sheen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

HMGA1 promotes metastatic processes in basal-like breast cancer regulating EMT and stemness

(2015) Silvia Pegoraro et al.   Oncotarget

HMGA2 induces transcription factor Slug expression to promote epithelial-to-mesenchymal transition and contributes to colon cancer progression

(2014) Yang Li et al.   CANCER LETTERS

Effects of HMGA2 on malignant degree, invasion, metastasis, proliferation and cellular morphology of ovarian cancer cells

(2014) Yan-Ni Xi et al.   Asian Pacific Journal of Tropical Medicine

HMGA2 functions as a competing endogenous RNA to promote lung cancer progression

(2013) Madhu S. Kumar et al.   NATURE

Suppression of Arterial Thrombosis Without Affecting Hemostatic Parameters With a Cell-Penetrating PAR1 Pepducin

(2012) Ping Zhang et al.   CIRCULATION

Regulation of human protease-activated receptor 1 (hPar1) gene expression in breast cancer by estrogen

(2012) Zaidoun Salah et al.   FASEB JOURNAL

Vorapaxar in the Secondary Prevention of Atherothrombotic Events

(2012) David A. Morrow et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting Protease-Activated Receptor-1 with Cell-Penetrating Pepducins in Lung Cancer

(2011) Jaroslaw Cisowski et al.   AMERICAN JOURNAL OF PATHOLOGY

Vimentin in cancer and its potential as a molecular target for cancer therapy

(2011) Arun Satelli et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Thrombin-Receptor Antagonist Vorapaxar in Acute Coronary Syndromes

(2011) Pierluigi Tricoci et al.   NEW ENGLAND JOURNAL OF MEDICINE

High-Mobility Group A (HMGA) Proteins and Breast Cancer

(2010) Silvia Peluso et al.   Breast Care

Vimentin Is a Novel Anti-Cancer Therapeutic Target; Insights from In Vitro and In Vivo Mice Xenograft Studies

(2010) Guy Lahat et al.   PLoS One

Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling

(2010) C. M. Fillmore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HMGA molecular network: From transcriptional regulation to chromatin remodeling

(2009) Riccardo Sgarra et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Nuclear functions of the HMG proteins

(2009) Raymond Reeves   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Blockade of PAR1 Signaling with Cell-Penetrating Pepducins Inhibits Akt Survival Pathways in Breast Cancer Cells and Suppresses Tumor Survival and Metastasis

(2009) E. Yang et al.   CANCER RESEARCH

Safety and tolerability of SCH 530348 in patients undergoing non-urgent percutaneous coronary intervention: a randomised, double-blind, placebo-controlled phase II study

(2009) Richard C Becker et al.   LANCET

Proteinase-Activated Receptor-1-Triggered Activation of Tumor Progression Locus-2 Promotes Actin Cytoskeleton Reorganization and Cell Migration

(2008) M. Hatziapostolou et al.   CANCER RESEARCH

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

HMGA2 and Smads Co-regulate SNAIL1 Expression during Induction of Epithelial-to-Mesenchymal Transition

(2008) Sylvie Thuault et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer

(2008) A. Agarwal et al.   MOLECULAR CANCER THERAPEUTICS